Collagenase: a key enzyme in collagen turnover (Q41481774)

1 October 2017

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title

Collagenase: a key enzyme in collagen turnover (English)

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1 October 2017

Shingleton WD

1

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1 October 2017

Hodges DJ

series ordinal

2

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1 October 2017

Brick P

series ordinal

3

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1 October 2017

Cawston TE

series ordinal

4

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1 October 2017

1 January 1996

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Biochemistry and Cell Biology

1 October 2017

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1 October 2017

74

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1 October 2017

6

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1 October 2017

759-775

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Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

1 October 2017

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Transforming growth factor-beta causes partial inhibition of interleukin 1-stimulated cartilage degradation in vitro

21 January 2018

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The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

21 January 2018

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Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review

21 January 2018

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Proteolytic remodeling of extracellular matrix

21 January 2018

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Matrix metalloproteinases: a review

21 January 2018

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Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

21 January 2018

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Retinoids and rheumatoid arthritis: modulation of extracellular matrix by controlling expression of collagenase

21 January 2018

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Regulation of collagenase gene expression in synovial fibroblasts

21 January 2018

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Transin/stromelysin expression in the synovium of rats with experimental erosive arthritis. In situ localization and kinetics of expression of the transformation-associated metalloproteinase in euthymic and athymic Lewis rats

21 January 2018

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Purification of rabbit bone inhibitor of collagenase

21 January 2018

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The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor

21 January 2018

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Synovial fluids from infected joints contain active metalloproteinases and no inhibitory activity

21 January 2018

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Fragments of human fibroblast collagenase. Purification and characterization

21 January 2018

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Metalloproteinase domain structure, cellular invasion and metastasis

21 January 2018

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Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

21 January 2018

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Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage

21 January 2018

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Protease inhibitors: role and potential therapeutic use in human cancer

21 January 2018

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Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions

21 January 2018

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The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases

21 January 2018

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Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan

21 January 2018

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X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design

21 January 2018

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Collagenase in wound healing: effect of wound age and type

21 January 2018

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Specific degradation of the collagen molecule by tadpole collagenolytic enzyme

21 January 2018

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Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation

21 January 2018

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Tissue cooperation in a proteolytic cascade activating human interstitial collagenase

21 January 2018

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cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment

21 January 2018

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Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity

21 January 2018

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Co-culture of human breast adenocarcinoma MCF-7 cells and human dermal fibroblasts enhances the production of matrix metalloproteinases 1, 2 and 3 in fibroblasts

21 January 2018

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Structural biochemistry and activation of matrix metalloproteases

21 January 2018

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Biochemistry of articular cartilage in health and disease

21 January 2018

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Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4

21 January 2018

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Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller

21 January 2018

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The role of cellular proteases and their inhibitors in invasion and metastasis. Introductionary overview

21 January 2018

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Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself

21 January 2018

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Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase

21 January 2018

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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

21 January 2018

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The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules

21 January 2018

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Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

21 January 2018

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The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

21 January 2018

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The role of plasminogen activators in the regulation of connective tissue metalloproteinases

21 January 2018

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Identification of matrix metalloproteinases 3 (stromelysin-1) and 9 (gelatinase B) in abdominal aortic aneurysm

21 January 2018

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Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.

21 January 2018

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Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas

21 January 2018

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Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13

21 January 2018

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Furin-dependent intracellular activation of the human stromelysin-3 zymogen

21 January 2018

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Fibroblast growth factor enhances the interleukin-1-mediated chondrocytic protease release

21 January 2018

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The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

21 January 2018

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Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones

21 January 2018

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Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma

21 January 2018

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Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds

21 January 2018

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Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein.

21 January 2018

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A matrix metalloproteinase expressed on the surface of invasive tumour cells

21 January 2018

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Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma

21 January 2018

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Activation of the 92-kDa gelatinase by stromelysin and 4-aminophenylmercuric acetate. Differential processing and stabilization of the carboxyl-terminal domain by tissue inhibitor of metalloproteinases (TIMP).

21 January 2018

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Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family

21 January 2018

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Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation

21 January 2018

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1.56 A structure of mature truncated human fibroblast collagenase

21 January 2018

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Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

21 January 2018

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Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family

21 January 2018

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THE CHONDROCYTE: A CELL UNDER PRESSURE

21 January 2018

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The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

21 January 2018

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Regulation of interstitial collagenase expression and collagen degradation by retinoic acid in bone cells

21 January 2018

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Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP)

21 January 2018

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Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family

21 January 2018

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An internal cysteine plays a role in the maintenance of the latency of human fibroblast collagenase.

21 January 2018

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Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression

21 January 2018

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Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts

21 January 2018

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The secretion of the tissue inhibitor of metalloproteinases (TIMP) by human synovial fibroblasts is modulated by all-trans-retinoic acid

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O96-083

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1 October 2017

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