Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase (Q35154868)

6 August 2017

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title

Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase (English)

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6 August 2017

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Ming-Hai Wang

1

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6 August 2017

Da Wang

series ordinal

2

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6 August 2017

Yi-Qing Chen

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

22 May 2003

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6 August 2017

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6 August 2017

24

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6 August 2017

8

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6 August 2017

1291-1300

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6 August 2017

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Cancer epigenetics takes center stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Progression elevated gene-3, PEG-3, induces genomic instability in rodent and human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Receptor protein-tyrosine kinases and their signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

RTK mutations and human syndromeswhen good receptors turn bad.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The Trk family of neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Identification of the ron gene product as the receptor for the human macrophage stimulating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Chicken macrophage stimulating protein is a ligand of the receptor protein-tyrosine kinase Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Cloning and expression of Xenopus HGF-like protein (HLP) and Ron/HLP receptor implicate their involvement in early neural development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Three receptor genes for plasminogen related growth factors in the genome of the puffer fish Fugu rubripes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The putative transforming protein of S13 avian erythroblastosis virus is a transmembrane glycoprotein with an associated protein kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Characterization of the mouse Ron/Stk receptor tyrosine kinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Characterization of two monoclonal antibodies against the RON tyrosine kinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Overexpression of the RON gene in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage stimulating protein (MSP) binds to its receptor via the MSP beta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Interaction of macrophage-stimulating protein with its receptor. Residues critical for beta chain binding and evidence for independent alpha chain binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage-stimulating protein induces proliferation and migration of murine keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Overexpression and activation of the RON receptor tyrosine kinase in a panel of human colorectal carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Constitutive activation of the RON gene promotes invasive growth but not transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

MET(PRC) mutations in the Ron receptor result in upregulation of tyrosine kinase activity and acquisition of oncogenic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Targeted expression of the receptor tyrosine kinase RON in distal lung epithelial cells results in multiple tumor formation: oncogenic potential of RON in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Induction and regulation of epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Epithelial cell plasticity in development and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Functional characterization of domains contained in hepatocyte growth factor-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Role of cell-matrix contacts in cell migration and epithelial-mesenchymal transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Cross-talk between the proto-oncogenes Met and Ron

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

TGF-beta signaling by Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

The Ron oncogenic activity induced by the MEN2B-like substitution overcomes the requirement for the multifunctional docking site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Requirement of both tyrosine residues 1330 and 1337 in the C-terminal tail of the RON receptor tyrosine kinase for epithelial cell scattering and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Anti-apoptotic action of macrophage stimulating protein (MSP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Antisense anticancer oligonucleotide therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Bronchioloalveolar carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG089

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGG089

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release_nci4kazetvedndve2xeafygoty

6 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/nci4kazetvedndve2xeafygoty

mapped directly with Wikidata item

24 November 2022

based on heuristic

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