PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1 (Q24670576)

2

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D Negorev

3

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O V Vladimirova

4

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N Neff

5

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T Kamitani

6

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E T Yeh

7

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J F Strauss

8

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G G Maul

Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development

9

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language of work or name

English

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publication date

18 October 1999

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published in

Journal of Cell Biology

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volume

147

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page(s)

221-34

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issue

2

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cites work

1 reference

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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

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Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1

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The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

7 April 2017

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Daxx, a novel Fas-binding protein that activates JNK and apoptosis

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SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family

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Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5

7 April 2017

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PML, a growth suppressor disrupted in acute promyelocytic leukemia

7 April 2017

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Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis

7 April 2017

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Identification of a novel nuclear domain

7 April 2017

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

7 April 2017

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

7 April 2017

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The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme

7 April 2017

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Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

7 April 2017

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PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

7 April 2017

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Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

7 April 2017

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PML is essential for multiple apoptotic pathways

7 April 2017

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Identification of three major sentrinization sites in PML

7 April 2017

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Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death

7 April 2017

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Covalent modification of PML by the sentrin family of ubiquitin-like proteins

7 April 2017

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Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region

7 April 2017

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The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1

7 April 2017

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

7 April 2017

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

7 April 2017

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

7 April 2017

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The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

7 April 2017

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The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells

28 September 2017

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The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its roles in the activation of gene expression and stimulation of virus replication.

28 September 2017

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PML induces a novel caspase-independent death process

28 September 2017

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Nuclear domain 10, the site of DNA virus transcription and replication

28 September 2017

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Segregation of transcription and replication sites into higher order domains

28 September 2017

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Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

28 September 2017

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The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms

28 September 2017

1 reference

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Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

28 September 2017

1 reference

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Human genes encoding U3 snRNA associate with coiled bodies in interphase cells and are clustered on chromosome 17p11.2 in a complex inverted repeat structure

28 September 2017

1 reference

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Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment

28 September 2017

1 reference

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Nuclear domain 10 (ND10) associated proteins are also present in nuclear bodies and redistribute to hundreds of nuclear sites after stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174231

Visualization of focal sites of transcription within human nuclei.

28 September 2017

1 reference

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HSV-1 IE protein Vmw110 causes redistribution of PML.

28 September 2017

1 reference

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Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

28 September 2017

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Characterization of N-myc amplification units in human neuroblastoma cells

28 September 2017

1 reference

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Associations between distinct pre-mRNA splicing components and the cell nucleus

28 September 2017

1 reference

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Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

28 September 2017

1 reference

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Nuclear domain 10 as preexisting potential replication start sites of herpes simplex virus type-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174231

Transplanted human neurons derived from a teratocarcinoma cell line (NTera-2) mature, integrate, and survive for over 1 year in the nude mouse brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174231

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174231

Disruption of PML-associated nuclear bodies during human cytomegalovirus infection

30 May 2018

1 reference

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Nuclear bodies as structural indicators of estrogenic stimulation in uterine luminal epithelial cells

30 May 2018

1 reference

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Antikinetochore and antitopoisomerase I antibodies in systemic scleroderma: comparative study using immunoblotted recombinant antigens, immunofluorescence, and double immunodiffusion.

30 May 2018

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A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

30 May 2018

1 reference

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Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.147.2.221

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1083%2FJCB.147.2.221

Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).

21 January 2018

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A novel nuclear substructure, ND10: distribution in normal and neoplastic human tissues

21 January 2018

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The acute promyelocytic leukaemia-associated PML gene is induced by interferon.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174231

Differing functional responses of simple and complex nuclear bodies in uterine luminal epithelial cells following estrogenic stimuli

28 November 2018

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12 December 2020

Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties

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12 December 2020

Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein

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12 December 2020

Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML)

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12 December 2020

U2 and U1 snRNA gene loci associate with coiled bodies

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12 December 2020

Identifiers

DOI

10.1083/JCB.147.2.221

1 reference

1440534

1440534

1 reference

1 reference

1 reference