GRK2 targeted knock-down results in spontaneous hypertension, and altered vascular GPCR signaling. (Q35104021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561731%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

GRK2 targeted knock-down results in spontaneous hypertension, and altered vascular GPCR signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561731%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

27 February 2020

main subject

0 references

author

Robert Gros

3

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27 February 2020

author name string

Elena Tutunea-Fatan

1

1 reference

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27 February 2020

Fabiana A Caetano

2

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27 February 2020

Stephen S G Ferguson

4

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27 February 2020

language of work or name

English

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publication date

5 January 2015

1 reference

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Journal of Biological Chemistry

27 February 2020

published in

1 reference

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27 February 2020

volume

290

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27 February 2020

issue

8

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27 February 2020

page(s)

5141-5155

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β-adrenoceptors as molecular targets in the treatment of hypertension

27 February 2020

cites work

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Refining efficacy: allosterism and bias in G protein-coupled receptor signaling.

9 July 2018

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9 July 2018

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Enhanced GRK2 expression and desensitization of betaAR vasodilatation in hypertensive patients

9 July 2018

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Regulation of GPCR signaling in hypertension

9 July 2018

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Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2.

9 July 2018

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Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands

9 July 2018

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G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans

9 July 2018

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Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction

9 July 2018

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Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration

9 July 2018

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Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas

9 July 2018

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

9 July 2018

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Phosphorylation-independent attenuation of GPCR signalling

9 July 2018

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An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

9 July 2018

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Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

9 July 2018

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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

9 July 2018

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9 July 2018

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G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression.

9 July 2018

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

9 July 2018

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Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization

9 July 2018

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G-protein-coupled receptor kinase activity is increased in hypertension

9 July 2018

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9 July 2018

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9 July 2018

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Increased nitric oxide bioavailability in adult GRK2 hemizygous mice protects against angiotensin II-induced hypertension.

9 July 2018

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Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats.

27 September 2018

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Impaired vasodilator function in hypertension: the role of alterations in receptor-G protein coupling.

27 September 2018

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Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates Ang II-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats.

27 September 2018

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Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure

27 September 2018

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Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors

27 September 2018

1 reference

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GRK2 Levels in Umbilical Arteries of Pregnancies Complicated by Gestational Hypertension and Preeclampsia

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.615658

Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells

21 January 2018

1 reference

12 December 2020

A role for MAP kinase in differentiated smooth muscle contraction evoked by alpha-adrenoceptor stimulation

1 reference

12 December 2020

Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension

1 reference

12 December 2020

G-protein-coupled receptor kinase expression in hypertension.

1 reference

12 December 2020

Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization

1 reference

12 December 2020

Effects of age, gender, and blood pressure on myogenic responses of mesenteric arteries from C57BL/6 mice

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.615658

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561731%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561731%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference