The amyloid hypothesis: let sleeping dogmas lie? (Q35019455)

5 August 2017

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title

The amyloid hypothesis: let sleeping dogmas lie? (English)

1 reference

5 August 2017

Glenda M Bishop

1

1 reference

PubMed ID

12470810

5 August 2017

Stephen R Robinson

series ordinal

2

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5 August 2017

1 November 2002

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5 August 2017

Neurobiology of Aging

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5 August 2017

23

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5 August 2017

6

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5 August 2017

1101-1105

1 reference

Alzheimer's disease and Alzheimer's dementia: distinct but overlapping entities.

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Nerve inflammation halts trial for Alzheimer's drug.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

The relative frequency of "dementia of unknown etiology" increases with age and is nearly 50% in nonagenarians

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Perivascular astrocytes within Alzheimer's disease plaques

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Pro-inflammatory complement activation by the A beta peptide of Alzheimer's disease is biologically significant and can be blocked by vaccinia virus complement control protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Testing times for the "amyloid cascade hypothesis".

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Abeta conformational change is central to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Copernicus revisited: amyloid beta in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

The blood-brain barrier and cerebrovascular pathology in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Alzheimer's vaccine: a cure as dangerous as the disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Amyloid-beta: a (life) preserver for the brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

1 reference

7 January 2021

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Changes in the cellular distribution of glutamine synthetase in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Complement activation by beta-amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Suicide and Alzheimer's pathology in the elderly: a case-control study.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Low cerebrospinal fluid beta-amyloid 42 in patients with acute bacterial meningitis and normalization after treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Arson. Tracking the culprit in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Glial diffusion barriers during aging and pathological states

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Diffusion constraints and neuron-glia interaction during aging.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Bioflocculant hypothesis: a partial endorsement.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

Evolution and the scientific method.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

The pathogenesis of Alzheimer's disease. Is amyloid beta-protein the beginning or the end?

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900050-7

7 January 2021

10.1016/S0197-4580(02)00050-7

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12470810