Oligomerization of MDC1 protein is important for proper DNA damage response (Q35150138)

6 August 2017

Oligomerization of MDC1 protein is important for proper DNA damage response (English)

1 reference

6 August 2017

0 references

Kuntian Luo

1

1 reference

6 August 2017

Jian Yuan

series ordinal

2

1 reference

6 August 2017

Zhenkun Lou

series ordinal

3

1 reference

6 August 2017

language of work or name

English

0 references

publication date

24 June 2011

1 reference

Journal of Biological Chemistry

6 August 2017

1 reference

6 August 2017

286

1 reference

6 August 2017

32

1 reference

6 August 2017

28192-28199

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3151064/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Topoisomerase IIalpha controls the decatenation checkpoint

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

The DNA damage response: ten years after

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

NFBD1/MDC1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 interacts with Rad51 and facilitates homologous recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

ATRIP oligomerization is required for ATR-dependent checkpoint signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 regulates DNA-PK autophosphorylation in response to DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 is a mediator of the mammalian DNA damage checkpoint

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

MDC1 is required for the intra-S-phase DNA damage checkpoint

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Role for ATM in DNA damage-induced phosphorylation of BRCA1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

ATM-dependent phosphorylation of nibrin in response to radiation exposure

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

Megabase chromatin domains involved in DNA double-strand breaks in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151064

The cellular response to DNA damage: a focus on MDC1 and its interacting proteins

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

NFBD1/MDC1 stabilizes oncogenic MDM2 to contribute to cell fate determination in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258087

The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9-Rad9 interaction after DNA damage

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21705321

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.258087

1 reference

6 August 2017

1 reference

6 August 2017

1 reference