Hepatic T cells and liver tolerance (Q35038298)

5 August 2017

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title

Hepatic T cells and liver tolerance (English)

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5 August 2017

Ian Nicholas Crispe

1

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5 August 2017

1 January 2003

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Nature Reviews Immunology

5 August 2017

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5 August 2017

3

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5 August 2017

51-62

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5 August 2017

1

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Enterotropic mouse hepatitis virus

5 August 2017

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The protective role of cytotoxic T cells and interferon against coronavirus invasion of the brain

31 March 2020

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Development of immunity to malaria may not be an entirely active process

31 March 2020

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The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response.

31 March 2020

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Induction of immunological tolerance by porcine liver allografts.

31 March 2020

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A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

31 March 2020

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Metabolic substrates can alter postischemic recovery in preconditioned ischemic heart

31 March 2020

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Modulation of cell surface expression of liver carbohydrate receptors during in vivo induction of apoptosis with lead nitrate

31 March 2020

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Lymphocyte suppression by Kupffer cells prevents portal venous tolerance induction: a study of macrophage function after intravenous gadolinium

31 March 2020

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Resident human hepatitis lymphocytes are phenotypically different from circulating lymphocytes

31 March 2020

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Strange brew: T cells in the liver

31 March 2020

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Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver

31 March 2020

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Immunomodulatory effects of the liver: deletion of activated CD4+ effector cells and suppression of IFN-gamma-producing cells after intravenous protein immunization

31 March 2020

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Proliferation and apoptosis of B220+CD4-CD8-TCR alpha beta intermediate T cells in the liver of normal adult mice: implication for lpr pathogenesis

31 March 2020

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Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand

31 March 2020

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The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo

31 March 2020

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Large granular lymphocytes or "pit cells" from rat liver: isolation, ultrastructural characterization and natural killer activity

31 March 2020

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Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection

31 March 2020

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NK cells cause liver injury and facilitate the induction of T cell-mediated immunity to a viral liver infection

31 March 2020

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Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1alpha (MIP-1alpha)-dependent pathways

31 March 2020

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Time course profile and cell-type-specific production of monokine induced by interferon-gamma in Concanavalin A-induced hepatic injury in mice: comparative study with interferon-inducible protein-10.

31 March 2020

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Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression

31 March 2020

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Development and selection of NKT cells

31 March 2020

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Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection

31 March 2020

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Evidence for extrathymic generation of intermediate T cell receptor cells in the liver revealed in thymectomized, irradiated mice subjected to bone marrow transplantation

31 March 2020

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NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells

31 March 2020

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Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells.

31 March 2020

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Mouse γδ TCR+NK1.1+ thymocytes specifically produce interleukin-4, are major histocompatibility complex class I independent, and are developmentally related to αβ TCR+NK1.1+ thymocytes

31 March 2020

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Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice.

31 March 2020

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NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

31 March 2020

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Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis

31 March 2020

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Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi

31 March 2020

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Treatment with alpha-galactosylceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive

31 March 2020

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During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein

31 March 2020

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CD1d-restricted NK T cells are dispensable for specific antibody responses and protective immunity against liver stage malaria infection in mice.

31 March 2020

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Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells

31 March 2020

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Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

31 March 2020

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A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas

31 March 2020

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

31 March 2020

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alpha -galactosylceramide-activated Valpha 14 natural killer T cells mediate protection against murine malaria

31 March 2020

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Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

31 March 2020

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Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T cell receptor bearing cells

31 March 2020

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RAG1, RAG2 and pre-T cell receptor alpha chain expression by adult human hepatic T cells: evidence for extrathymic T cell maturation

31 March 2020

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In vitro evidence for the presence of hematopoietic stem cells in the adult human liver.

31 March 2020

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Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage

31 March 2020

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Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation

31 March 2020

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Flow cytometry CD4+/CD8+ ratio of liver-derived lymphocytes correlates with viral replication in chronic hepatitis B.

31 March 2020

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Characterization of liver T-cell receptor gammadelta T cells obtained from individuals chronically infected with hepatitis C virus (HCV): evidence for these T cells playing a role in the liver pathology associated with HCV infections

31 March 2020

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The liver as a site of T-cell apoptosis: graveyard, or killing field?

31 March 2020

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Hepatic expression of intercellular adhesion molecule-1 (ICAM-1) in viral hepatitis B.

31 March 2020

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Vascular adhesion molecule expression in viral chronic hepatitis: evidence of neoangiogenesis in portal tracts.

31 March 2020

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B7/BB-1 expression and hepatitis activity in liver tissues of patients with chronic hepatitis C.

31 March 2020

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Lymphocyte trafficking and regional immunity.

31 March 2020

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A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature

31 March 2020

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Vascular adhesion protein 1 mediates binding of T cells to human hepatic endothelium

31 March 2020

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Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice

31 March 2020

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Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation

31 March 2020

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Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo

31 March 2020

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A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph

31 March 2020

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Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites

31 March 2020

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Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease

31 March 2020

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Characterization of interstitial dendritic cells in human liver

31 March 2020

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Development of CD8 -Positive Dendritic Cells from a Common Myeloid Progenitor

31 March 2020

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Phenotypic and functional characterization of mouse hepatic CD8 alpha+ lymphoid-related dendritic cells

31 March 2020

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Kupffer cell-mediated recruitment of rat dendritic cells to the liver: roles of N-acetylgalactosamine-specific sugar receptors

31 March 2020

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Asialoglycoprotein receptors on rat dendritic cells: possible roles for binding with Kupffer cells and ingesting virus particles

31 March 2020

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The macrophage C-type lectin specific for galactose/N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells

31 March 2020

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Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

31 March 2020

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Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

31 March 2020

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Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells

31 March 2020

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Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells

31 March 2020

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

31 March 2020

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Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure.

31 March 2020

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Preferential localization of effector memory cells in nonlymphoid tissue

31 March 2020

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Visualizing the generation of memory CD4 T cells in the whole body

31 March 2020

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Antigen-specific primary activation of CD8+ T cells within the liver

31 March 2020

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Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival

31 March 2020

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Death by neglect as a deletional mechanism of peripheral tolerance

31 March 2020

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Apoptosis of alloreactive T cells in liver allografts during tolerance induction

31 March 2020

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Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

31 March 2020

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The central effectors of cell death in the immune system

31 March 2020

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Serial killers: ordering caspase activation events in apoptosis

31 March 2020

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

31 March 2020

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Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.

31 March 2020

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Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes

31 March 2020

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

31 March 2020

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Hepatocytes and liver nonparenchymal cells induce apoptosis in activated T cells

31 March 2020

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Costimulation blockade promotes the apoptotic death of graft-infiltrating T cells and prolongs survival of hepatic allografts from FLT3L-treated donors

31 March 2020

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Fas-mediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver

31 March 2020

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Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells

31 March 2020

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Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

31 March 2020

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Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys

31 March 2020

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Mammalian and viral IL-10 enhance C-C chemokine receptor 5 but down-regulate C-C chemokine receptor 7 expression by myeloid dendritic cells: impact on chemotactic responses and in vivo homing ability

31 March 2020

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Mechanisms of tolerance induction after rat liver transplantation: intrahepatic CD4(+) T cells produce different cytokines during rejection and tolerance in response to stimulation

31 March 2020

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

31 March 2020

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IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

31 March 2020

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Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

31 March 2020

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Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells

31 March 2020

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Transcriptional reprogramming of dendritic cells by differentiation stimuli

31 March 2020

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Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells

31 March 2020

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Natural interferon alpha/beta-producing cells link innate and adaptive immunity

31 March 2020

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Lethal effect of the anti-Fas antibody in mice

31 March 2020

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Induction of murine hepatocyte death by membrane-bound CD95 (Fas/APO-1)-ligand: characterization of an in vitro system

31 March 2020

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Reduced-size hepatic allografts

31 March 2020

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T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium

31 March 2020

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Modulation of epithelial cell growth by intraepithelial gamma delta T cells

31 March 2020

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FK506 promotes liver regeneration by suppressing natural killer cell activity

31 March 2020

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Molecular mechanisms of augmenter of liver regeneration as immunoregulator: its effect on interferon-gamma expression in rat liver

31 March 2020

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Liver damage preferentially results from CD8(+) T cells triggered by high affinity peptide antigens

31 March 2020

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Liver damage by infiltrating CD8+ T cells is Fas dependent

31 March 2020

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Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis

31 March 2020

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Essential roles of the Fas ligand in the development of hepatitis

31 March 2020

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CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection

31 March 2020

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Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome

31 March 2020

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CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

31 March 2020

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Analysis of successful immune responses in persons infected with hepatitis C virus

31 March 2020

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Analysis of a successful immune response against hepatitis C virus

31 March 2020

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Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant

31 March 2020

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The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

31 March 2020

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Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

31 March 2020

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

31 March 2020

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Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

31 March 2020

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Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway

31 March 2020

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The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line

31 March 2020

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Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

31 March 2020

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Hepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection

31 March 2020

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A T cell-dependent experimental liver injury in mice inducible by concanavalin A

31 March 2020

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Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver

31 March 2020

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Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

31 March 2020

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Immune response to hepatitis A virus capsid proteins after infection

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Accessory function of Kupffer cells in the antigen-specific blastogenic response of an L3T4+ T-lymphocyte clone to Listeria monocytogenes

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

A thymic precursor to the NK T cell lineage

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI981

1 reference

5 August 2017

1 reference

PubMed ID

12511875