HSP70s: From Tumor Transformation to Cancer Therapy. (Q35181079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892295%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

HSP70s: From Tumor Transformation to Cancer Therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892295%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Chih-Wen Shu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892295%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Chun-Ming Huang

series ordinal

2

1 reference

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12 February 2020

publication date

24 April 2008

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Clinical medicine. Oncology

12 February 2020

published in

1 reference

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12 February 2020

volume

2

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12 February 2020

page(s)

335-345

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GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis

12 February 2020

cites work

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All in the family: atypical Hsp70 chaperones are conserved modulators of Hsp70 activity.

13 July 2018

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Labeling and identification of LNCaP cell surface proteins: a pilot study

13 July 2018

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GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis

13 July 2018

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p53 alterations in human cancer: more questions than answers.

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Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery

13 July 2018

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Mortalin sensitizes human cancer cells to MKT-077-induced senescence

13 July 2018

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Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer

13 July 2018

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Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum

13 July 2018

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Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer

13 July 2018

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The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis

13 July 2018

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(-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78.

13 July 2018

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BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis

13 July 2018

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GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer

13 July 2018

1 reference

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Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest

13 July 2018

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A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells

13 July 2018

1 reference

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Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers

13 July 2018

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Endoplasmic reticulum stress in health and disease

13 July 2018

1 reference

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Proteomic analysis of autoantibodies in patients with hepatocellular carcinoma

13 July 2018

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Control of metastasized pancreatic carcinomas in SCID/beige mice with human IL-2/TKD-activated NK cells.

13 July 2018

1 reference

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Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

13 July 2018

1 reference

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Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.

13 July 2018

1 reference

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Immunostimulatory functions of membrane-bound and exported heat shock protein 70.

13 July 2018

1 reference

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Enhanced sensitivity to mitomycin C by abating heat shock protein 70 expression in human bladder cancer cell line of BIU-87.

13 July 2018

1 reference

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Sick chaperones, cellular stress, and disease

13 July 2018

1 reference

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Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells

13 July 2018

1 reference

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Endoplasmic reticulum stress signal mediators are targets of selenium action

13 July 2018

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Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways

13 July 2018

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Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides.

13 July 2018

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Co-expression of heat shock protein 70 and glucose-regulated protein 94 in human gastric carcinoma cell line BGC-823

13 July 2018

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Hsp70 chaperones: cellular functions and molecular mechanism

13 July 2018

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Correlation between clinicopathology and expression of heat shock protein 70 and glucose-regulated protein 94 in human colonic adenocarcinoma

13 July 2018

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Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

13 July 2018

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Transactivation of hsp70-1/2 in geldanamycin-treated human non-small cell lung cancer H460 cells: involvement of intracellular calcium and protein kinase C.

13 July 2018

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Expression and significance of heat shock protein 70 and glucose-regulated protein 94 in human esophageal carcinoma

13 July 2018

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Heat shock protein 70 antisense oligonucleotide inhibits cell growth and induces apoptosis in human gastric cancer cell line SGC-7901.

13 July 2018

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Exosomes: a new delivery system for tumor antigens in cancer immunotherapy.

13 July 2018

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Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.

13 July 2018

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hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

13 July 2018

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Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.

13 July 2018

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HSP27 and HSP70: potentially oncogenic apoptosis inhibitors

13 July 2018

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Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients

13 July 2018

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Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

13 July 2018

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Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes

13 July 2018

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Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

13 July 2018

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Interaction of heat shock protein 70 peptide with NK cells involves the NK receptor CD94.

13 July 2018

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

13 July 2018

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Analysis of heat-shock related gene expression in head-and-neck cancer using cDNA arrays

13 July 2018

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Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis

13 July 2018

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Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

13 July 2018

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Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

13 July 2018

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A 14-mer Hsp70 peptide stimulates natural killer (NK) cell activity

13 July 2018

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Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth.

13 July 2018

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Cell-cycle dependent tyrosine phosphorylation on mortalin regulates its interaction with fibroblast growth factor-1.

13 July 2018

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The chaperone function of hsp70 is required for protection against stress-induced apoptosis

13 July 2018

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Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

13 July 2018

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Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells

13 July 2018

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A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma

13 July 2018

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ATPase activity of the heat shock protein hsp72 is dispensable for its effects on dephosphorylation of stress kinase JNK and on heat-induced apoptosis

13 July 2018

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Heterogeneous patterns of constitutive and heat shock induced expression of HLA-linked HSP70-1 and HSP70-2 heat shock genes in human melanoma cell lines

13 July 2018

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Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: a possible role in induced radioresistance

13 July 2018

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The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila

13 July 2018

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

13 July 2018

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Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria

13 July 2018

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Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2)

13 July 2018

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Structure and expression of a human gene coding for a 71 kd heat shock 'cognate' protein

13 July 2018

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Localization of a human heat-shock HSP 70 gene sequence to chromosome 6 and detection of two other loci by somatic-cell hybrid and restriction fragment length polymorphism analysis

13 July 2018

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Structure and expression of the three MHC-linked HSP70 genes

13 July 2018

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The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1

13 July 2018

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Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids

13 July 2018

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Heat shock of Drosophila melanogaster induces the synthesis of new messenger RNAs and proteins

13 July 2018

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Association of HSP70-hom genetic variant with prostate cancer risk.

13 July 2018

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Microbiology: death of a chaperone.

27 September 2018

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Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity.

27 September 2018

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Mortalin controls centrosome duplication via modulating centrosomal localization of p53.

27 September 2018

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Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death

27 September 2018

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Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance.

27 September 2018

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Overexpression of glucose-regulated protein 78 in colon cancer.

27 September 2018

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Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment

27 September 2018

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The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress

27 September 2018

1 reference

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Specific interaction between Smad1 and CHIP: a surface plasmon resonance study

27 September 2018

1 reference

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Plasma levels of heat shock protein 70 in patients with prostate cancer: a potential biomarker for prostate cancer

27 September 2018

1 reference

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Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells: a clinical phase i trial.

27 September 2018

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A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling

27 September 2018

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Molecular chaperone GRP75 reprove cells from injury caused by glucose deprivation

27 September 2018

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Stress-induced release of HSC70 from human tumors

27 September 2018

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Polymorphism of the stress protein HSP70-2 gene is associated with the susceptibility to the nasopharyngeal carcinoma

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161691

Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161691

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161691

Elevated levels of mortalin expression in human brain tumors.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161691

Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy

27 September 2018

1 reference

12 December 2020

Cloning, expression, purification and preliminary X-ray crystallographic studies of Escherichia coli Hsp100 ClpB nucleotide-binding domain 1 (NBD1)

1 reference

12 December 2020

Antibodies to HSP70 and HSP90 in serum in non-small cell lung cancer patients

1 reference

12 December 2020

Cloning, expression, purification and preliminary X-ray crystallographic studies of Escherichia coli Hsp100 ClpB N-terminal domain

1 reference

12 December 2020

Proteomic analysis of vascular smooth muscle cells treated with ouabain

1 reference

12 December 2020

[Separation and identification of the exosomes derived from a mouse hepatoma carcinoma cell line (H22) and initial investigation of their protein composition]

1 reference

12 December 2020

Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance

1 reference

12 December 2020

Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

1 reference

12 December 2020

Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma

1 reference

12 December 2020

Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

1 reference

12 December 2020

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

1 reference

12 December 2020

Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

1 reference

12 December 2020

Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent Phenoxodiol-induced apoptosis of human melanoma cells

1 reference

12 December 2020

Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival

1 reference

12 December 2020

Expression of heat shock protein 70 (HSP70) in patients with colorectal adenocarcinoma--immunohistochemistry and Western blot analysis

1 reference

12 December 2020

Identifiers

DOI

10.4137/CMO.S475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892295%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892295%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference