Gene delivery by lentivirus vectors (Q34688367)

3 August 2017

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title

Gene delivery by lentivirus vectors (English)

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3 August 2017

Adam S Cockrell

1

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PubMed ID

17873406

3 August 2017

Tal Kafri

series ordinal

2

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3 August 2017

1 July 2007

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3 August 2017

Molecular Biotechnology

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3 August 2017

36

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3 August 2017

184-204

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3 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s12033-007-0010-8

3 August 2017

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cites work

Gene therapy for neurodegenerative and ocular diseases using lentiviral vectors

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12033-007-0010-8

Production and concentration of pseudotyped HIV-1-based gene transfer vectors

21 January 2018

1 reference

12 December 2020

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

1 reference

12 December 2020

Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

1 reference

12 December 2020

HIV-1 genome nuclear import is mediated by a central DNA flap

1 reference

12 December 2020

Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain

1 reference

12 December 2020

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

1 reference

12 December 2020

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.

1 reference

12 December 2020

A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia

1 reference

12 December 2020

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

1 reference

12 December 2020

Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

1 reference

12 December 2020

Development of a sensitive assay for detection of replication-competent recombinant lentivirus in large-scale HIV-based vector preparations

1 reference

12 December 2020

High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients

1 reference

12 December 2020

Second-generation shRNA libraries covering the mouse and human genomes

1 reference

12 December 2020

A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene

1 reference

12 December 2020

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

12 December 2020

Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels

1 reference

12 December 2020

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

1 reference

12 December 2020

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

1 reference

12 December 2020

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

1 reference

12 December 2020

Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector

1 reference

12 December 2020

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

1 reference

12 December 2020

A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors

1 reference

12 December 2020

Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells

1 reference

12 December 2020

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

1 reference

12 December 2020

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G.

1 reference

12 December 2020

Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells

1 reference

12 December 2020

Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1

1 reference

12 December 2020

Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines

1 reference

12 December 2020

Cre-lox-regulated conditional RNA interference from transgenes

1 reference

12 December 2020

HIV-1 vectors: fulfillment of expectations, further advancements, and still a way to go.

1 reference

12 December 2020

Lentiviral-mediated RNA interference

1 reference

12 December 2020

Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector

1 reference

12 December 2020

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

1 reference

12 December 2020

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

1 reference

12 December 2020

A new-generation stable inducible packaging cell line for lentiviral vectors

1 reference

12 December 2020

Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: association with dementia and multinucleated giant cells in the brains of patients with AIDS.

1 reference

12 December 2020

VSV-G pseudotyped lentiviral vector particles produced in human cells are inactivated by human serum

1 reference

12 December 2020

Gene transfer of a chimeric trans-activator is immunogenic and results in short-lived transgene expression

1 reference

12 December 2020

A single-LTR HIV-1 vector optimized for functional genomics applications

1 reference

12 December 2020

Human immunodeficiency virus infection of cells arrested in the cell cycle

1 reference

12 December 2020

Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors

1 reference

12 December 2020

Silencing and variegation of gammaretrovirus and lentivirus vectors

1 reference

12 December 2020

In Vivo Transduction by Intravenous Injection of a Lentiviral Vector Expressing Human ADA into Neonatal ADA Gene Knockout Mice: A Novel Form of Enzyme Replacement Therapy for ADA Deficiency

1 reference

12 December 2020

Construction and molecular analysis of gene transfer systems derived from bovine immunodeficiency virus

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12 December 2020

Kinetic analyses of stability of simple and complex retroviral vectors

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12 December 2020

Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction

1 reference

12 December 2020

A third-generation lentivirus vector with a conditional packaging system

1 reference

12 December 2020

Gene transfer systems derived from Visna virus: analysis of virus production and infectivity

1 reference

12 December 2020

Altering the tropism of lentiviral vectors through pseudotyping

1 reference

12 December 2020

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

1 reference

12 December 2020

Comparison of lentiviral vector titration methods

1 reference

12 December 2020

Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosis

1 reference

12 December 2020

Efficient production of germline transgenic chickens using lentiviral vectors

1 reference

12 December 2020

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells

1 reference

12 December 2020

Development of multigene and regulated lentivirus vectors

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12 December 2020

Silencing of HIV-1 with RNA interference: a multiple shRNA approach

1 reference

12 December 2020

Upscaling of lentiviral vector production by tangential flow filtration

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12 December 2020

Genome-scale loss-of-function screening with a lentiviral RNAi library

1 reference

12 December 2020

Downstream processing of oncoretroviral and lentiviral gene therapy vectors

1 reference

12 December 2020

Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

1 reference

12 December 2020

Certification assays for HIV-1-based vectors: frequent passage of gag sequences without evidence of replication-competent viruses

1 reference

12 December 2020

Gene transfer vectors derived from equine infectious anemia virus

1 reference

12 December 2020

microPrimer: the biogenesis and function of microRNA.

1 reference

12 December 2020

Generation of tissue-specific transgenic birds with lentiviral vectors

1 reference

12 December 2020

Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure

1 reference

12 December 2020

Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection

1 reference

12 December 2020

Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors

1 reference

12 December 2020

Real-time quantitative PCR for the design of lentiviral vector analytical assays

1 reference

12 December 2020

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

1 reference

12 December 2020

Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells

1 reference

12 December 2020

Reduced mobilization of Rev-responsive element-deficient lentiviral vectors

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12 December 2020

Stable suppression of tumorigenicity by virus-mediated RNA interference

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12 December 2020

Continuous high-titer HIV-1 vector production.

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12 December 2020

Harnessing HIV for therapy, basic research and biotechnology

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12 December 2020

Integration complexes derived from HIV vectors for rapid assays in vitro

1 reference

12 December 2020

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

12 December 2020

Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer

1 reference

12 December 2020

Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infection.

1 reference

12 December 2020

A packaging cell line for lentivirus vectors.

1 reference

12 December 2020

Successful correction of the human Cooley's anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator

1 reference

12 December 2020

Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants

1 reference

12 December 2020

Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter

1 reference

12 December 2020

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

1 reference

12 December 2020

Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles

1 reference

12 December 2020

The central DNA flap of the human immunodeficiency virus type 1 is important for viral replication

1 reference

12 December 2020

Effective expression of small interfering RNA in human cells

1 reference

12 December 2020

Real-Time Quantitative Reverse Transcriptase-Polymerase Chain Reaction as a Method for Determining Lentiviral Vector Titers and Measuring Transgene Expression

1 reference

12 December 2020

Development of a self-inactivating lentivirus vector.

1 reference

12 December 2020

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1 reference

12 December 2020

Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences

1 reference

12 December 2020

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

1 reference

12 December 2020

Retroviral infection of non-dividing cells: old and new perspectives

1 reference

12 December 2020

Nuclear import defect of human immunodeficiency virus type 1 DNA flap mutants is not dependent on the viral strain or target cell type

1 reference

12 December 2020

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

1 reference

12 December 2020

A stable system for the high-titer production of multiply attenuated lentiviral vectors

1 reference

12 December 2020

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

12 December 2020

Vaccination of mice with replication-defective human immunodeficiency virus induces cellular and humoral immunity and protects against vaccinia virus-gag challenge

1 reference

12 December 2020

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

1 reference

12 December 2020

A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract.

1 reference

12 December 2020

Mutational analysis of the vesicular stomatitis virus glycoprotein G for membrane fusion domains

1 reference

12 December 2020

Production of transgenic rats by lentiviral transduction of male germ-line stem cells

1 reference

12 December 2020

HIV-1 gene expression: lessons from provirus and non-integrated DNA

1 reference

12 December 2020

An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity

1 reference

12 December 2020

Genotoxicity of retroviral integration in hematopoietic cells.

1 reference

12 December 2020

Integration by design

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12 December 2020

Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods

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12 December 2020

Integration site selection by lentiviruses: biology and possible control

1 reference

12 December 2020

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

1 reference

12 December 2020

Human immunodeficiency virus type 2 lentivirus vectors for gene transfer: expression and potential for helper virus-free packaging

1 reference

12 December 2020

Comparison of transfection conditions for a lentivirus vector produced in large volumes

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12 December 2020

Workshop on long-term follow-up of participants in human gene transfer research

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12 December 2020

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

1 reference

12 December 2020

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

1 reference

12 December 2020

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

12 December 2020

Immune responses against tetracycline-dependent transactivators affect long-term expression of mouse erythropoietin delivered by a helper-dependent adenoviral vector

1 reference

12 December 2020

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo

1 reference

12 December 2020

Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified trip lentiviral vectors

1 reference

12 December 2020

HIV-1 reverse transcription. A termination step at the center of the genome

1 reference

12 December 2020

HIV-1 infection requires a functional integrase NLS.

1 reference

12 December 2020

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

12 December 2020

Use of RNA polymerase II to transcribe artificial microRNAs.

1 reference

12 December 2020

Comparison of wild-type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium

1 reference

12 December 2020

Lentivirus-mediated gene transfer to the central nervous system: therapeutic and research applications

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12 December 2020

Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection.

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12 December 2020

Human immunodeficiency virus type 1 vectors with alphavirus envelope glycoproteins produced from stable packaging cells.

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12 December 2020

A versatile tool for conditional gene expression and knockdown

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12 December 2020

Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A.

1 reference

12 December 2020

Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging.

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12 December 2020

Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap

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12 December 2020

Gene transfer in humans using a conditionally replicating lentiviral vector

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12 December 2020

The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.

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12 December 2020

Transcriptional activation by tetracyclines in mammalian cells

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12 December 2020

Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses

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12 December 2020

Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters.

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12 December 2020

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

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12 December 2020

Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

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12 December 2020

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

1 reference

12 December 2020

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

1 reference

12 December 2020

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

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12 December 2020

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

1 reference

12 December 2020

Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication

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12 December 2020

Gene therapy put on hold as third child develops cancer

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12 December 2020

siRNA-mediated gene silencing in vitro and in vivo.

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12 December 2020

In vivo evaluation of an EIAV vector for the systemic genetic delivery of therapeutic antibodies

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12 December 2020

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

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12 December 2020

Integrated self-inactivating lentiviral vectors produce full-length genomic transcripts competent for encapsidation and integration

1 reference

12 December 2020

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy

1 reference

12 December 2020

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors

1 reference

12 December 2020

The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells

1 reference

12 December 2020

Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE).

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12 December 2020

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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12 December 2020

Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1.

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12 December 2020

Effective gene therapy with nonintegrating lentiviral vectors

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12 December 2020

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import

1 reference

12 December 2020

Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus

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12 December 2020

HLA-A*0201-restricted cytolytic responses to the rtTA transactivator dominant and cryptic epitopes compromise transgene expression induced by the tetracycline on system.

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12 December 2020

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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12 December 2020

Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice

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12 December 2020

Development of ecdysone-regulated lentiviral vectors

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12 December 2020

Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells.

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12 December 2020

Efficient generation of transgenic pigs using equine infectious anaemia virus (EIAV) derived vector.

1 reference

12 December 2020

Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus

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12 December 2020

Prospects and implications of using chromatin insulators in gene therapy and transgenesis

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12 December 2020

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

1 reference

12 December 2020

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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12 December 2020

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

1 reference

12 December 2020

Novel integrase-defective lentiviral episomal vectors for gene transfer

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12 December 2020

Production of trans-lentiviral vector with predictable safety.

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12 December 2020

The genetic engineering of hematopoietic stem cells: the rise of lentiviral vectors, the conundrum of the ltr, and the promise of lineage-restricted vectors

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12 December 2020

Reducing mobilization of simian immunodeficiency virus based vectors by primer complementation

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12 December 2020

Development of a novel trans-lentiviral vector that affords predictable safety

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12 December 2020

Efficient transgenesis in farm animals by lentiviral vectors

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12 December 2020

A resource for large-scale RNA-interference-based screens in mammals.

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12 December 2020

Transactivator and structurally optimized inducible lentiviral vectors

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12 December 2020

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

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12 December 2020

A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer

1 reference

12 December 2020

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

1 reference

12 December 2020

Lentiviral-mediated delivery of siRNAs for antiviral therapy

1 reference

12 December 2020

CRE recombinase-inducible RNA interference mediated by lentiviral vectors

1 reference

12 December 2020

Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression

1 reference

12 December 2020

Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus

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12 December 2020

Report from the 2nd Stem Cell Clonality and Genotoxicity Retreat: St. Louis, MO, June 1, 2005

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12 December 2020

Correction of sickle cell disease in transgenic mouse models by gene therapy

1 reference

12 December 2020

Selection of novel vesicular stomatitis virus glycoprotein variants from a peptide insertion library for enhanced purification of retroviral and lentiviral vectors

1 reference

12 December 2020

Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

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12 December 2020

Generation of transgenic cattle by lentiviral gene transfer into oocytes.

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12 December 2020

Transient gene expression by nonintegrating lentiviral vectors

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12 December 2020

Lentiviral vectors: regulated gene expression

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12 December 2020

Exposure of lentiviral vectors to subneutral pH shifts the tropism from Purkinje cell to Bergmann glia.

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12 December 2020

Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector

1 reference

12 December 2020

Self-inactivating lentiviral vectors with U3 and U5 modifications.

1 reference

12 December 2020

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness

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12 December 2020

Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery

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12 December 2020

Gene transfer system derived from the caprine arthritis-encephalitis lentivirus

1 reference

12 December 2020

An inducible packaging cell system for safe, efficient lentiviral vector production in the absence of HIV-1 accessory proteins

1 reference

12 December 2020

PEGylation of a vesicular stomatitis virus G pseudotyped lentivirus vector prevents inactivation in serum

1 reference

12 December 2020

Lentivirus vector mobilization and spread by human immunodeficiency virus

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12 December 2020

Targeting lentiviral vectors to specific cell types in vivo

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12 December 2020

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

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12 December 2020

10.1007/S12033-007-0010-8

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

17873406