CGP7930: a positive allosteric modulator of the GABAB receptor. (Q34693009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

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title

CGP7930: a positive allosteric modulator of the GABAB receptor (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

C L Adams

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

A J Lawrence

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

publication date

1 January 2007

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

CNS Neuroscience & Therapeutics

8 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

13

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8 January 2020

issue

3

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8 January 2020

page(s)

308-316

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Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Molecular diversity, trafficking and subcellular localization of GABAB receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

GABAB receptors and their significance in mammalian pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Suppression of symptoms of alcohol dependence and craving using high-dose baclofen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

GABA(B) receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Baclofen for alcohol dependence: a preliminary open-label study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The positive allosteric modulator GS39783 enhances GABA(B) receptor-mediated inhibition of cyclic AMP formation in rat striatum in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

GABA(B) receptors and synaptic modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Allosteric modulation of GABA(B) receptor function in human frontal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Positive regulation of GABA(B) receptors dually coupled to cyclic AMP by the allosteric agent CGP7930.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The GABA B receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Mechanisms of allosteric modulation at GABAB receptors by CGP7930 and GS39783: effects on affinities and efficacies of orthosteric ligands with distinct intrinsic properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Differential compartmentalization and distinct functions of GABAB receptor variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00021.X

Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

21 January 2018

1 reference

12 December 2020

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

1 reference

12 December 2020

GABAB receptor activation partially inhibits N-methyl-D-aspartate-mediated tyrosine hydroxylase stimulation in rat striatal slices

1 reference

12 December 2020

Selected amino acids, dipeptides and arylalkylamine derivatives do not act as allosteric modulators at GABAB receptors.

1 reference

12 December 2020

Activation mechanism of the heterodimeric GABA(B) receptor

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12 December 2020

Molecular mechanisms of GABA(B) receptor activation: new insights from the mechanism of action of CGP7930, a positive allosteric modulator.

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12 December 2020

Reducing effect of the positive allosteric modulators of the GABA(B) receptor, CGP7930 and GS39783, on alcohol intake in alcohol-preferring rats

1 reference

12 December 2020

GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors

1 reference

12 December 2020

Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam

1 reference

12 December 2020

Differential modulation by the GABAB receptor allosteric potentiator 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)-phenol (CGP7930) of synaptic transmission in the rat hippocampal CA1 area

1 reference

12 December 2020

Characterization of the binding of [3H]CGP54626 to GABAB receptors in the male bullfrog (Rana catesbeiana).

1 reference

12 December 2020

Baclofen-induced suppression of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats exposed to different alcohol concentrations

1 reference

12 December 2020

GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation.

1 reference

12 December 2020

10.1111/J.1527-3458.2007.00021.X

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17894647%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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