Metalloproteinase inhibition by Batimastat attenuates pulmonary hypertension in chronically hypoxic rats (Q44382897)

2 December 2017

Metalloproteinase inhibition by Batimastat attenuates pulmonary hypertension in chronically hypoxic rats (English)

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2 December 2017

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pulmonary hypertension

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6

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2 December 2017

Jan Herget

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Jana Novotna

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2 December 2017

Jana Bibova

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2 December 2017

Viera Povysilova

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2 December 2017

Marie Vankova

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28 March 2003

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American Journal of Physiology - Lung Cellular and Molecular Physiology

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285

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2 December 2017

L199-208

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Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

2 December 2017

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Changes in the composition and metabolism of arterial collagens during the development of pulmonary hypertension in rabbits

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Matrix metalloproteinase inhibitors: present achievements and future prospects

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Ventricular weight in cardiac hypertrophy

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Collagen breakdown products and lung collagen metabolism: an in vitro study on fibroblast cultures

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Phase I trial of the matrix metalloproteinase inhibitor BAY12-9566 in patients with advanced solid tumors

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Resolution of pulmonary hypertension and other features induced by chronic hypoxia in rats during complete and intermittent normoxia

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Extracellular matrix remodeling in the vascular wall

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

The role of plasminogen, plasminogen activators, and matrix metalloproteinases in primate arterial smooth muscle cell migration.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

MMP inhibition modulates TNF-alpha transgenic mouse phenotype early in the development of heart failure

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Pulmonary vascular adaptations to augmented polycythemia during chronic hypoxia.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

An antifibrotic agent reduces blood pressure in established pulmonary hypertension in the rat.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Structure and function in pulmonary hypertension. New perceptions

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth-muscle cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Mast cell collagenase correlates with regression of pulmonary vascular remodeling in the rat.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Extracellular matrix remodeling during morphogenesis.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

Angiotensin II receptor expression and inhibition in the chronically hypoxic rat lung

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00167.2002

10.1152/AJPLUNG.00167.2002

21 January 2018

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2 December 2017

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