Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs (Q34653531)

3 August 2017

Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs (English)

1 reference

3 August 2017

1 reference

Andrew Churg

1

1 reference

3 August 2017

Rona Wang

2

1 reference

3 August 2017

Xiaoshan Wang

3

1 reference

3 August 2017

Per-Ola Onnervik

4

1 reference

3 August 2017

Kerstin Thim

5

1 reference

3 August 2017

Joanne L Wright

6

1 reference

3 August 2017

language of work or name

English

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publication date

20 February 2007

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3 August 2017

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3 August 2017

62

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3 August 2017

8

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3 August 2017

706-713

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The electrophoretic α1-globulin pattern of serum in α1-antitrypsin deficiency. 1963.

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Elastin fragments drive disease progression in a murine model of emphysema

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Elevated MMP-12 protein levels in induced sputum from patients with COPD.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

A distinctive alveolar macrophage activation state induced by cigarette smoking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

The nature of small-airway obstruction in chronic obstructive pulmonary disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Matrilysin-dependent elastolysis by human macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Alveolar wall apoptosis causes lung destruction and emphysematous changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Matrix metalloproteinase-9 in lung remodeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Metalloproteinase and growth factor interactions: do they play a role in pulmonary fibrosis?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Remodeling in asthma and chronic obstructive lung disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Inhaled recombinant alpha 1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

An inhaled matrix metalloprotease inhibitor prevents cigarette smoke-induced emphysema in the mouse

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Matrix Metalloproteinases Inhibition Attenuates Tobacco Smoke-Induced Emphysema in Guinea Pigs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Apoptosis and emphysema: the missing link.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

α-1-Antitrypsin Ameliorates Cigarette Smoke–induced Emphysema in the Mouse

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Progressive adult-onset emphysema in transgenic mice expressing human MMP-1 in the lung.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Metalloproteinase inhibition by Batimastat attenuates pulmonary hypertension in chronically hypoxic rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117295

Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD

26 October 2018

1 reference

12 December 2020

Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema

1 reference

12 December 2020

Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease

1 reference

12 December 2020

Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release

1 reference

12 December 2020

Levels of elastase activity in bronchoalveolar lavage fluids of healthy smokers and nonsmokers

1 reference

12 December 2020

Cigarette smoke causes physiologic and morphologic changes of emphysema in the guinea pig

1 reference

12 December 2020

Effect of long-term cigarette smoke exposure on pulmonary vascular structure and function in the guinea pig

1 reference

12 December 2020

Effect of smoking cessation on pulmonary and cardiovascular function and structure: analysis of guinea pig model

1 reference

12 December 2020

Mineral dusts cause elastin and collagen breakdown in the rat lung: a potential mechanism of dust-induced emphysema

1 reference

12 December 2020

Matrix metalloproteinase expression and production by alveolar macrophages in emphysema

1 reference

12 December 2020

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

1 reference

12 December 2020

Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema

1 reference

12 December 2020

EXPERIMENTAL EMPHYSEMA: ITS PRODUCTION WITH PAPAIN IN NORMAL AND SILICOTIC RATS

1 reference

12 December 2020

Correlation of lung surface area to apoptosis and proliferation in human emphysema

1 reference

12 December 2020

Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha1-antitrypsin

1 reference

12 December 2020

Identifiers

DOI

10.1136/THX.2006.068353

1 reference

3 August 2017

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3 August 2017

1 reference