Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs (Q34830422)

4 August 2017

Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs (English)

1 reference

4 August 2017

L A Aagaard

1

1 reference

4 August 2017

J Zhang

2

1 reference

4 August 2017

K J von Eije

3

1 reference

4 August 2017

H Li

4

1 reference

4 August 2017

P Saetrom

5

1 reference

4 August 2017

M Amarzguioui

6

1 reference

4 August 2017

J J Rossi

7

1 reference

4 August 2017

18 September 2008

1 reference

4 August 2017

1 reference

4 August 2017

15

1 reference

4 August 2017

1536-1549

1 reference

4 August 2017

23

1 reference

https://scigraph.springernature.com/pub.10.1038/gt.2008.147

4 August 2017

0 references

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Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition

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Human immunodeficiency virus type 1 escape is restricted when conserved genome sequences are targeted by RNA interference

8 July 2018

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Combinatorial RNAi: a winning strategy for the race against evolving targets?

8 July 2018

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A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha

8 July 2018

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Strategies for silencing human disease using RNA interference

8 July 2018

1 reference

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Processing of intronic microRNAs

8 July 2018

1 reference

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Silencing of HIV-1 with RNA interference: a multiple shRNA approach

8 July 2018

1 reference

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Lessons from Nature: microRNA-based shRNA libraries

8 July 2018

1 reference

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Expressing short hairpin RNAs in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Simultaneous targeting of HCV replication and viral binding with a single lentiviral vector containing multiple RNA interference expression cassettes.

8 July 2018

1 reference

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Silencing Viral Infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

8 July 2018

1 reference

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Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.

8 July 2018

1 reference

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

8 July 2018

1 reference

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Second-generation shRNA libraries covering the mouse and human genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Suppression of RNA interference by adenovirus virus-associated RNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A microRNA polycistron as a potential human oncogene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Clustering and conservation patterns of human microRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Hepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding Region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

MicroRNA biogenesis: coordinated cropping and dicing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Small RNAs: classification, biogenesis, and function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

The Drosha-DGCR8 complex in primary microRNA processing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A protein sensor for siRNA asymmetry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Processing of primary microRNAs by the Microprocessor complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

The Microprocessor complex mediates the genesis of microRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

MicroRNA genes are transcribed by RNA polymerase II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Unlocking the potential of the human genome with RNA interference

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Identification of mammalian microRNA host genes and transcription units

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Molecular evolution of a microRNA cluster

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

MicroRNAs: genomics, biogenesis, mechanism, and function

8 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

8 July 2018

https://api.crossref.org/works/10.1038%2FGT.2008.147

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Nuclear export of microRNA precursors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Functional siRNAs and miRNAs Exhibit Strand Bias

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Asymmetry in the assembly of the RNAi enzyme complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Human immunodeficiency virus type 1 escape from RNA interference

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

The nuclear RNase III Drosha initiates microRNA processing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A nucleolar TAR decoy inhibitor of HIV-1 replication.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

MicroRNA maturation: stepwise processing and subcellular localization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Short interfering RNA confers intracellular antiviral immunity in human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

A system for stable expression of short interfering RNAs in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Position within the host intron is critical for efficient processing of box C/D snoRNAs in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155610

Regulation of apoptosis by alternative pre-mRNA splicing

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.147

Design of expression vectors for RNA interference based on miRNAs and RNA splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.147

Reliable prediction of Drosha processing sites improves microRNA gene prediction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.147

Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.147

Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.147

Splicing-dependent and -independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18800151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18800151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/GT.2008.147

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference