Role of PARP under stress conditions: cell death or protection? (Q35074264)

6 August 2017

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title

Role of PARP under stress conditions: cell death or protection? (English)

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6 August 2017

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Vincenzo Giuseppe Nicoletti

series ordinal

1

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PubMed ID

12608693

6 August 2017

Anna Maria Giuffrida Stella

series ordinal

2

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6 August 2017

1 February 2003

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6 August 2017

Neurochemical Research

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6 August 2017

28

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6 August 2017

2

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6 August 2017

187-194

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https://scigraph.springernature.com/pub.10.1023/a:1022316914492

6 August 2017

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cites work

Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.

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12 December 2020

A role of the Ca2+/Mg2+-dependent endonuclease in apoptosis and its inhibition by Poly(ADP-ribose) polymerase

1 reference

12 December 2020

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

1 reference

12 December 2020

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

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12 December 2020

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

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12 December 2020

Nitric oxide synthase induction in astroglial cell cultures: effect on heat shock protein 70 synthesis and oxidant/antioxidant balance

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12 December 2020

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

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12 December 2020

The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase

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12 December 2020

Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia

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12 December 2020

Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells

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12 December 2020

Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.

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12 December 2020

Induction of nitric oxide synthase in L929 cells by tumour-necrosis factor α is prevented by inhibitors of poly(ADP-ribose) polymerase

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12 December 2020

Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

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12 December 2020

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

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12 December 2020

Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures.

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12 December 2020

Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.

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12 December 2020

BRCT domain interactions in the heterodimeric DNA repair protein XRCC1-DNA ligase III

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12 December 2020

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

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12 December 2020

Molecular interactions between poly(ADP-ribose) polymerase (PARP I) and topoisomerase I (Topo I): identification of topology of binding

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12 December 2020

Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.

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12 December 2020

Poly(ADP-ribose) polymerase (PARP) revisited. A new role for an old enzyme: PARP involvement in neurodegeneration and PARP inhibitors as possible neuroprotective agents.

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12 December 2020

Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells

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12 December 2020

A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues

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12 December 2020

Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis

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12 December 2020

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

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12 December 2020

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

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12 December 2020

Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase

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12 December 2020

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

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12 December 2020

Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation

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12 December 2020

A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation

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12 December 2020

Modification of growth related enzymatic pathways and apparent loss of tumorigenicity of a ras-transformed bovine endothelial cell line by treatment with 5-iodo-6-amino-1,2-benzopyrone (INH2BP).

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12 December 2020

DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite

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12 December 2020

Reduction of the DNA base excision repair protein, XRCC1, may contribute to DNA fragmentation after cold injury-induced brain trauma in mice

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12 December 2020

Poly(ADP-ribose) in the cellular response to DNA damage

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12 December 2020

Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells.

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12 December 2020

3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock

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12 December 2020

A p53-dependent mouse spindle checkpoint

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12 December 2020

Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

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12 December 2020

Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1.

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12 December 2020

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease.

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12 December 2020

Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

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12 December 2020

Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors

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12 December 2020

Abnormal centrosome amplification in the absence of p53.

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12 December 2020

The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia

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12 December 2020

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

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12 December 2020

Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione

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12 December 2020

Dissection of ADP-ribose polymer synthesis into individual steps of initiation, elongation, and branching

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12 December 2020

Tankyrase promotes telomere elongation in human cells

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12 December 2020

DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines

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12 December 2020

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

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12 December 2020

Survival and proliferation of cells expressing caspase-uncleavable Poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent

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12 December 2020

The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex

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12 December 2020

Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents

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12 December 2020

Poly(ADP-ribose) synthetase activation: an early indicator of neurotoxic DNA damage

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12 December 2020

Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission

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12 December 2020

Domain specific interaction in the XRCC1-DNA polymerase beta complex

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12 December 2020

Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences.

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12 December 2020

The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function

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12 December 2020

Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide

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12 December 2020

Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14

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12 December 2020

Association of poly(adenosine diphosphate ribosylated) nucleosomes with transcriptionally active and inactive regions of chromatin

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12 December 2020

Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase

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12 December 2020

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

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12 December 2020

Poly (ADP-ribose) polymerase induction is an early signal of apoptosis in human neuroblastoma.

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12 December 2020

Poly(ADP-ribose) polymerase-1 in the nervous system

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12 December 2020

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

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12 December 2020

The response of Parp knockout mice against DNA damaging agents.

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12 December 2020

PARP is important for genomic stability but dispensable in apoptosis

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12 December 2020

Regulation of RNA polymerase II-dependent transcription by poly(ADP-ribosyl)ation of transcription factors

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12 December 2020

Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation

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12 December 2020

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

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12 December 2020

Identifiers

DOI

10.1023/A:1022316914492

1 reference

PubMed ID

12608693

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12608693