IL-1β and IL-18: inflammatory markers or mediators of hypertension? (Q34914125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

8 April 2021

IL-1β and IL-18: inflammatory markers or mediators of hypertension? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

main subject

arterial hypertension

3 references

13 March 2019

17 June 2019

20 November 2019

1 reference

20 November 2019

inflammation mediators

1 reference

8 April 2021

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Grant R. Drummond

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2

C G Sobey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

S M Krishnan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

E Latz

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

1 December 2014

5 references

13 March 2019

17 June 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

8 April 2021

British Journal of Pharmacology

5 references

13 March 2019

17 June 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

8 April 2021

171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

5589-5602

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

12 March 2020

copyright license

4 references

13 March 2019

17 June 2019

20 November 2019

on focus list of Wikimedia project

8 April 2021

ScienceSource

0 references

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Canakinumab in patients with cryopyrin-associated periodic syndrome: an update for clinicians

8 July 2018

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ST2 as a cardiovascular risk biomarker: from the bench to the bedside

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Oxidative stress in hypertension: role of the kidney

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The role of inflammasome-derived IL-1 in driving IL-17 responses

8 July 2018

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ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

8 July 2018

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P2X7 receptors: channels, pores and more

8 July 2018

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Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.

8 July 2018

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A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

8 July 2018

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Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage

8 July 2018

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NLRP3 inflammasomes link inflammation and metabolic disease

8 July 2018

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Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

8 July 2018

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Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

8 July 2018

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The IL-33/ST2 pathway--A new therapeutic target in cardiovascular disease

8 July 2018

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Renal inflammation, autoimmunity and salt-sensitive hypertension

8 July 2018

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Reactive oxygen species and vascular biology: implications in human hypertension

8 July 2018

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The potential for caspases in drug discovery

8 July 2018

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Ac-YVAD-CMK Decreases Blood-Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model

8 July 2018

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

8 July 2018

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8 July 2018

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NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

8 July 2018

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Progression of cardiovascular damage: the role of renin-angiotensin system blockade

8 July 2018

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8 July 2018

NLRP3 has a sweet tooth

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The NLRP3 inflammasome: a sensor for metabolic danger?

8 July 2018

1 reference

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Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction

8 July 2018

1 reference

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

8 July 2018

1 reference

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Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases

8 July 2018

1 reference

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Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

8 July 2018

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Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

8 July 2018

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Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice.

8 July 2018

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Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

8 July 2018

1 reference

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

8 July 2018

1 reference

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Anakinra for rheumatoid arthritis: a systematic review

8 July 2018

1 reference

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Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding

8 July 2018

1 reference

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NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury

8 July 2018

1 reference

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The role of interleukin 18 in the pathogenesis of hypertension-induced vascular disease

8 July 2018

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Extracellular ATP in the immune system: more than just a "danger signal".

8 July 2018

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Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial

8 July 2018

1 reference

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IL-1, IL-18, and IL-33 families of cytokines

8 July 2018

1 reference

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

8 July 2018

1 reference

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

8 July 2018

1 reference

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Selective P2X(7) receptor antagonists for chronic inflammation and pain

8 July 2018

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

8 July 2018

1 reference

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The inflammasome: a danger sensing complex triggering innate immunity

8 July 2018

1 reference

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Intracellular NOD-like receptors in host defense and disease

8 July 2018

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Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction

8 July 2018

1 reference

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Interleukin 1-beta (IL-1beta) enhances contractile responses in endothelium-denuded aorta from hypertensive, but not normotensive, rats

8 July 2018

1 reference

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Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states

8 July 2018

1 reference

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Inflammatory caspases: targets for novel therapies

8 July 2018

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ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

8 July 2018

1 reference

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Inflammatory caspases and inflammasomes: master switches of inflammation

8 July 2018

1 reference

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Is hypertension an inflammatory process?

8 July 2018

1 reference

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Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

8 July 2018

1 reference

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Cryopyrin activates the inflammasome in response to toxins and ATP

8 July 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

8 July 2018

1 reference

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Increased superoxide anion production by interleukin-1beta impairs nitric oxide-mediated relaxation in resistance arteries

8 July 2018

1 reference

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Interleukin 18 (IL-18) upregulation in acute rejection of kidney allograft.

8 July 2018

1 reference

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Associations of serum IL-18 levels with carotid intima-media thickness

8 July 2018

1 reference

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Reactive oxygen species in vascular biology: implications in hypertension

8 July 2018

1 reference

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Hypertensive response to acute stress is attenuated in interleukin-6 knockout mice

8 July 2018

1 reference

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Anakinra: an inhibitor of IL-1 for the treatment of rheumatoid arthritis

8 July 2018

1 reference

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Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release

8 July 2018

1 reference

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Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

8 July 2018

1 reference

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Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all.

8 July 2018

1 reference

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The IL-1 family and inflammatory diseases.

8 July 2018

1 reference

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Can angiotensin II type 2 receptors have deleterious effects in cardiovascular disease? Implications for therapeutic blockade of the renin-angiotensin system

8 July 2018

1 reference

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Inflammation in pulmonary arterial hypertension.

8 July 2018

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Inflammation, endothelial dysfunction, and the risk of high blood pressure: epidemiologic and biological evidence

8 July 2018

1 reference

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Inflammation and angiotensin II.

8 July 2018

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Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells

8 July 2018

1 reference

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Pattern recognition receptors: doubling up for the innate immune response

8 July 2018

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Early statin therapy restores endothelial function in children with familial hypercholesterolemia

8 July 2018

1 reference

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Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

IL-1 and IL-18 receptors, and their extended family.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Sympathetic overactivity in hypertension: a risk factor for cardiovascular disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

The renin-angiotensin-aldosterone system: a specific target for hypertension management

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Suicidal tendencies: apoptotic cell death by caspase family proteinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Atherosclerosis — An Inflammatory Disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Binding of interleukin-18 to the interleukin-1 receptor homologous receptor IL-1Rrp1 leads to activation of signaling pathways similar to those used by interleukin-1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Interleukin-1 receptor antagonist: role in biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Biologic basis for interleukin-1 in disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Evidence of N-methyl-D-aspartate receptor-mediated modulation of the aortic baroreceptor reflex in the rat nucleus tractus solitarii.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Ageing alters the production of nitric oxide and prostanoids after IL-1beta exposure in mesenteric resistance arteries.

8 July 2018

1 reference

Interleukin (IL) 1beta induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT/IkappaB kinase alpha pathway targeting activator protein-1.

21 January 2018

1 reference

Increased serum levels of interleukin-1beta in the systemic circulation of patients with essential hypertension: additional risk factor for atherogenesis in hypertensive patients?

21 January 2018

1 reference

Preactivated peripheral blood monocytes in patients with essential hypertension.

21 January 2018

1 reference

Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis

21 January 2018

1 reference

Renal NF-kappaB activation and TNF-alpha upregulation correlate with salt-sensitive hypertension in Dahl salt-sensitive rats.

21 January 2018

1 reference

Leukocyte infiltration and ICAM-1 expression in two-kidney one-clip hypertension

21 January 2018

1 reference

P2X(7) receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats.

21 January 2018

1 reference

Neuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats

21 January 2018

1 reference

Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans

21 January 2018

1 reference

Valsartan reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension

21 January 2018

1 reference

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

21 January 2018

1 reference

Interleukin-1 beta rapidly inhibits aortic endothelium-dependent relaxation by a DNA transcription-dependent mechanism.

21 January 2018

1 reference

Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism

21 January 2018

1 reference

Upregulated IL-18 expression in type 2 diabetic subjects with nephropathy: TGF-beta1 enhanced IL-18 expression in human renal proximal tubular epithelial cells.

21 January 2018

1 reference

Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients.

21 January 2018

1 reference

Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial

21 January 2018

1 reference

Imbalance of T-cell subsets in angiotensin II-infused hypertensive rats with kidney injury

21 January 2018

1 reference

Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats

21 January 2018

1 reference

Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days

21 January 2018

1 reference

What does intima???media thickness tell us?

21 January 2018

1 reference

Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models

21 January 2018

1 reference

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

21 January 2018

1 reference

Vascular inflammation, insulin resistance, and endothelial dysfunction in salt-sensitive hypertension: role of nuclear factor kappa B activation.

21 January 2018

1 reference

On Uric Acid and Arterial Tension.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Use of statins and blood pressure control in treated hypertensive patients with hypercholesterolemia

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290704

Do Statins Reduce Blood Pressure?

26 October 2018

1 reference

Inflammation and hypertension: the search for a link

21 January 2018

1 reference

12 December 2020

Monocrotaline-induced pulmonary arterial hypertension is attenuated by TNF-α antagonists via the suppression of TNF-α expression and NF-κB pathway in rats

1 reference

12 December 2020

Antihypertensive effects of statins: a meta-analysis of prospective controlled studies

1 reference

12 December 2020

P2X7 deficiency attenuates hypertension and renal injury in deoxycorticosterone acetate-salt hypertension

1 reference

12 December 2020

Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice

1 reference

12 December 2020

Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis

1 reference

12 December 2020

Angiotensin II hypertension is attenuated in interleukin-6 knockout mice

1 reference

12 December 2020

Plasma concentrations of adhesion molecules and chemokines in patients with essential hypertension

1 reference

12 December 2020

Hypoxia/reoxygenation stimulates endothelial cells to promote interleukin-1 and interleukin-6 production. Effects of free radical scavengers

1 reference

12 December 2020

Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits

1 reference

12 December 2020

Renal injury from angiotensin II-mediated hypertension

1 reference

12 December 2020

Pro-inflammatory cytokines in patients with essential hypertension

1 reference

12 December 2020

NOX-free inflammasome activation

1 reference

12 December 2020

Induction of ICE and inhibition of c-fos, jun D and zif 268 in 12-month old spontaneously hypertensive rats

1 reference

12 December 2020

Circulating adhesion molecules levels in type 2 diabetes mellitus and hypertension

1 reference

12 December 2020

An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension

1 reference

12 December 2020

NF-kappaB inhibition ameliorates angiotensin II-induced inflammatory damage in rats

1 reference

12 December 2020

Uric acid as an independent risk factor in the treatment of hypertension

1 reference

12 December 2020

Superoxide dismutase 1 regulates caspase-1 and endotoxic shock

1 reference

12 December 2020

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension

1 reference

12 December 2020

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

1 reference

12 December 2020

ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs

1 reference

12 December 2020

Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines

1 reference

12 December 2020

Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin

1 reference

12 December 2020

Identifiers

DOI

10.1111/BPH.12876

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25117218%20AND%20SRC:MED&resulttype=core&format=json