Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C) (Q34732473)

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English	Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)	scientific article

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21 January 2020

Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C) (English)

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21 January 2020

toll-like receptor

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Mohamed L. Salem

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21 January 2020

Sabry A El-Naggar

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21 January 2020

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C Marcela Díaz-Montero

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21 January 2020

Amir A Al-Khami

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21 January 2020

Osama Naga

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21 January 2020

Alberto J Montero

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21 January 2020

Ahmed Khafagy

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21 January 2020

David J Cole

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21 January 2020

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1 February 2009

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21 January 2020

Journal of Immunology

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21 January 2020

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21 January 2020

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21 January 2020

2030-2040

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21 January 2020

Toll-like receptors in tumor immunotherapy

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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

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Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells

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7 July 2018

Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells

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7 July 2018

Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration

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7 July 2018

Adoptive immunotherapy for cancer: building on success

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7 July 2018

The multiple personalities of the chemokine receptor CCR7 in dendritic cells

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7 July 2018

The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity

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7 July 2018

CpG oligodeoxynucleotides activate dendritic cells in vivo and induce a functional and protective vaccine immunity against a TERT derived modified cryptic MHC class I-restricted epitope

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Interleukin-7-dependent expansion and persistence of melanoma-specific T cells in lymphodepleted mice lead to tumor regression and editing.

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Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

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7 July 2018

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

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7 July 2018

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

1 reference

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7 July 2018

Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell-based anti-tumor immunotherapy.

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7 July 2018

Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.

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7 July 2018

Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity

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7 July 2018

Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.

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7 July 2018

In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy

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7 July 2018

Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine

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7 July 2018

Induction of potent antitumor immunity by in situ targeting of intratumoral DCs.

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7 July 2018

Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses

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7 July 2018

Cell transfer therapy for cancer: lessons from sequential treatments of a patient with metastatic melanoma

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7 July 2018

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

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7 July 2018

Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease

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7 July 2018

Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells

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7 July 2018

Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice

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7 July 2018

Cyclophosphamide (Cy)-facilitated adoptive immunotherapy of a Cy-resistant tumour. Evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing suppressor T cells rather than by reducing tumour burden.

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7 July 2018

Cyclophosphamide and abrogation of tumor-induced suppressor T cell activity

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Origin of dendritic cells in peripheral lymphoid organs of mice.

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26 October 2018

Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity

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26 October 2018

Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.

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26 October 2018

Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity.

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26 October 2018

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

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26 October 2018

Irradiation up-regulates CD80 expression through two different mechanisms in spleen B cells, B lymphoma cells, and dendritic cells

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26 October 2018

The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-alpha production in CD11c+CD11b+CD8- dendritic cells

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Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors

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26 October 2018

Mobilization of dendritic cells in cancer patients treated with granulocyte colony-stimulating factor and chemotherapy

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26 October 2018

Cyclophosphamide induces the development of early myeloid cells suppressing tumor cell growth by a nitric oxide-dependent mechanism.

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26 October 2018

Persistence of clonal T-cell expansions following high-dose chemotherapy and autologous peripheral blood progenitor cell rescue.

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26 October 2018

Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer

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26 October 2018

Anamnestic responses induced by antigen persisting on follicular dendritic cells from cyclophosphamide-treated mice.

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26 October 2018

Alterations in dendritic cell phenotype and function associated with immunoenhancing effects of a subcutaneously administered cyclophosphamide derivative

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26 October 2018

Granulocyte-colony stimulating factor increases CD123hi blood dendritic cells with altered CD62L and CCR7 expression

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Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo manipulation of dendritic cells to induce therapeutic immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immature dendritic cells (CD11c+ CD3- B220- cells) present in mouse peripheral blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

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CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flt3 ligand induces tumor regression and antitumor immune responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine plasmacytoid dendritic cells produce IFN-gamma upon IL-4 stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No polarization of type 1 or type 2 precursor dendritic cells in peripheral blood stem cell collections of non-hodgkin's lymphoma patients mobilized with cyclophosphamide plus G-CSF, GM-CSF, or GM-CSF followed by G-CSF

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.4049/JIMMUNOL.0801829

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21 January 2020

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21 January 2020

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21 January 2020

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