The positive allosteric modulator GS39783 enhances GABA(B) receptor-mediated inhibition of cyclic AMP formation in rat striatum in vivo (Q46915132)

26 December 2017

title

The positive allosteric modulator GS39783 enhances GABA(B) receptor-mediated inhibition of cyclic AMP formation in rat striatum in vivo (English)

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26 December 2017

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Tina Gjoni

1

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26 December 2017

Sandrine Desrayaud

series ordinal

2

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26 December 2017

Stefan Imobersteg

series ordinal

3

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26 December 2017

Stephan Urwyler

series ordinal

4

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26 December 2017

language of work or name

English

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publication date

25 January 2006

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26 December 2017

Journal of Neurochemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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26 December 2017

volume

96

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26 December 2017

issue

5

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26 December 2017

page(s)

1416-1422

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26 December 2017

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

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In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor

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GABA(B) receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area

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21 January 2018

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Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

21 January 2018

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Activation of nigral dopamine neurons by the selective GABA(B)-receptor antagonist SCH 50911.

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Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

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21 January 2018

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Positive regulation of GABA(B) receptors dually coupled to cyclic AMP by the allosteric agent CGP7930.

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N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

21 January 2018

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Mechanisms of allosteric modulation at GABAB receptors by CGP7930 and GS39783: effects on affinities and efficacies of orthosteric ligands with distinct intrinsic properties.

21 January 2018

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GABA(B) receptors as potential therapeutic targets

21 January 2018

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10.1111/J.1471-4159.2006.03660.X

21 January 2018

Identifiers

DOI

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26 December 2017

PubMed ID

16441514

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26 December 2017