Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death (Q35024449)

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English	Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death (English)

1 reference

Europe PubMed Central

5 August 2017

1 reference

based on heuristic

inferred from title

multicellularity

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Jayashree C Jagtap

1

1 reference

Europe PubMed Central

5 August 2017

D Parveen

2

1 reference

Europe PubMed Central

5 August 2017

Reecha D Shah

3

1 reference

Europe PubMed Central

5 August 2017

Aarti Desai

4

1 reference

Europe PubMed Central

5 August 2017

Dipali Bhosale

5

1 reference

Europe PubMed Central

5 August 2017

Ashish Chugh

6

1 reference

Europe PubMed Central

5 August 2017

Deepak Ranade

7

1 reference

Europe PubMed Central

5 August 2017

Swapnil Karnik

8

1 reference

Europe PubMed Central

5 August 2017

Bhushan Khedkar

9

1 reference

Europe PubMed Central

5 August 2017

Aaishwarya Mathur

10

1 reference

Europe PubMed Central

5 August 2017

Kumar Natesh

11

1 reference

Europe PubMed Central

5 August 2017

Goparaju Chandrika

12

1 reference

Europe PubMed Central

5 August 2017

Padma Shastry

13

1 reference

Europe PubMed Central

5 August 2017

publication date

21 November 2014

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

5

1 reference

Europe PubMed Central

5 August 2017

8-19

1 reference

Europe PubMed Central

5 August 2017

The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Glioblastoma multiforme: State of the art and future therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

HKH40A downregulates GRP78/BiP expression in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Expression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Role of prostate apoptosis response 4 in translocation of GRP78 from the endoplasmic reticulum to the cell surface of trophoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Tamoxifen reduces P-gp-mediated multidrug resistance via inhibiting the PI3K/Akt signaling pathway in ER-negative human gastric cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Novel mechanism of apoptosis resistance in cancer mediated by extracellular PAR-4

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Three-dimensional cell culture: the missing link in drug discovery

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

A novel MMP-2 inhibitor 3-azidowithaferin A (3-azidoWA) abrogates cancer cell invasion and angiogenesis by modulating extracellular Par-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3β/β-catenin signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

3D cell culture: a review of current approaches and techniques

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

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8 July 2018

Glutathione transferases and development of new principles to overcome drug resistance

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8 July 2018

Cancer-selective apoptotic effects of extracellular and intracellular Par-4.

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8 July 2018

Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.

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8 July 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

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8 July 2018

Drug resistance and the solid tumor microenvironment

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8 July 2018

Downregulation of PAR-4, a pro-apoptotic gene, in pancreatic tumors harboring K-ras mutation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

EGFR associated expression profiles vary with breast tumor subtype

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309838

8 July 2018

Glucose regulated proteins in cancer progression, drug resistance and immunotherapy

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8 July 2018

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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8 July 2018

Stress induction of GRP78/BiP and its role in cancer.

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8 July 2018

Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells.

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8 July 2018

The use of 3-D cultures for high-throughput screening: the multicellular spheroid model

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Microscale tissue engineering using gravity-enforced cell assembly

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Current chemotherapy for glioblastoma.

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8 July 2018

Par-4, a pro-apoptotic gene, inhibits radiation-induced NF kappa B activity and Bcl-2 expression leading to induction of radiosensitivity in human prostate cancer cells PC-3.

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Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies

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8 July 2018

Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression

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Multicellular resistance: a paradigm for clinical resistance?

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Temozolomide and treatment of malignant glioma.

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Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders

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Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4.

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Expression and function of the leucine zipper protein Par-4 in apoptosis

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The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

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Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells.

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The identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon, and zeta

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Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis.

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21 January 2018

Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer.

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21 January 2018

Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas

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Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.

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Inactivation of the Candidate Tumor Suppressor Par-4 in Endometrial Cancer

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Mechanisms of drug sensitivity and resistance in cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis mediated by a novel leucine zipper protein Par-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/25685660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostate apoptosis response gene-4 sensitizes neoplastic lymphocytes to CD95-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25685660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25685660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25685660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FOB.2014.11.005

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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