Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: chondrosarcoma and other cartilaginous neoplasms (Q35125621)

6 August 2017

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title

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: chondrosarcoma and other cartilaginous neoplasms (English)

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6 August 2017

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Avery A Sandberg

1

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PubMed ID

12742153

6 August 2017

Julia A Bridge

series ordinal

2

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6 August 2017

1 May 2003

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Cancer Genetics and Cytogenetics

6 August 2017

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6 August 2017

143

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6 August 2017

1

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6 August 2017

1-31

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Clonal karyotypic abnormalities of the hereditary multiple exostoses chromosomal loci 8q24.1 (EXT1) and 11p11-12 (EXT2) in patients with sporadic and hereditary osteochondromas

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Loss of chromosome band 8q24 in sporadic osteocartilaginous exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Recurrent anomalies of 6q25 in chondromyxoid fibroma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Evidence of an association between 6q13-21 chromosome aberrations and locally aggressive behavior in patients with cartilage tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

An extension of the admixture test for the study of genetic heterogeneity in hereditary multiple exostoses.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondrosarcoma in a family with multiple hereditary exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The natural history of hereditary multiple exostoses

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Natural history study of hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Intermediate grade osteosarcoma and chondrosarcoma arising in an osteochondroma. A case report of a patient with hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Malignant transformation of a multiple cartilaginous exostosis--a case report

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Hereditary multiple exostoses: confirmation of linkage to chromosomes 8 and 11.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Positional cloning of a gene involved in hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Mutations in the EXT1 and EXT2 genes in hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A gene for hereditary multiple exostoses maps to chromosome 19p.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Refined physical mapping and genomic structure of the EXTL1 gene

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Molecular dissection of a contiguous gene syndrome: localization of the genes involved in the Langer-Giedion syndrome

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Molecular analysis of overlapping chromosomal deletions in patients with Langer-Giedion syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Haploinsufficiency of ALX4 as a potential cause of parietal foramina in the 11p11.2 contiguous gene-deletion syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Germline mutations in the EXT1 and EXT2 genes in Korean patients with hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

EXT 1 gene mutation induces chondrocyte cytoskeletal abnormalities and defective collagen expression in the exostoses

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clinical correlation to genetic variations of hereditary multiple exostosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Mutation screening of the EXT1 and EXT2 genes in patients with hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytoskeletal abnormalities in chondrocytes with EXT1 and EXT2 mutations

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Diminished levels of the putative tumor suppressor proteins EXT1 and EXT2 in exostosis chondrocytes

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for Hereditary Multiple Exostoses.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

New perspectives on the molecular basis of hereditary bone tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Toward a molecular understanding of skeletal development

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Functions of fibroblast growth factors in vertebrate development

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Biologic and clinical significance of cytogenetic and molecular cytogenetic abnormalities in benign and malignant cartilaginous lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic and molecular cytogenetic evidence of recurrent 8q24.1 loss in osteochondroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Recurring breakpoints of 1p13 approximately p22 in osteochondroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Interstitial deletion of 11(p11.2p12): a newly described contiguous gene deletion syndrome involving the gene for hereditary multiple exostoses (EXT2).

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

No DNA copy number changes in osteochondromas: a comparative genomic hybridization study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Partial deletions of the CDKN2 and MTS2 putative tumor suppressor genes in a myxoid chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Frequent loss of heterozygosity for markers on chromosome arm 10q in chondrosarcomas

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Loss of heterozygosity and DNA ploidy point to a diverging genetic mechanism in the origin of peripheral and central chondrosarcoma

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Near-haploidy and subsequent polyploidization characterize the progression of peripheral chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondromyxoid fibroma of bone: a clinicopathologic review of 278 cases.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cell biology and matrix biochemistry of chondromyxoid fibroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondrosarcoma of the proximal femur with myxoid degeneration mistaken for chondromyxoid fibroma in a young adult. A case report.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic analysis of a scapular chondromyxoid fibroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Rearrangement of band q13 on both chromosomes 12 in a periosteal chondroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic findings in benign cartilaginous neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Malignant progression in multiple enchondromatosis (Ollier's disease): an autopsy-based molecular genetic study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Deletion 1p in a low-grade chondrosarcoma in a patient with Ollier disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Giant solitary synovial chondromatosis

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cell proliferation studies in primary synovial chondromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

An immunohistological study of cartilage and synovium in primary synovial chondromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Synovial chondromatosis: the possible role of FGF 9 and FGF receptor 3 in its pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondroblastoma: a clinical and radiological study of 104 cases.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Benign chondroblastoma.A study of 125 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Spindle cell non-argyrophil carcinoma of the breast with neuroendocrine differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Malignant chondroblastoma presenting as a recurrent pelvic tumor with DNA aneuploidy and p53 mutation as supportive evidence of malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

DNA and RNA content analysis by flow cytometry in the pathobiologic assessment of bone tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Human benign chondroblastoma with a pseudodiploid stemline characterized by a complex and balanced translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Ring chromosome 4 as the sole cytogenetic anomaly in a chondroblastoma: a case report and review of the literature.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Significance of abnormalities of chromosomes 5 and 8 in chondroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Prognostic factors and outcome of pelvic, sacral, and spinal chondrosarcomas: a center-based study of 69 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic and molecular cytogenetic techniques in orthopaedic surgery.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic aberrations and their prognostic impact in chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clinical significance of genetic imbalances revealed by comparative genomic hybridization in chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Prognostic factors in chondrosarcoma: a comparative study of cellular DNA content and clinicopathologic features

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cartilaginous tumors: prognostic applications of cytophotometric DNA analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondrosarcoma of bone. A clinical and DNA flow cytometric study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

DNA flow cytometric analysis of chest-wall chondroma and chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The use of flow cytometry in assessing malignancy in bone and soft tissue tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

What's new in musculoskeletal tumor surgery

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https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

High quality RNA isolation from tumours with low cellularity and high extracellular matrix component for cDNA microarrays: application to chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

p53 expression and its relationship to DNA alterations in bone and soft tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

p53 expression and DNA ploidy of cartilage lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

p53 expression in dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Prognostic significance of Ki67 (MIB1) proliferation index and p53 over-expression in chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Altered p53 is associated with aggressive behavior of chondrosarcoma: a long term follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

p53 mutations in chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Loss of heterozygosity in the retinoblastoma tumor suppressor gene in skull base chordomas and chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clonal chromosome abnormalities in enchondromas and chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Changes of the p16 gene but not the p53 gene in human chondrosarcoma tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Changes in p14(ARF) do not play a primary role in human chondrosarcoma tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

PTEN mutation is rare in chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

H-ras oncogene mutation in dedifferentiated chondrosarcoma: polymerase chain reaction-restriction fragment length polymorphism analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Amplification of c-myc oncogene and absence of c-Ha-ras point mutation in human bone sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Abl expression in human fetal and adult tissues, tumours, and tumour microvessels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Abl expression, tumour grade, and apoptosis in chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

c-met proto-oncogene expression in benign and malignant human prostate tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clinicopathologic correlations and short-term prognosis in musculoskeletal sarcoma with c-myc oncogene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Immunohistochemical detection of c-fos and c-jun expression in osseous and cartilaginous tumours of the skeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Overexpression of cathepsin B and urokinase plasminogen activator is associated with increased risk of recurrence and metastasis in patients with chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Matrix metalloproteinase digestion of aggrecan in human cartilage tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Specific loss of chondromodulin-I gene expression in chondrosarcoma and the suppression of tumor angiogenesis and growth by its recombinant protein in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Platelet-derived growth factor-alpha receptor expression supports the growth of conventional chondrosarcoma and is associated with adverse outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

P-glycoprotein expression in cartilaginous tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

MDR1 gene expression: evaluation of its use as a molecular marker for prognosis and chemotherapy of bone and soft tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of connective tissue growth factor in cartilaginous tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of plasminogen activators and plasminogen activator inhibitor 1 in dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Microvasculature and VEGF expression in cartilaginous tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of E-cadherin in bone and soft tissue sarcomas: a possible role in epithelial differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Co-expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in cartilaginous tumours: a marker for malignancy?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Microsatellite instability in sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Comparison of cytogenetics, interphase cytogenetics, and DNA flow cytometry in bone tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Characterization of the 17p amplicon in human sarcomas: Microsatellite marker analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Prognostic relevance of cell biologic and biochemical features in conventional chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Telomerase activity in skeletal sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Is dedifferentiated chondrosarcoma a 'de-differentiated' chondrosarcoma?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A common cytogenetic abnormality and DNA content alterations in dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic findings in 19 malignant bone tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Dedifferentiated chondrosarcoma with t(9;22)(q34;q11-12)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic analysis of dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A mesenchymal chondrosarcoma of a child with the reciprocal translocation (11;22)(q24;q12)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Mesenchymal chondrosarcoma. A cytogenetic, immunohistochemical and ultrastructural study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

t(4;19)(q35;q13.1): a recurrent change in primitive mesenchymal tumors?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Translocation der(13;21)(q10;q10) in skeletal and extraskeletal mesenchymal chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Dedifferentiated clear cell chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clear cell chondrosarcoma: a pathological and immunohistochemical study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondrosarcoma of the base of the skull: a clinicopathologic study of 200 cases with emphasis on its distinction from chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic and flow cytometric analysis of a clear cell chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Low-grade myxoid chondrosarcoma of the base of the skull: CT, MR, and histopathology

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Myxoid chondrosarcoma (chordoid sarcoma) of bone: a report of two cases and review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Fusion of the EWS gene to a DNA segment from 9q22-31 in a human myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Translocations involving chromosomes 2 and 13 in benign and malignant cartilaginous neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosome aberrations and cytogenetic intratumor heterogeneity in chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Molecular analysis of a myxoid chondrosarcoma with rearrangements of chromosomes 10 and 22.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal and Skeletal Myxoid Chondrosarcoma: A Multiparameter Analysis of Three Cases Including Cytogenetic Analysis and Fluorescence In Situ Hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma: a reappraisal of its morphologic spectrum and prognostic factors based on 117 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal Myxoid Chondrosarcoma with Rhabdoid Features, with Special Reference to Its Aggressive Behavior.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondrosarcoma of the phalanx: a locally aggressive lesion with minimal metastatic potential: a report of 35 cases and a review of the literature.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of the intermediate filament peripherin in extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Nonrandom translocation in extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Recurrent breakpoints at 9q31 and 22q12.2 in extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetics as a tool in the histologic subclassification of chondrosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Translocation (9;22)(q22;q12). A recurrent chromosome abnormality in extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Translocation t(9;22)(q22;q12) is a primary cytogenetic abnormality in extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The EWS/TEC fusion protein encoded by the t(9;22) chromosomal translocation in human chondrosarcomas is a highly potent transcriptional activator

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma arising in the finger

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma: multimodal diagnosis and identification of a new cytogenetic subgroup characterized by t(9;17)(q22;q11)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Localization of the human HTF4 transcription factors 4 gene (TCF12) to chromosome 15q21

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

HTF4: a new human helix-loop-helix protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

The nucleotide sequence of the human transcription factor HTF4a cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

bHLH transcription factors and mammalian neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Muscle differentiation: more complexity to the network of myogenic regulators.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Structure and expression of the mouse gene encoding the orphan nuclear receptor TEC

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Fusion genes in solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

TLS (Translocated-in-Liposarcoma) Is a High-Affinity Interactor for Steroid, Thyroid Hormone, and Retinoid Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Association of SARFH (sarcoma-associated RNA-binding fly homolog) with regions of chromatin transcribed by RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Novel translocation (9;12)(q22;q24) in secondary chondrosarcoma arising from hereditary multiple exostosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Der(16)t(1;16)(q21;q13) as a secondary structural aberration in yet a third sarcoma, extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Matrix gene expression analysis and cellular phenotyping in chordoma reveals focal differentiation pattern of neoplastic cells mimicking nucleus pulposus development

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Does chondroid chordoma exist?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chondroid chordoma. A hyalinized chordoma without cartilaginous differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Keratin subsets and monoclonal antibody HBME-1 in chordoma: immunohistochemical differential diagnosis between tumors simulating chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chordomas and cartilaginous tumors at the skull base

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Expression of cathepsin K in chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

CARTILAGE TUMORS IN SOFT TISSUES, PARTICULARLY IN THE HAND AND FOOT

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chordoma: a cytologic study with histologic and radiologic correlation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Immunohistochemical analysis of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin, and neural cell adhesion molecule (NCAM) in chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic, telomere, and telomerase studies in five surgically managed lumbosacral chordomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic investigation of chordomas of the skull

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic Studies of Pediatric Brain and Spinal Cord Tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic analysis of two sacral chordomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clonal chromosome aberrations in three sacral chordomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

First cytogenetic study of a recurrent familial chordoma of the clivus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

A tumor suppressor locus in familial and sporadic chordoma maps to 1p36

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Identification of isochromosome 1q as a recurring chromosome aberration in skull base chordomas: a new marker for aggressive tumors?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetics of sacral chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosomal abnormalities in two chordomas

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic and molecular cytogenetic analysis of sacral chordoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Parachordoma: a new clinicopathologic entity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Mixed tumors of the skin of the salivary gland type

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Parachordoma: a rare sarcoma with clonal chromosomal changes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic analysis of a parachordoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic study of 249 consecutive patients examined for a bone tumor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Frequent clonal chromosomal changes in human non-malignant tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosome rearrangements in synovial chondromatous lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Involvement of chromosomes 6 and 11 in a soft tissue chondroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Supernumerary ring chromosomes derived from the long arm of chromosome 12 as the primary cytogenetic anomaly in a rare soft tissue chondroma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosome 6 abnormalities are recurrent in synovial chondromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosomal rearrangements in chondromatous tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Solitary enchondroma with clonal chromosomal abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Synovial chondromatosis: clonal chromosome changes provide further evidence for a neoplastic disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosomal abnormalities in low grade chondrosarcoma and a review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Clonal chromosome aberrations with monosomy of chromosome 8 in a case of grade III chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic findings in a case of dedifferentiated chondrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Cytogenetic study of extraskeletal mesenchymal chondrosarcoma. A case report

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Chromosomal Abnormality T(9;22)(Q22;Q12) In an Extraskeletal Myxoid Chondrosarcoma Characterized By Fine Needle Aspiration Cytology, Electron Microscopy, Immunohistochemistry and Dna Flow Cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma-cytogenetic, molecular genetic, and cDNA microarray analyses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-4608%2803%2900002-5

7 January 2021

10.1016/S0165-4608(03)00002-5

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12742153