Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo (Q35080479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16959882%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo (English)

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29 December 2019

1

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Karin Oien

5

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29 December 2019

Carmen Guerra

8

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29 December 2019

Alan R. Clarke

11

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4

Alicia M Cole

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29 December 2019

2

Valerie Meniel

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29 December 2019

3

Julie A Wilkins

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29 December 2019

9

Gabrielle H Ashton

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29 December 2019

Victoria Marsh Durban

6

object named as

Victoria Marsh

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7

Thomas J Jamieson

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29 December 2019

author name string

Mariano Barbacid

10

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29 December 2019

language of work or name

English

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publication date

7 September 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16959882%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 December 2019

published in

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29 December 2019

volume

103

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29 December 2019

issue

38

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29 December 2019

page(s)

14122-14127

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APC inhibits ERK pathway activation and cellular proliferation induced by RAS

29 December 2019

cites work

1 reference

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Coordinating ERK/MAPK signalling through scaffolds and inhibitors

8 July 2018

1 reference

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The Akt-mTOR tango and its relevance to cancer

8 July 2018

1 reference

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EphB receptor activity suppresses colorectal cancer progression

8 July 2018

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

8 July 2018

1 reference

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Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

8 July 2018

1 reference

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Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

8 July 2018

1 reference

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Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

8 July 2018

1 reference

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Linking colorectal cancer to Wnt signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Bi-transgenic mice reveal that K-rasVal12 augments a p53-independent apoptosis when small intestinal villus enterocytes reenter the cell cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Lessons from hereditary colorectal cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Identification of FAP locus genes from chromosome 5q21

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

RAS oncogenes: the first 30 years.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604130103

Apc deficiency predisposes to renal carcinoma in the mouse

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599922

Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16959882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0604130103

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29 December 2019

0 references

1 reference

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29 December 2019

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