Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. (Q35088324)

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English	Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.	scientific article

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20 January 2020

Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease (English)

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20 January 2020

Alzheimer's disease

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3

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20 January 2020

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Muthuswamy Anantharaman

1

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20 January 2020

Jitbanjong Tangpong

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20 January 2020

Michael P Murphy

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20 January 2020

William R Markesbery

5

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20 January 2020

Kelley K Kiningham

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20 January 2020

Daret K St Clair

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1 May 2006

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20 January 2020

The American Journal of Pathology

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20 January 2020

168

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20 January 2020

5

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20 January 2020

1608-1618

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20 January 2020

Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

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Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?

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Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis

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8 July 2018

Proteomic identification of nitrated proteins in Alzheimer's disease brain

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8 July 2018

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

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8 July 2018

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8 July 2018

Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists.

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8 July 2018

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

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8 July 2018

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction

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Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration

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Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

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Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.

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Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

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Decreased brain protein levels of cytochrome oxidase subunits in Alzheimer's disease and in hereditary spinocerebellar ataxia disorders: a nonspecific change?

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Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice

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An activity in rat tissues that modifies nitrotyrosine-containing proteins

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

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Oxidative stress hypothesis in Alzheimer's disease

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Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4.

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.

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Evidence of neuronal oxidative damage in Alzheimer's disease.

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27 September 2018

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Proteolytic degradation of tyrosine nitrated proteins

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Identifiers

10.2353/AJPATH.2006.051223

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Europe PubMed Central

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20 January 2020

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20 January 2020

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20 January 2020

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