Aging induces a distinct gene expression program in mouse islets (Q34706953)

4 August 2017

Aging induces a distinct gene expression program in mouse islets (English)

1 reference

4 August 2017

Matthew M Rankin

1

1 reference

PubMed ID

21099336

4 August 2017

Jake A Kushner

series ordinal

2

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4 August 2017

1 November 2010

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4 August 2017

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4 August 2017

2

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4 August 2017

6

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4 August 2017

345-352

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PubMed ID

21099336

describes a project that uses

4 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3062249

inferred from PubMed Central ID database lookup

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Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating

7 July 2018

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HOP is a monomer: investigation of the oligomeric state of the co-chaperone HOP.

7 July 2018

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Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

7 July 2018

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Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration

7 July 2018

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Cyclin D2 protein stability is regulated in pancreatic beta-cells

7 July 2018

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Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus.

7 July 2018

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Adaptive beta-cell proliferation is severely restricted with advanced age.

7 July 2018

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Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice

7 July 2018

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Directing cell differentiation with small-molecule histone deacetylase inhibitors: the example of promoting pancreatic endocrine cells

7 July 2018

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An extensive genetic program occurring during postnatal growth in multiple tissues

7 July 2018

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Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse

7 July 2018

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Minireview: pancreatic progenitor cells--recent studies

7 July 2018

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UHRF1 plays a role in maintaining DNA methylation in mammalian cells

7 July 2018

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

7 July 2018

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Genome regulation by polycomb and trithorax proteins

7 July 2018

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FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults

7 July 2018

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Developmental roles of the BMP1/TLD metalloproteinases.

7 July 2018

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

7 July 2018

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Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

7 July 2018

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

7 July 2018

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Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG

7 July 2018

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Identification of two novel components of the human NDC80 kinetochore complex

7 July 2018

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Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells

7 July 2018

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Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1

7 July 2018

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A Smad transcriptional corepressor

7 July 2018

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DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

7 July 2018

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Epigenetic modification and uniparental inheritance of H19 in Beckwith-Wiedemann syndrome

7 July 2018

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Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters

7 July 2018

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A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif

7 July 2018

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Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion

7 July 2018

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Growth and regeneration of adult beta cells does not involve specialized progenitors.

7 July 2018

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Partial pancreatectomy in adult humans does not provoke beta-cell regeneration

21 January 2018

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Very slow turnover of beta-cells in aged adult mice

21 January 2018

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The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation.

21 January 2018

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Defining pancreatic endocrine precursors and their descendants

21 January 2018

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The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.

21 January 2018

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https://api.crossref.org/works/10.4161%2FISL.2.6.13376

Islet neogenesis-associated protein pentadecapeptide (INGAP-PP): mechanisms involved in its effect upon beta-cell mass and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FISL.2.6.13376

Reciprocal modulation of adult beta cell maturity by activin A and follistatin

21 January 2018

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https://api.crossref.org/works/10.4161%2FISL.2.6.13376

A direct approach to false discovery rates

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FISL.2.6.13376

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062249

Gene Expression Analysis in Diabetes Research

26 October 2018

1 reference

https://api.crossref.org/works/10.4161%2FISL.2.6.13376

Expanding human beta cells

21 January 2018

1 reference

12 December 2020

Increased Islet Volume but Unchanged Islet Number in ob/ob Mice

1 reference

12 December 2020

Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat

1 reference

12 December 2020

Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation

1 reference

12 December 2020

Metabolic diapause in pancreatic beta-cells expressing a gain-of-function mutant of the forkhead protein Foxo1

1 reference

12 December 2020

Identifiers

DOI

10.4161/ISL.2.6.13376

1 reference

4 August 2017

1 reference

4 August 2017

1 reference

PubMed ID

21099336