Apc and p53 interaction in DNA damage and genomic instability in hepatocytes (Q35154305)

6 August 2017

Apc and p53 interaction in DNA damage and genomic instability in hepatocytes (English)

1 reference

6 August 2017

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Owen J Sansom

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Alan R. Clarke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

V Méniel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

M Megges

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

A Cole

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

27 October 2014

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

4118-4129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.342

7 June 2020

exact match

0 references

cites work

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Centrosomes, chromosome instability (CIN) and aneuploidy

13 July 2018

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A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver

13 July 2018

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

13 July 2018

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Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma

13 July 2018

1 reference

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Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle.

13 July 2018

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Transcription dynamics in a physiological process: β-catenin signaling directs liver metabolic zonation

13 July 2018

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B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

13 July 2018

1 reference

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A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine

13 July 2018

1 reference

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Original CIN: reviewing roles for APC in chromosome instability

13 July 2018

1 reference

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APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

13 July 2018

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

13 July 2018

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

13 July 2018

1 reference

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Wnt/beta-catenin signaling in development and disease

13 July 2018

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Does aneuploidy cause cancer?

13 July 2018

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CIN By WNT: growth pathways, mitotic control and chromosomal instability in cancer

13 July 2018

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Genetics of hepatocellular tumors.

13 July 2018

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On the road to cancer: aneuploidy and the mitotic checkpoint

13 July 2018

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Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein

13 July 2018

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The switch from survival responses to apoptosis after chromosomal breaks

13 July 2018

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Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

13 July 2018

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Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

13 July 2018

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Cell death by mitotic catastrophe: a molecular definition

13 July 2018

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The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.

13 July 2018

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Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

13 July 2018

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Adenovirus-mediated Cre deletion of floxed sequences in primary mouse cells is an efficient alternative for studies of gene deletion.

13 July 2018

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Histone H3 phosphorylation and cell division

13 July 2018

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A role for the Adenomatous Polyposis Coli protein in chromosome segregation

13 July 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

13 July 2018

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A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts

13 July 2018

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Conditional disruption of Axin1 leads to development of liver tumors in mice.

13 July 2018

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Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.

27 September 2018

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27 September 2018

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

27 September 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

27 September 2018

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Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy.

27 September 2018

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MBD2 deficiency does not accelerate p53 mediated lymphomagenesis

27 September 2018

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A p53-dependent mouse spindle checkpoint

21 January 2018

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Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure

21 January 2018

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Apc deficiency predisposes to renal carcinoma in the mouse

16 November 2018

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Molecular genetics of colorectal cancer

16 November 2018

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Mutations in the APC tumour suppressor gene cause chromosomal instability

31 March 2020

1 reference

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Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25347740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.342

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347740%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference