Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin (Q34990436)

5 August 2017

Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin (English)

1 reference

5 August 2017

1 reference

Rita Slaaby

1

1 reference

PubMed ID

25604425

5 August 2017

language of work or name

English

0 references

publication date

21 January 2015

1 reference

5 August 2017

1 reference

5 August 2017

5

1 reference

5 August 2017

7911

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

5 August 2017

start time

21 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep07911

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cites work

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Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

8 July 2018

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Changing the way we think about endothelial cell insulin sensitivity, nitric oxide, and the pathophysiology of type 2 diabetes: the FoxO is loose

8 July 2018

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The role of insulin and IGF system in pancreatic cancer

8 July 2018

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The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium

8 July 2018

1 reference

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Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

8 July 2018

1 reference

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Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

8 July 2018

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IMC-A12, a human IgG1 monoclonal antibody to the insulin-like growth factor I receptor

8 July 2018

1 reference

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Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

8 July 2018

1 reference

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Structure of the insulin receptor ectodomain reveals a folded-over conformation

8 July 2018

1 reference

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Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant

8 July 2018

1 reference

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Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.

8 July 2018

1 reference

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The insulin-like growth factor system and cancer

8 July 2018

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Structural biology of insulin and IGF1 receptors: implications for drug design

8 July 2018

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

8 July 2018

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

8 July 2018

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Structure and function of the type 1 insulin-like growth factor receptor.

8 July 2018

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Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

8 July 2018

1 reference

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Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects

8 July 2018

1 reference

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Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

8 July 2018

1 reference

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Functionally distinct insulin receptors generated by tissue-specific alternative splicing

8 July 2018

1 reference

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A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity

8 July 2018

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Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes

8 July 2018

1 reference

Insulin/IGF-1 hybrid receptor expression on human platelets: consequences for the effect of insulin on platelet function

21 January 2018

1 reference

Glucosamine Induces Resistance to Insulin-Like Growth Factor I (IGF-I) and Insulin in Hep G2 Cell Cultures: Biological Significance of IGF-I/Insulin Hybrid Receptors

21 January 2018

1 reference

Insulin and IGF1 receptors in human cardiac microvascular endothelial cells: metabolic, mitogenic and anti-inflammatory effects.

21 January 2018

1 reference

Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25604425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25604425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25604425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP07911

1 reference

PubMed ID

25604425

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference

PubMed ID

25604425