Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction (Q34792629)

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English	Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction (English)

1 reference

Europe PubMed Central

4 August 2017

1 reference

based on heuristic

inferred from title

author name string

Hui-Ren Zhou

1

1 reference

Europe PubMed Central

4 August 2017

Kaiyu He

2

1 reference

Europe PubMed Central

4 August 2017

Jeff Landgraf

3

1 reference

Europe PubMed Central

4 August 2017

Xiao Pan

4

1 reference

Europe PubMed Central

4 August 2017

James J Pestka

5

1 reference

Europe PubMed Central

4 August 2017

publication date

16 December 2014

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

6

1 reference

Europe PubMed Central

4 August 2017

12

1 reference

Europe PubMed Central

4 August 2017

3406-3425

1 reference

Europe PubMed Central

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

16 December 2014

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April 2022 Public Data File from Crossref

copyright status

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Dynamic changes in ribosome-associated proteome and phosphoproteome during deoxynivalenol-induced translation inhibition and ribotoxic stress

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PKR-dependent inflammatory signals

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Analysis of high-affinity binding of protein kinase R to double-stranded RNA

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Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage

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8 July 2018

Translation inhibitors and their unique biological properties

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The structure of the eukaryotic ribosome at 3.0 Å resolution

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Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes

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Satratoxin G interaction with 40S and 60S ribosomal subunits precedes apoptosis in the macrophage

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Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280541

8 July 2018

Satratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independent

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8 July 2018

Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage

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8 July 2018

Structure and function of the protein kinase R.

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8 July 2018

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Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

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Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox

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8 July 2018

Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response

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8 July 2018

The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity

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Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR

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8 July 2018

Signal integration via PKR.

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8 July 2018

Nucleotides of 18S rRNA surrounding mRNA codons at the human ribosomal A, P, and E sites: a crosslinking study with mRNA analogs carrying an aryl azide group at either the uracil or the guanine residue

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8 July 2018

Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.

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8 July 2018

JNK2 and IKKbeta are required for activating the innate response to viral infection

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8 July 2018

PKR; a sentinel kinase for cellular stress

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Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR).

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8 July 2018

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

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8 July 2018

How to measure and predict the molar absorption coefficient of a protein

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Tumor-suppressor genes: news about the interferon connection

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The effect of pentachlorophenol and its metabolite tetrachlorohydroquinone on RNA, protein, and ribosome synthesis in Saccharomyces cells.

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Inhibition of Protein Synthesis in Intact HeLa Cells

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Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells

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Secondary structure of heterogeneous nuclear RNA: Two classes of double-stranded RNA in native ribonucleoprotein

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Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products

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PKR and the ribosome compete for mRNA.

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Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells.

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RNA under attack: cellular handling of RNA damage

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Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2

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https://pubmed.ncbi.nlm.nih.gov/25521494

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Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation

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https://pubmed.ncbi.nlm.nih.gov/25521494

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Identifiers

10.3390/TOXINS6123406

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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