E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8 (Q34828705)

4 August 2017

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8 (English)

1 reference

E2F transcription factor 1 Dmel_CG6376

4 August 2017

1 reference

Cyclin-dependent kinase 8 Dmel_CG10572

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Erick J Morris

1

1 reference

4 August 2017

Jun-Yuan Ji

2

1 reference

4 August 2017

Fajun Yang

3

1 reference

4 August 2017

Luisa Di Stefano

4

1 reference

4 August 2017

Anabel Herr

5

1 reference

4 August 2017

Nam-Sung Moon

6

1 reference

4 August 2017

Eun-Jeong Kwon

7

1 reference

4 August 2017

Kevin M Haigis

8

1 reference

4 August 2017

Anders M Näär

9

1 reference

4 August 2017

Nicholas J Dyson

10

1 reference

4 August 2017

language of work or name

English

0 references

publication date

14 September 2008

1 reference

4 August 2017

1 reference

4 August 2017

455

1 reference

4 August 2017

552-556

1 reference

4 August 2017

7212

1 reference

https://scigraph.springernature.com/pub.10.1038/nature07310

4 August 2017

0 references

cites work

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

An E2F1-dependent gene expression program that determines the balance between proliferation and cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Myc deletion rescues Apc deficiency in the small intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Wnt/beta-catenin signaling in development and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

The retinoblastoma protein is required for Ras-induced oncogenic transformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Distinctions in the specificity of E2F function revealed by gene expression signatures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

c-Myc-regulated microRNAs modulate E2F1 expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

A microRNA polycistron as a potential human oncogene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Dynamic regulation of pol II transcription by the mammalian Mediator complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

E2F1 up-regulates the expression of the tumour suppressor axin2 both by activation of transcription and by mRNA stabilisation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Identification of Tcf-4 as a transcriptional target of p53 signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Specificity in the activation and control of transcription factor E2F-dependent apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Down-regulation of beta-catenin by activated p53.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

p73beta, a variant of p73, enhances Wnt/beta-catenin signaling in Saos-2 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Lessons from hereditary colorectal cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Mediator is a transducer of Wnt/beta-catenin signaling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Making a better RNAi vector for Drosophila: use of intron spacers

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148807

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18794899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased expression of the retinoblastoma gene in human colorectal carcinomas relative to normal colonic mucosa

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18794899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE07310

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference