E2F1 up-regulates the expression of the tumour suppressor axin2 both by activation of transcription and by mRNA stabilisation (Q24298031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

E2F1 up-regulates the expression of the tumour suppressor axin2 both by activation of transcription and by mRNA stabilisation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

E2F transcription factor 1

9 January 2020

main subject

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GOA release 2020-03-11

mRNA stabilization

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GOA release 2020-03-11

author

Thomas A Hughes

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Hugh Brady

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Hugh J M Brady

series ordinal

2

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language of work or name

English

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publication date

1 April 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

Biochemical and Biophysical Research Communications

9 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

329

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

1267-1274

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9 January 2020

issue

4

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mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure.

9 January 2020

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Cross-talk between pRb/E2F and Wnt/beta-catenin pathways: E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

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Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

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The retinoblastoma tumour suppressor in development and cancer

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Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

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7 January 2021

Identification of a target RNA motif for RNA-binding protein HuR.

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The identification of E2F1-specific target genes

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Regulation of the cyclin E gene by transcription factor E2F1

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Distinct roles for E2F proteins in cell growth control and apoptosis

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Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

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A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR.

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7 January 2021

A 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinase

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7 January 2021

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Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal

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7 January 2021

Expression of axin2 is regulated by the alternative 5'-untranslated regions of its mRNA

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7 January 2021

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7 January 2021

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7 January 2021

Gene expression changes in response to E2F1 activation.

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7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

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7 January 2021

Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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E2F and Ras Synergize in Transcriptionally Activating p14ARFExpression

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15766563%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference