Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice (Q39797630)

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scientific article published on January 1998

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English	Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice	scientific article published on January 1998

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scholarly article

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8 November 2019

Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice (English)

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8 November 2019

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8 November 2019

Filippo Belardelli

8

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8 November 2019

author name string

Proietti E

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8 November 2019

Greco G

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8 November 2019

Garrone B

3

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8 November 2019

Baccarini S

4

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8 November 2019

Venditti M

6

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8 November 2019

Carlei D

7

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8 November 2019

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publication date

1 January 1998

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8 November 2019

Journal of Clinical Investigation

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8 November 2019

101

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8 November 2019

429-441

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8 November 2019

2

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8 November 2019

Interaction of IFN alpha/beta with host cells essential to the early inhibition of Friend erythroleukemia visceral metastases in mice.

1 reference

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Effect of Cyclophosphamide on Immunological Control Mechanisms

1 reference

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Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-1+,2- T cells. Tumor eradication does not require participation of cytotoxic T cells

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22 September 2017

Host humoral and cellular immune mechanisms in the continued suppression of Friend erythroleukemia metastases after interferon alpha/beta treatment in mice

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Combined interleukin 1/interleukin 2 therapy of mice injected with highly metastatic Friend leukemia cells: host antitumor mechanisms and marked effects on established metastases

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Regulation of delayed-type hypersensitivity reactions by cyclophosphamide-sensitive T cells

1 reference

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22 September 2017

Splenic modifications induced by cyclophosphamide in C3H/He, nude, and "B" mice

1 reference

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22 September 2017

Regulation of specific cell-mediated cytotoxic response against SV40-induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice

1 reference

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Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. I. Rapid evolution of encephalomyocarditis virus infection

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Effect of autolymphocyte therapy on survival and quality of life in patients with metastatic renal-cell carcinoma

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Induction of bystander T cell proliferation by viruses and type I interferon in vivo

1 reference

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15 June 2018

Isolation and characterization of a metastatic Eb-like tumor variant highly responsive to interleukin (IL)-2 and to combination cytokine therapy with IL-2/IL-1 beta and IL-1 beta/interferon-alpha/beta.

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15 June 2018

Adoptive transfer of ex vivo-activated memory T-cell subsets with cyclophosphamide provides effective tumor-specific chemoimmunotherapy of advanced metastatic murine melanoma and carcinoma.

1 reference

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15 June 2018

The essential role of endogenous IFN alpha/beta in the anti-metastatic action of sensitized T lymphocytes in mice injected with Friend erythroleukemia cells.

1 reference

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15 June 2018

In vitro sensitization and expansion with viable tumor cells and interleukin 2 in the generation of specific therapeutic effector cells

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15 June 2018

Chemo-immunotherapy of murine tumors using interleukin-2 (IL-2) and cyclophosphamide. IL-2 can facilitate or inhibit tumor growth depending on the sequence of treatment and the tumor type

1 reference

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15 June 2018

Therapeutic efficacy of human recombinant interleukin-2 (TGP-3) alone or in combination with cyclophosphamide and immunocompetent cells in allogeneic, semi-syngeneic, and syngeneic murine tumors

1 reference

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15 June 2018

Cyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: a consequence of eliminating precursor L3T4+ suppressor T-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

15 June 2018

Cyclophosphamide and abrogation of tumor-induced suppressor T cell activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

15 June 2018

Chemo-immunotherapy of murine solid tumors: enhanced therapeutic effects by interleukin-2 combined with interferon alpha and the role of specific T cells.

1 reference

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15 June 2018

Adoptive chemoimmunotherapy using ex vivo activated memory T-cells and cyclophosphamide: tumor lysis syndrome of a metastatic soft tissue sarcoma.

1 reference

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Antigen-independent activation of naive and memory resting T cells by a cytokine combination

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Adoptively transferred ex vivo activated memory T cells with cyclophosphamide: effective tumor-specific chemoimmunotherapy of advanced metastatic murine melanoma and carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

20 August 2018

Autolymphocyte therapy. II. Dependence of in vivo anti-tumor specificity and long-term immunity against murine melanoma and carcinoma on ex vivo activated donor memory T-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

20 August 2018

Autolymphocyte therapy--I. In vivo tumour-specific adoptive cellular therapy of murine melanoma and carcinoma using ex vivo activated memory T-lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

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Adoptive transfer of ex vivo activated memory T-cells with or without cyclophosphamide for advanced metastatic melanoma: results in 36 patients.

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20 August 2018

Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. II. Role of host mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

20 August 2018

Anti-tumor effects of interleukin-2 and interleukin-1 in mice transplanted with different syngeneic tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508583

20 August 2018

Combined interleukin 1 beta/interleukin 2 treatment in mice: synergistic myelostimulatory activity and protection against cyclophosphamide-induced myelosuppression

1 reference

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Combined interleukin-1 beta/interleukin-6 treatment in mice: synergistic myelostimulatory activity and myelorestorative effect after cyclophosphamide-induced myelosuppression

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1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

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Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interference of anti-tumor and immunosuppressive effects of cyclophosphamide in tumor-bearing rats. Analysis of factors determining resistance or susceptibility to a subsequent tumor challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy by using cyclophosphamide and tumor-sensitized lymphocytes: a possible mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon treatment markedly inhibits the development of tumor metastases in the liver and spleen and increases survival time of mice after intravenous inoculation of Friend erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-interferon gene transfer into metastatic Friend leukemia cells abrogated tumorigenicity in immunocompetent mice: antitumor therapy by means of interferon-producing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cure of mice bearing a late-stage, highly metastatic, drug-resistant tumor by adoptive chemoimmunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulation of interleukin-2 by cyclophosphamide: a phase IB trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elimination of CD4+ T cells in mice bearing an advanced sarcoma augments the antitumor action of interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autologous stem cell transplantation: release of early and late acting growth factors relates with hematopoietic ablation and recovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

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based on heuristic

inferred from PubMed ID database lookup

High cell kinetics is associated with amplification of the int-2, bcl-1, myc and erbB-2 proto-oncogenes and loss of heterozygosity at the DF3 locus in primary breast cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance in timing of cyclophosphamide on the enhancement of interleukin-2-induced cytolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host immune potentiation of drug responses to a murine mammary adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta induces tumor necrosis and early morphologic and metabolic changes in transplantable mouse tumors. Similarities with the anti-tumor effects of tumor necrosis factor alpha or beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of host antitumor immunity by low doses of cyclophosphamide and mafosfamide in two animal tumor models

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend erythroleukemia cells. VIII. Role of the immune system in the inhibition of visceral metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elimination of cycling CD4+ suppressor T cells with an anti-mitotic drug releases non-cycling CD8+ T cells to cause regression of an advanced lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic anti-tumor effects of combined IL-1/IFN-alpha/beta therapy in mice injected with metastatic Friend erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9435316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI1348

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9435316%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9435316%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9435316%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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