Epigenetic Changes: Potential Therapeutic Targets (Q35118544)

6 August 2017

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title

Epigenetic changes: potential therapeutic targets (English)

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6 August 2017

Epigenetic Changes: Potential Therapeutic Targets (English)

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

history and philosophy of science

29 December 2023

main subject

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

29 December 2023

author name string

Thea Kalebic

1

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6 August 2017

language of work or name

English

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publication date

1 March 2003

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full work available at URL

6 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.2003.tb05982.x

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.2003.tb05982.x

29 December 2023

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Annals of the New York Academy of Sciences

29 December 2023

published in

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6 August 2017

983

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6 August 2017

278-285

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The DNA methylation system in proliferating and differentiated cells

6 August 2017

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05982.X

Participation of histones and histone-modifying enzymes in cell functions through alterations in chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05982.X

Towards a pharmacology of DNA methylation

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone deacetylases and cancer: causes and therapies

29 December 2023

2

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone acetylation and disease

29 December 2023

3

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Epigenomics and epigenetic therapy of cancer

29 December 2023

4

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promise

29 December 2023

6

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

29 December 2023

7

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Promoter-region hypermethylation and gene silencing in human cancer

29 December 2023

8

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation

29 December 2023

9

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.

29 December 2023

10

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNA methylation, methyltransferases, and cancer

29 December 2023

11

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

29 December 2023

12

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

29 December 2023

13

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Rb interacts with histone deacetylase to repress transcription

29 December 2023

14

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

29 December 2023

15

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNA methylation: past, present and future directions

29 December 2023

17

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Altered DNA methylation: a secondary mechanism involved in carcinogenesis

29 December 2023

18

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

29 December 2023

19

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

29 December 2023

21

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

29 December 2023

22

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Ara-C treatment leads to differentiation and reverses the transformed phenotype in a human rhabdomyosarcoma cell line

29 December 2023

24

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

29 December 2023

Methylation matters

25

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

29 December 2023

26

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

DNA methylation and cancer

29 December 2023

27

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Reduced methyl group acceptance of 1-beta-D-arabinofuranosylcytosine-containing DNA polymers

29 December 2023

30

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Effects of 5-azacytidine and its 2'-deoxyderivative on cell differentiation and DNA methylation

29 December 2023

31

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy

29 December 2023

33

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance

29 December 2023

34

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

29 December 2023

35

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas

29 December 2023

36

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

29 December 2023

40

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia.

29 December 2023

41

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer

29 December 2023

42

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone acetylation and cancer

29 December 2023

44

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone acetyltransferases: function, structure, and catalysis

29 December 2023

45

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

The human histone deacetylase family

29 December 2023

47

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

29 December 2023

48

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Cooperation between complexes that regulate chromatin structure and transcription

29 December 2023

49

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

29 December 2023

50

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

29 December 2023

51

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

29 December 2023

52

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate.

29 December 2023

54

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

29 December 2023

56

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone deacetylase inhibitors as new cancer drugs

29 December 2023

57

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone deacetylase inhibitors: development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers.

29 December 2023

58

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

29 December 2023

59

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

29 December 2023

60

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?

29 December 2023

61

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05982.X

29 December 2023

Identifiers

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6 August 2017

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