Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration (Q34718036)

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English	Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration (English)

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Europe PubMed Central

4 August 2017

1 reference

based on heuristic

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based on heuristic

inferred from title

Rosemary O'Connor

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Rosemary O'Connor

5

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ORCID Public Data File 2021

author name string

Patrick A Kiely

1

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Europe PubMed Central

4 August 2017

Denise O'Gorman

2

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Europe PubMed Central

4 August 2017

Ken Luong

3

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Europe PubMed Central

4 August 2017

Dorit Ron

4

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Europe PubMed Central

4 August 2017

language of work or name

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publication date

1 June 2006

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Europe PubMed Central

4 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

4 August 2017

26

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Europe PubMed Central

4 August 2017

4041-4051

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Europe PubMed Central

4 August 2017

11

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Europe PubMed Central

4 August 2017

beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts

1 reference

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Dimerize RACK1 upon transformation with oncogenic ras.

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RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251.

1 reference

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Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A.

1 reference

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Requirement of protein phosphatase 2A for recruitment of IQGAP1 to Rac-bound beta1 integrin

1 reference

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Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells

1 reference

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Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes

1 reference

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Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.

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Reduced expression of the regulatory A subunit of serine/threonine protein phosphatase 2A in human breast cancer MCF-7 cells

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Minireview: Integral Membrane Proteins that Function Coordinately with the Insulin-Like Growth Factor I Receptor to Regulate Intracellular Signaling

1 reference

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RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site

1 reference

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The RACK1 scaffold protein: a dynamic cog in cell response mechanisms

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Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.

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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling

1 reference

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RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix

1 reference

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Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

1 reference

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Distinct and overlapping functions of insulin and IGF-I receptors

1 reference

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Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells

1 reference

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Insulin-like growth factor axis during embryonic development

1 reference

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RACK1 is up-regulated in angiogenesis and human carcinomas

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RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells

1 reference

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Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit

1 reference

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The WD protein Rack1 mediates protein kinase C and integrin-dependent cell migration.

1 reference

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Identifiers

10.1128/MCB.01868-05

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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