The promyelocytic leukemia nuclear body: sites of activity? (Q34746892)

4 August 2017

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title

The promyelocytic leukemia nuclear body: sites of activity? (English)

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4 August 2017

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Christopher H Eskiw

1

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PubMed ID

12123283

4 August 2017

David P Bazett-Jones

series ordinal

2

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4 August 2017

1 January 2002

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Biochemistry and Cell Biology

4 August 2017

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4 August 2017

80

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4 August 2017

301-310

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4 August 2017

3

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Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodies

4 August 2017

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Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection

21 January 2018

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Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

21 January 2018

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Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia

21 January 2018

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Fluorescence in situ hybridization: a highly efficient technique of molecular diagnosis and predication for disease course in patients with myeloid leukemias

21 January 2018

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Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).

21 January 2018

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Hepatitis delta virus replication generates complexes of large hepatitis delta antigen and antigenomic RNA that affiliate with and alter nuclear domain 10

21 January 2018

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Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA

21 January 2018

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The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body

21 January 2018

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In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML

21 January 2018

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Nuclear bodies (NBs): a newly "rediscovered" organelle

21 January 2018

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Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.

21 January 2018

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The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner

21 January 2018

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Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

21 January 2018

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Role of CBP/P300 in nuclear receptor signalling

21 January 2018

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Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones

21 January 2018

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Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF

21 January 2018

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Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virus

21 January 2018

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

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The promyelocytic (PML) nuclear compartment and transcription control

21 January 2018

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Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling

21 January 2018

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The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

21 January 2018

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Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells

21 January 2018

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Identification of PML oncogenic domains (PODs) in human megakaryocytes

21 January 2018

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

21 January 2018

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Interferon-induced antiviral Mx1 GTPase is associated with components of the SUMO-1 system and promyelocytic leukemia protein nuclear bodies

21 January 2018

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ICP0 induces the accumulation of colocalizing conjugated ubiquitin

21 January 2018

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Regulation of p53 activity in nuclear bodies by a specific PML isoform

21 January 2018

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In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies

21 January 2018

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The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

21 January 2018

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The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility

21 January 2018

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Direct visualization of a protein nuclear architecture

21 January 2018

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Induction of the pro-myelocytic leukaemia gene by type I and type II interferons

21 January 2018

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Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b

21 January 2018

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

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The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition

21 January 2018

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Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment

21 January 2018

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PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

21 January 2018

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PML protein isoforms and the RBCC/TRIM motif

21 January 2018

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Role of the heat shock response and molecular chaperones in oncogenesis and cell death

21 January 2018

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

21 January 2018

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Human-herpesvirus-8-encoded K8 protein colocalizes with the promyelocytic leukemia protein (PML) bodies and recruits p53 to the PML bodies

21 January 2018

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Disruption of PML-associated nuclear bodies during human cytomegalovirus infection

21 January 2018

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The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.

21 January 2018

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Role of PML and PML-RARalpha in Mad-mediated transcriptional repression

21 January 2018

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Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter

21 January 2018

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The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1

21 January 2018

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Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments

21 January 2018

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Functional analysis and intracellular localization of p53 modified by SUMO-1.

21 January 2018

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The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.

21 January 2018

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An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

21 January 2018

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

21 January 2018

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Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

21 January 2018

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Regulation of Pax3 transcriptional activity by SUMO-1-modified PML

21 January 2018

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The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

21 January 2018

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The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0.

21 January 2018

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Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).

21 January 2018

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Nuclear domain 10 (ND10) associated proteins are also present in nuclear bodies and redistribute to hundreds of nuclear sites after stress

21 January 2018

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Review: properties and assembly mechanisms of ND10, PML bodies, or PODs

21 January 2018

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Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?

21 January 2018

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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

21 January 2018

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Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

21 January 2018

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Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot

21 January 2018

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Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins

21 January 2018

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PML interaction with p53 and its role in apoptosis and replicative senescence

21 January 2018

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Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

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PML induces a novel caspase-independent death process

21 January 2018

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Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways

21 January 2018

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Role and fate of PML nuclear bodies in response to interferon and viral infections

21 January 2018

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PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator

21 January 2018

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Macromolecular domains within the cell nucleus

21 January 2018

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Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1

21 January 2018

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Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin- associated nuclear bodies

21 January 2018

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Adenovirus early E4 genes in viral oncogenesis

21 January 2018

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The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control

21 January 2018

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Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication

21 January 2018

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Interferon-beta induces S phase slowing via up-regulated expression of PML in squamous carcinoma cells

21 January 2018

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Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO.

21 January 2018

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Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product

21 January 2018

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Origin-independent assembly of Kaposi's sarcoma-associated herpesvirus DNA replication compartments in transient cotransfection assays and association with the ORF-K8 protein and cellular PML.

21 January 2018

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The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

21 January 2018

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The transcriptional role of PML and the nuclear body

21 January 2018

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Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O02-079

1 reference

4 August 2017

1 reference

PubMed ID

12123283