Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. (Q34923990)

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22 February 2020

title

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis (English)

1 reference

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22 February 2020

10

1 reference

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22 February 2020

9

Jeffery W Kelly

1 reference

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22 February 2020

author name string

Joseph C Genereux

1

1 reference

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22 February 2020

Song Qu

2

1 reference

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22 February 2020

Minghai Zhou

3

1 reference

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22 February 2020

Lisa M Ryno

4

1 reference

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22 February 2020

Shiyu Wang

5

1 reference

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22 February 2020

Matthew D Shoulders

6

1 reference

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22 February 2020

Randal J Kaufman

7

1 reference

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22 February 2020

Corinne I Lasmézas

8

1 reference

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22 February 2020

language of work or name

English

0 references

publication date

31 October 2014

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22 February 2020

1 reference

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22 February 2020

volume

34

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22 February 2020

page(s)

4-19

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22 February 2020

issue

1

1 reference

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describes a project that uses

22 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4291477/fullTextXML

inferred from PubMed Central ID database lookup

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8 July 2018

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8 July 2018

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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ERdj3, a luminal ER DnaJ homologue, binds directly to unfolded proteins in the mammalian ER: identification of critical residues

8 July 2018

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8 July 2018

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Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

8 July 2018

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Regulated release of ERdj3 from unfolded proteins by BiP

8 July 2018

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8 July 2018

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The activities and function of molecular chaperones in the endoplasmic reticulum

8 July 2018

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8 July 2018

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8 July 2018

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Insights into prion strains and neurotoxicity

8 July 2018

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Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol.

8 July 2018

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Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell

8 July 2018

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

8 July 2018

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Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides.

8 July 2018

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Extracellular disulfide exchange and the regulation of cellular function

8 July 2018

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8 July 2018

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The biological and chemical basis for tissue-selective amyloid disease

8 July 2018

1 reference

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

8 July 2018

1 reference

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ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

8 July 2018

1 reference

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8 July 2018

The systemic amyloidoses

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

8 July 2018

1 reference

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A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

8 July 2018

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

8 July 2018

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The KDEL receptor modulates the endoplasmic reticulum stress response through mitogen-activated protein kinase signaling cascades

8 July 2018

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D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?

8 July 2018

1 reference

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

8 July 2018

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Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging

8 July 2018

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The action of molecular chaperones in the early secretory pathway

8 July 2018

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An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured

8 July 2018

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Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast

8 July 2018

1 reference

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

8 July 2018

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8 July 2018

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Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

8 July 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

8 July 2018

1 reference

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Alternative conformations of amyloidogenic proteins govern their behavior

8 July 2018

1 reference

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A new variant of Creutzfeldt-Jakob disease in the UK.

8 July 2018

1 reference

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A C-terminal signal prevents secretion of luminal ER proteins

8 July 2018

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The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins

8 July 2018

1 reference

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Perturbation of cellular calcium blocks exit of secretory proteins from the rough endoplasmic reticulum

8 July 2018

1 reference

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Cerebrospinal fluid and plasma clusterin levels in Parkinson's disease

8 July 2018

1 reference

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Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions.

26 October 2018

1 reference

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Total prion protein levels in the cerebrospinal fluid are reduced in patients with various neurological disorders.

26 October 2018

1 reference

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A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Understanding the molecular basis for the inhibition of the Alzheimer's Abeta-peptide oligomerization by human serum albumin using saturation transfer difference and off-resonance relaxation NMR spectroscopy.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Energetic characteristics of the new transthyretin variant A25T may explain its atypical central nervous system pathology.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291477

Endogenous proteins controlling amyloid beta-peptide polymerization. Possible implications for beta-amyloid formation in the central nervous system and in peripheral tissues

26 October 2018

1 reference

12 December 2020

Endoplasmic Reticulum Stress Associated with Extracellular Aggregates

1 reference

12 December 2020

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

12 December 2020

Perturbation of cellular calcium induces secretion of luminal ER proteins

1 reference

12 December 2020

Secretion, surface localization, turnover, and steady state expression of protein disulfide isomerase in rat hepatocytes

1 reference

12 December 2020

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

12 December 2020

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMBJ.201488896

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361606%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361606%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361606%20AND%20SRC:MED&resulttype=core&format=json