Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells (Q34805329)

4 August 2017

Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells (English)

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4 August 2017

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Bui Thi Kim Ly

1

1 reference

4 August 2017

Hoang Thanh Chi

2

1 reference

4 August 2017

Makoto Yamagishi

3

1 reference

4 August 2017

Yasuhiko Kano

4

1 reference

4 August 2017

Yukihiko Hara

5

1 reference

4 August 2017

Kazumi Nakano

6

1 reference

4 August 2017

Yuko Sato

7

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4 August 2017

Toshiki Watanabe

8

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4 August 2017

language of work or name

English

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publication date

20 June 2013

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4 August 2017

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4 August 2017

8

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4 August 2017

6

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4 August 2017

e66378

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Creative Commons Attribution 4.0 International

4 August 2017

start time

20 June 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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FLT3 as a therapeutic target in AML: still challenging after all these years

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Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions

8 July 2018

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Green tea (-)-epigalocatechin-3-gallate inhibits KIT activity and causes caspase-dependent cell death in gastrointestinal stromal tumor including imatinib-resistant cells

8 July 2018

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(-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2.

8 July 2018

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(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor

8 July 2018

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Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor

8 July 2018

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Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.

8 July 2018

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EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells

8 July 2018

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Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

8 July 2018

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Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML.

8 July 2018

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A proteomic snapshot of the human heat shock protein 90 interactome

8 July 2018

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Heat shock response modulators as therapeutic tools for diseases of protein conformation

8 July 2018

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Constantly updated knowledge of Hsp90.

8 July 2018

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AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

8 July 2018

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Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival

8 July 2018

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Altered Hsp90 function in cancer: a unique therapeutic opportunity.

8 July 2018

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Therapeutic and diagnostic implications of Hsp90 activation

8 July 2018

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FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

8 July 2018

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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

8 July 2018

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Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells.

8 July 2018

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

8 July 2018

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The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

8 July 2018

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Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).

8 July 2018

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Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts.

8 July 2018

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In vitro schedule-dependent interaction between paclitaxel and SN-38 (the active metabolite of irinotecan) in human carcinoma cell lines

8 July 2018

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Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells

8 July 2018

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Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23).

8 July 2018

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Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

8 July 2018

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Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells

8 July 2018

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Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3688791

Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)

8 July 2018

1 reference

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Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines

8 July 2018

1 reference

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Effects of vincristine in combination with methotrexate and other antitumor agents in human acute lymphoblastic leukemia cells in culture.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3688791

The role of heat-shock proteins as molecular chaperones

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3688791

Phenotypic and genotypic characterization of 14 leukemia and lymphoma cell lines with 11q23 translocations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3688791

Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia

8 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

Microarray-assisted pathway analysis identifies mitogen-activated protein kinase signaling as a mediator of resistance to the green tea polyphenol epigallocatechin 3-gallate in her-2/neu-overexpressing breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066378

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

21 January 2018

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Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.

21 January 2018

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Kinetics of bone marrow cell production in human acute and chronic myeloid leukemias

26 October 2018

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12 December 2020

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia

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12 December 2020

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia

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12 December 2020

Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation

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12 December 2020

10.1371/JOURNAL.PONE.0066378

Identifiers

DOI

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4 August 2017

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4 August 2017

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