Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis (Q34998273)

5 August 2017

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis (English)

1 reference

genome-wide association study

5 August 2017

0 references

Jakob Begun

15

0 references

Jonas Halfvarson

Jonas Halfvarson

20

0 references

Richard Duerr

Richard H Duerr

19

0 references

Mauro D'Amato

Mauro D'Amato

31

0 references

John D. Rioux

John D Rioux

37

0 references

Mark Joseph Daly

36

Mark J Daly

1 reference

5 August 2017

21

Dermot P B McGovern

1 reference

5 August 2017

27

Rinse K Weersma

1 reference

5 August 2017

35

Ramnik J Xavier

1 reference

5 August 2017

26

Mark S Silverberg

1 reference

5 August 2017

32

Severine Vermeire

1 reference

5 August 2017

23

Stefan Schreiber

1 reference

5 August 2017

18

Judy H Cho

1 reference

5 August 2017

33

Andre Franke

1 reference

5 August 2017

24

Philip L Schumm

1 reference

5 August 2017

Graham L Radford-Smith

22

Graham Radford-Smith

1 reference

5 August 2017

14

Alain Bitton

1 reference

5 August 2017

13

Vito Annese

1 reference

5 August 2017

25

Yashoda Sharma

1 reference

5 August 2017

3

Gabrielle Boucher

1 reference

5 August 2017

1

Mélissa Beaudoin

1 reference

5 August 2017

6

Christine Stevens

1 reference

5 August 2017

12

Caroline Lagacé

1 reference

5 August 2017

10

Leif Törkvist

1 reference

5 August 2017

34

Guillaume Lettre

1 reference

International IBD Genetics Consortium

5 August 2017

30

International IBD Genetics Consortium

1 reference

NIDDK IBD Genetics Consortium

5 August 2017

29

NIDDK IBD Genetics Consortium

1 reference

5 August 2017

16

Steve R Brant

1 reference

5 August 2017

Philippe Goyette

2

1 reference

5 August 2017

Manuel A Rivas

5

1 reference

5 August 2017

Azadeh Alikashani

7

1 reference

5 August 2017

Martin Ladouceur

8

1 reference

5 August 2017

David Ellinghaus

9

1 reference

5 August 2017

Gautam Goel

11

1 reference

5 August 2017

Francesca Bresso

17

1 reference

5 August 2017

Quebec IBD Genetics Consortium

28

1 reference

5 August 2017

Ken Sin Lo

4

1 reference

5 August 2017

language of work or name

1 reference

12 September 2013

1 reference

5 August 2017

1 reference

5 August 2017

9

1 reference

5 August 2017

e1003723

1 reference

5 August 2017

9

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

start time

12 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

1 reference

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Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

8 July 2018

1 reference

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Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance

8 July 2018

1 reference

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Transforming growth factor-β1 suppresses hepatitis B virus replication by the reduction of hepatocyte nuclear factor-4α expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

A human MAP kinase interactome

8 July 2018

1 reference

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Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Optimus Primer: A PCR enrichment primer design program for next-generation sequencing of human exonic regions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

A method and server for predicting damaging missense mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Mapping of HNF4alpha target genes in intestinal epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Identification of an inter-transcription factor regulatory network in human hepatoma cells by Matrix RNAi

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Mapping short DNA sequencing reads and calling variants using mapping quality scores

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Nuclear ubiquitin ligases, NF-kappaB degradation, and the control of inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Unravelling the pathogenesis of inflammatory bowel disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Plasticity and expanding complexity of the hepatic transcription factor network during liver development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Adaptively inferring human transcriptional subnetworks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Chemokine receptors and leukocyte trafficking in the mucosal immune system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Control of pancreas and liver gene expression by HNF transcription factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC)

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772057

Modulation of Hepatic Gene Expression by Hepatocyte Nuclear Factor 1

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24068945

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24068945

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1003723

1 reference

5 August 2017

1 reference

5 August 2017

1 reference