Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy (Q34642189)

3 August 2017

Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy (English)

1 reference

3 August 2017

1 reference

6

Gen Sobue

1 reference

3 August 2017

Carlo Rinaldi

1

1 reference

3 August 2017

Laura C Bott

2

1 reference

3 August 2017

Ke-lian Chen

3

1 reference

3 August 2017

George G Harmison

4

1 reference

3 August 2017

Masahisa Katsuno

5

1 reference

3 August 2017

Maria Pennuto

7

1 reference

3 August 2017

Kenneth H Fischbeck

8

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3 August 2017

language of work or name

English

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publication date

6 December 2012

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3 August 2017

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3 August 2017

18

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3 August 2017

1261-1268

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Creative Commons Attribution 4.0 International

3 August 2017

start time

29 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3521783/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.2119/molmed.2012.00271

0 references

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Neurotoxic effects of androgens in spinal and bulbar muscular atrophy.

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Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial.

7 July 2018

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Native functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy

7 July 2018

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Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial

7 July 2018

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Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation

7 July 2018

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Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice

7 July 2018

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Clinical features of spinal and bulbar muscular atrophy

7 July 2018

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Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy

7 July 2018

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Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

7 July 2018

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Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease.

7 July 2018

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Trinucleotide Repeat Disorders

7 July 2018

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Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model

7 July 2018

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

7 July 2018

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Aggregation and proteasome: the case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy.

7 July 2018

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

7 July 2018

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Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

7 July 2018

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Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.

7 July 2018

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Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons

7 July 2018

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Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait

7 July 2018

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Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors

7 July 2018

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Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

7 July 2018

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X-linked spinomuscular atrophy: a kindred with associated abnormal androgen receptor binding

7 July 2018

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The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons

7 July 2018

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Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophy

7 July 2018

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Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

7 July 2018

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Spinal and bulbar muscular atrophy: skeletal muscle pathology in male patients and heterozygous females.

26 October 2018

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Effects of combined recombinant insulin-like growth factor (IGF)-I and IGF binding protein-3 in type 2 diabetic patients on glycemic control and distribution of IGF-I and IGF-II among serum binding protein complexes.

26 October 2018

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Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy

26 October 2018

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Pharmacokinetic studies of recombinant human insulin-like growth factor I (rhIGF-I)/rhIGF-binding protein-3 complex administered to patients with growth hormone insensitivity syndrome

26 October 2018

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Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.

26 October 2018

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Bulbospinal muscular atrophy: Kennedy's disease.

26 October 2018

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Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

26 October 2018

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Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice

26 October 2018

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Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521783

Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adults

9 December 2018

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00271

Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00271

Co-administration of IGF-I and glycosaminoglycans greatly delays motor neurone disease and affects IGF-I expression in the wobbler mouse: a long-term study

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00271

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00271

A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00271

10.2119/MOLMED.2012.00271

31 March 2020

Identifiers

DOI

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Dimensions Publication ID

3 August 2017

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3 August 2017

1 reference