Insights into prion strains and neurotoxicity (Q36856446)

16 August 2017

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title

Insights into prion strains and neurotoxicity (English)

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16 August 2017

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2

Mathias Heikenwalder

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Adriano Aguzzi

object named as

Adriano Aguzzi

series ordinal

1

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Magdalini Polymenidou

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3

object named as

Magdalini Polymenidou

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16 August 2017

1 July 2007

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Nature Reviews Molecular Cell Biology

16 August 2017

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16 August 2017

8

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16 August 2017

7

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16 August 2017

552-561

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https://scigraph.springernature.com/pub.10.1038/nrm2204

16 August 2017

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cites work

Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain

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Immunization delays the onset of prion disease in mice.

21 January 2018

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Breaking immune tolerance to the prion protein using prion protein peptides plus oligodeoxynucleotide-CpG in mice.

21 January 2018

1 reference

Human prion diseases: epidemiology and integrated risk assessment

21 January 2018

1 reference

Transmissible spongiform encephalopathies.

31 March 2020

1 reference

Novel proteinaceous infectious particles cause scrapie

31 March 2020

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Self-replication and scrapie

31 March 2020

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Cannibals and garbage piles

31 March 2020

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A cellular gene encodes scrapie PrP 27-30 protein

31 March 2020

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A 'unified theory' of prion propagation

31 March 2020

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Mice devoid of PrP are resistant to scrapie

31 March 2020

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Mammalian prion biology: one century of evolving concepts

31 March 2020

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Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

31 March 2020

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Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis

31 March 2020

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The most infectious prion protein particles.

31 March 2020

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Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

31 March 2020

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Biomedicine. A view from the top--prion diseases from 10,000 feet

31 March 2020

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Identification of a protein that purifies with the scrapie prion.

31 March 2020

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Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

31 March 2020

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Strain fidelity of chronic wasting disease upon murine adaptation

31 March 2020

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Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions

31 March 2020

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Coincident scrapie infection and nephritis lead to urinary prion excretion.

31 March 2020

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PrPSc in mammary glands of sheep affected by scrapie and mastitis

31 March 2020

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Transmission of BSE by blood transfusion in sheep

31 March 2020

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Infectious prions in the saliva and blood of deer with chronic wasting disease

31 March 2020

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Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

31 March 2020

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Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

31 March 2020

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Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report.

31 March 2020

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Prion infections, blood and transfusions

31 March 2020

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Eight prion strains have PrP(Sc) molecules with different conformations

31 March 2020

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Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles

31 March 2020

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Prions as adaptive conduits of memory and inheritance

31 March 2020

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Prions of yeast as epigenetic phenomena: high protein "copy number" inducing protein "silencing".

31 March 2020

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Understanding the diversity of prions.

31 March 2020

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Scrapie produced experimentally in goats with special reference to the clinical syndrome

31 March 2020

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Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation.

31 March 2020

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Biological evidence that scrapie agent has an independent genome.

31 March 2020

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Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters

31 March 2020

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Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages

31 March 2020

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Subclinical prion infection in humans and animals

31 March 2020

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Species-barrier-independent prion replication in apparently resistant species

31 March 2020

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Unaltered susceptibility to BSE in transgenic mice expressing human prion protein.

31 March 2020

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Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

31 March 2020

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Transmission barriers for bovine, ovine, and human prions in transgenic mice

31 March 2020

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Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

31 March 2020

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Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp.

31 March 2020

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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

31 March 2020

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Molecular neurology of prion disease

31 March 2020

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PrP glycoforms are associated in a strain-specific ratio in native PrPSc

31 March 2020

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Selective neuronal targeting in prion disease

31 March 2020

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Glycosylation deficiency at either one of the two glycan attachment sites of cellular prion protein preserves susceptibility to bovine spongiform encephalopathy and scrapie infections.

31 March 2020

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Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties.

31 March 2020

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Non-genetic propagation of strain-specific properties of scrapie prion protein.

31 March 2020

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Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

31 March 2020

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Genetic influence on the structural variations of the abnormal prion protein

31 March 2020

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Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes.

31 March 2020

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Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

31 March 2020

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Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

31 March 2020

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Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

31 March 2020

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Multiple prion types in the same brain: is a molecular diagnosis of CJD possible?

31 March 2020

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Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease.

31 March 2020

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Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

31 March 2020

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Reciprocal interference between specific CJD and scrapie agents in neural cell cultures

31 March 2020

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Prion interference is due to a reduction in strain-specific PrPSc levels

31 March 2020

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Vaccination with an attenuated Creutzfeldt-Jakob disease strain prevents expression of a virulent agent

31 March 2020

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Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease

31 March 2020

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Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy

31 March 2020

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Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

31 March 2020

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Games played by rogue proteins in prion disorders and Alzheimer's disease

31 March 2020

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Cell biology: Infectious Alzheimer's disease?

31 March 2020

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Antiprion immunotherapy: to suppress or to stimulate?

31 March 2020

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Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease.

31 March 2020

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Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease.

31 March 2020

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Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease

31 March 2020

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PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain.

31 March 2020

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Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

31 March 2020

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Extraneural prion neuroinvasion without lymphoreticular system infection

31 March 2020

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Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

31 March 2020

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

31 March 2020

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Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

31 March 2020

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Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease.

31 March 2020

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Normal host prion protein necessary for scrapie-induced neurotoxicity.

31 March 2020

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Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

31 March 2020

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Anchorless prion protein results in infectious amyloid disease without clinical scrapie

31 March 2020

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Cell biology. Prion toxicity: all sail and no anchor.

31 March 2020

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Alternative roles for CD59.

31 March 2020

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Prion-induced amyloid heart disease with high blood infectivity in transgenic mice

31 March 2020

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

31 March 2020

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Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC

31 March 2020

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Lethal recessive myelin toxicity of prion protein lacking its central domain

31 March 2020

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A transmembrane form of the prion protein in neurodegenerative disease

31 March 2020

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Transmissible and genetic prion diseases share a common pathway of neurodegeneration

31 March 2020

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Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.

31 March 2020

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Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

31 March 2020

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Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

31 March 2020

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Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

31 March 2020

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Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons

31 March 2020

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GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice.

31 March 2020

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Visualization of prion infection in transgenic mice expressing green fluorescent protein-tagged prion protein.

31 March 2020

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Selective expression of prion protein in peripheral tissues of the adult mouse.

31 March 2020

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Evidence of presynaptic location and function of the prion protein

31 March 2020

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Developmental expression of the prion protein gene in glial cells.

31 March 2020

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Scrapie prion protein contains a phosphatidylinositol glycolipid

31 March 2020

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Asparagine-linked glycosylation of the scrapie and cellular prion proteins

31 March 2020

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NMR structure of the mouse prion protein domain PrP(121-231)

31 March 2020

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Three-dimensional structures of prion proteins

31 March 2020

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Crystal structure of the human prion protein reveals a mechanism for oligomerization

31 March 2020

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Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

31 March 2020

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The cellular prion protein binds copper in vivo

31 March 2020

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Copper binding to the octarepeats of the prion protein. Affinity, specificity, folding, and cooperativity: insights from circular dichroism

31 March 2020

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Probing copper2+ binding to the prion protein using diamagnetic nickel2+ and 1H NMR: the unstructured N terminus facilitates the coordination of six copper2+ ions at physiological concentrations

31 March 2020

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Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity.

31 March 2020

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Brain copper content and cuproenzyme activity do not vary with prion protein expression level

31 March 2020

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No superoxide dismutase activity of cellular prion protein in vivo.

31 March 2020

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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

31 March 2020

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Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

31 March 2020

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Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

31 March 2020

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Monoclonal antibodies inhibit prion replication and delay the development of prion disease

31 March 2020

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Induction of antibodies against murine full-length prion protein in wild-type mice

31 March 2020

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Anti-prion antibodies for prophylaxis following prion exposure in mice

31 March 2020

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Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice.

31 March 2020

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Self prion protein peptides are immunogenic in Lewis rats

31 March 2020

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Modulation of proteinase-K resistant prion protein by prion peptide immunization.

31 March 2020

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Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent

31 March 2020

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Generation of antibodies against prion protein in wild-type mice via helix 1 peptide immunization

31 March 2020

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Identification of two immunogenic domains of the prion protein--PrP--which activate class II-restricted T cells and elicit antibody responses against the native molecule.

31 March 2020

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Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.

31 March 2020

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Virus-like particles as a modular system for novel vaccines

31 March 2020

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Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.

31 March 2020

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Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

31 March 2020

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Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

31 March 2020

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Competition between Different Scrapie Agents in Mice

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRM2204

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release_hl7fgvad2bdlldbetvty5bvrxe

16 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/hl7fgvad2bdlldbetvty5bvrxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

17585315

1 reference

PubMed ID

17585315