The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate (Q28284035)

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F Tufaro

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C McCormick

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U Lindahl

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K Lidholt

Journal of Biological Chemistry

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language of work or name

English

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publication date

9 October 1998

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published in

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volume

273

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page(s)

26265-8

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issue

41

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cites work

A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis

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A gene for hereditary multiple exostoses maps to chromosome 19p.

21 January 2018

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Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11

21 January 2018

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Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)

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https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

21 January 2018

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The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

21 January 2018

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Hereditary multiple exostoses.

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Natural history study of hereditary multiple exostoses

21 January 2018

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The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Positional cloning of a gene involved in hereditary multiple exostoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Biosynthesis of heparin. The D-glucuronosyl- and N-acetyl-D-glucosaminyltransferase reactions and their relation to polymer modification

21 January 2018

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Basement-membrane heparan sulphate with high affinity for antithrombin synthesized by normal and transformed mouse mammary epithelial cells

21 January 2018

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Structural differences between heparan sulphates of proteoglycan involved in the formation of basement membranes in vivo by Lewis-lung-carcinoma-derived cloned cells with different metastatic potentials

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Selective reduction of 6-O-sulfation in heparan sulfate from transformed mammary epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Regulated diversity of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.41.26265

Expression of the mouse mastocytoma glucosaminyl N-deacetylase/ N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate

21 January 2018

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