The gut microbiome in intestinal fibrosis: environmental protector or provocateur? (Q34778411)

4 August 2017

The gut microbiome in intestinal fibrosis: environmental protector or provocateur? (English)

1 reference

4 August 2017

0 references

Florian Rieder

1

1 reference

PubMed ID

23785034

4 August 2017

language of work or name

English

0 references

publication date

1 June 2013

1 reference

Science Translational Medicine

4 August 2017

1 reference

4 August 2017

5

1 reference

4 August 2017

190

1 reference

4 August 2017

190ps10

1 reference

Therapy for fibrotic diseases: nearing the starting line

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Animal models of intestinal fibrosis: new tools for the understanding of pathogenesis and therapy of human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Inflammation-induced endothelial-to-mesenchymal transition: a novel mechanism of intestinal fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

The aryl hydrocarbon receptor ligand ITE inhibits TGFβ1-induced human myofibroblast differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

The prognostic power of the NOD2 genotype for complicated Crohn's disease: a meta-analysis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Predictors of fibrostenotic Crohn's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Bacterial lipopolysaccharide promotes profibrotic activation of intestinal fibroblasts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Pattern recognition receptors and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Intestinal fibrosis in IBD--a dynamic, multifactorial process

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Cytokines mediating the induction of chronic colitis and colitis-associated fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Toll-like receptors and adaptor molecules in liver disease: update

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

The role of matrix stiffness in regulating cell behavior

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Analysis of bacterial bowel communities of IBD patients: what has it revealed?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

TLR4 enhances TGF-beta signaling and hepatic fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

New insights into nephrogenic systemic fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Wound healing and fibrosis in intestinal disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Toll-like receptor signaling stimulates cell cycle entry and progression in fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Functional role of AhR in the expression of toxic effects by TCDD

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

The role of chemokines and chemokine receptors in mucosal inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Modulation of leukocyte behavior by an inflamed extracellular matrix

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Fibrogenesis. IV. Fibrosis and inflammatory bowel disease: cellular mediators and animal models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Long-term follow-up of patients with Crohn's disease. Relationship between the clinical pattern and prognosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823049

Impact of azathioprine and tumour necrosis factor antagonists on the need for surgery in newly diagnosed Crohn's disease.

7 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Discovering environmental causes of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Activation of COL1A2 promoter in human fibroblasts by Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Prognostic value of plasma endotoxin levels in patients with cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Stimulation of transforming growth factor β1 by enteric bacteria in the pathogenesis of rat intestinal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: results from the CHARM study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Emergence of fibrocytes showing morphological changes in the inflamed colonic mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Altered response of intestinal mucosal fibroblasts to profibrogenic cytokines in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Inflammation location, but not type, determines the increase in TGF-beta1 and IGF-1 expression and collagen deposition in IBD intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Platelet-derived growth factor and its receptors are expressed in areas of both active inflammation and active fibrosis in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Increased expression of epidermal growth factor-receptor in an experimental model of colitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004731

Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease

21 January 2018

1 reference

12 December 2020

Functional TLRs and NODs in human gingival fibroblasts

1 reference

12 December 2020

Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease

1 reference

12 December 2020

Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation

1 reference

12 December 2020

Intestinal myofibroblasts in innate immune responses of the intestine

1 reference

12 December 2020

Hepatic fibrosis and cytochrome P450: experimental models of fibrosis compared to AHR knockout mice

1 reference

12 December 2020

Distinct inflammatory mechanisms mediate early versus late colitis in mice

1 reference

12 December 2020

The insulin-like growth factor (IGF)-system in active ulcerative colitis and Crohn’s disease: Relations to disease activity and corticosteroid treatment

1 reference

12 December 2020

Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?

1 reference

12 December 2020

10.1126/SCITRANSLMED.3004731

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference

PubMed ID

23785034