Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage (Q34638026)

3 August 2017

Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage (English)

1 reference

3 August 2017

0 references

1 reference

Hongmei Luo

1

1 reference

3 August 2017

Aimin Yang

2

1 reference

3 August 2017

Bradley A Schulte

3

1 reference

3 August 2017

Michael J Wargovich

4

1 reference

3 August 2017

Gavin Y Wang

5

1 reference

3 August 2017

language of work or name

English

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publication date

22 March 2013

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3 August 2017

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3 August 2017

8

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3 August 2017

3

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3 August 2017

e60065

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

start time

22 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines

7 July 2018

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7 July 2018

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Chemosensitization of tumors by resveratrol

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Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3.

7 July 2018

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Antiproliferative effect of resveratrol in pancreatic cancer cells

7 July 2018

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Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line

7 July 2018

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Therapy-induced senescence in cancer

7 July 2018

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Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.

7 July 2018

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Cancer prevention with natural compounds

7 July 2018

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Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis.

7 July 2018

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Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin

7 July 2018

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Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells

7 July 2018

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Resveratrol bioavailability and toxicity in humans

7 July 2018

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Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

7 July 2018

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Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer

7 July 2018

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TAp63 induces senescence and suppresses tumorigenesis in vivo

7 July 2018

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Natural products and colon cancer: current status and future prospects

7 July 2018

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Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1.

7 July 2018

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Redox-directed cancer therapeutics: molecular mechanisms and opportunities

7 July 2018

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Cathepsin D and eukaryotic translation elongation factor 1 as promising markers of cellular senescence

7 July 2018

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7 July 2018

Cancer statistics, 2009

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Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD.

7 July 2018

1 reference

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DNA damage, cellular senescence and organismal ageing: causal or correlative?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

7 July 2018

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Therapeutic potential of resveratrol: the in vivo evidence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Total body irradiation selectively induces murine hematopoietic stem cell senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Resveratrol-induced apoptotic death in human U251 glioma cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts

7 July 2018

1 reference

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When cells get stressed: an integrative view of cellular senescence

7 July 2018

1 reference

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The serial cultivation of human diploid cell strains

7 July 2018

1 reference

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

7 July 2018

1 reference

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Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Cisplatin: from DNA damage to cancer chemotherapy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Persistent oxidative stress in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Production of large amounts of hydrogen peroxide by human tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Resveratrol-induced apoptosis and increased radiosensitivity in CD133-positive cells derived from atypical teratoid/rhabdoid tumor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Plant polyphenols mobilize endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for anticancer properties

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II).

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Oncogene-induced senescence as an initial barrier in lymphoma development

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: implications for anticancer properties

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606183

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23533664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0060065

1 reference

release_uveuzpjmgvcjxei2zhodweh7bi

3 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uveuzpjmgvcjxei2zhodweh7bi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3606183

1 reference

3 August 2017

1 reference