Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation (Q34622934)

3 August 2017

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title

Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation (English)

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3 August 2017

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1

G Marius Clore

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PubMed ID

21280116

3 August 2017

language of work or name

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1 February 2011

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3 August 2017

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3 August 2017

20

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3 August 2017

229-246

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3 August 2017

2

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A transient and low-populated protein-folding intermediate at atomic resolution

3 August 2017

1 reference

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Choreographing an enzyme's dance

7 July 2018

1 reference

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Shifting the equilibrium between the encounter state and the specific form of a protein complex by interfacial point mutations

7 July 2018

1 reference

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Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation.

7 July 2018

1 reference

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Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements

7 July 2018

1 reference

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Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands

7 July 2018

1 reference

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Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy

7 July 2018

1 reference

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Observing biological dynamics at atomic resolution using NMR.

7 July 2018

1 reference

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NMR spectroscopy brings invisible protein states into focus

7 July 2018

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TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

7 July 2018

1 reference

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Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes.

7 July 2018

1 reference

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Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy

7 July 2018

1 reference

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Relaxation dispersion NMR spectroscopy as a tool for detailed studies of protein folding

7 July 2018

1 reference

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The courtship of proteins: understanding the encounter complex

7 July 2018

1 reference

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Linking folding and binding

7 July 2018

1 reference

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De novo protein structure generation from incomplete chemical shift assignments.

7 July 2018

1 reference

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Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement

7 July 2018

1 reference

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Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease.

7 July 2018

1 reference

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Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1.

7 July 2018

1 reference

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Replica exchange simulations of transient encounter complexes in protein-protein association.

7 July 2018

1 reference

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Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy

7 July 2018

1 reference

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Conformational relaxation following hydride transfer plays a limiting role in dihydrofolate reductase catalysis

7 July 2018

1 reference

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Consistent blind protein structure generation from NMR chemical shift data

7 July 2018

1 reference

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Characterization of enzyme motions by solution NMR relaxation dispersion.

7 July 2018

1 reference

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Probing invisible, low-populated States of protein molecules by relaxation dispersion NMR spectroscopy: an application to protein folding

7 July 2018

1 reference

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Dynamic personalities of proteins

7 July 2018

1 reference

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Intrinsic motions along an enzymatic reaction trajectory

7 July 2018

1 reference

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Measurement of bond vector orientations in invisible excited states of proteins

7 July 2018

1 reference

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Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR

7 July 2018

1 reference

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Elucidating transient macromolecular interactions using paramagnetic relaxation enhancement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

Protein structure determination from NMR chemical shifts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

Mechanism of coupled folding and binding of an intrinsically disordered protein

7 July 2018

1 reference

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Intramolecular domain-domain association/dissociation and phosphoryl transfer in the mannitol transporter of Escherichia coli are not coupled

7 July 2018

1 reference

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Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR

7 July 2018

1 reference

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Visualization of transient encounter complexes in protein-protein association.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA.

7 July 2018

1 reference

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The dynamic energy landscape of dihydrofolate reductase catalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

Characterization of the dynamics of biomacromolecules using rotating-frame spin relaxation NMR spectroscopy

7 July 2018

1 reference

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Detecting transient intermediates in macromolecular binding by paramagnetic NMR.

7 July 2018

1 reference

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Weak alignment NMR: a hawk-eyed view of biomolecular structure

7 July 2018

1 reference

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Molecular recycling within amyloid fibrils

7 July 2018

1 reference

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Characterization of nonspecific protein-DNA interactions by 1H paramagnetic relaxation enhancement.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR.

7 July 2018

1 reference

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Ensemble approach for NMR structure refinement against (1)H paramagnetic relaxation enhancement data arising from a flexible paramagnetic group attached to a macromolecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

The energetic cost of domain reorientation in maltose-binding protein as studied by NMR and fluorescence spectroscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

EDTA-derivatized deoxythymidine as a tool for rapid determination of protein binding polarity to DNA by intermolecular paramagnetic relaxation enhancement

7 July 2018

1 reference

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Paramagnetic resonance of biological metal centers

7 July 2018

1 reference

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Biomolecular diffusional association

7 July 2018

1 reference

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Paramagnetic probes in metalloproteins

7 July 2018

1 reference

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Nuclear magnetic resonance methods for quantifying microsecond-to-millisecond motions in biological macromolecules

7 July 2018

1 reference

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Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy

7 July 2018

1 reference

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Utilization of site-directed spin labeling and high-resolution heteronuclear nuclear magnetic resonance for global fold determination of large proteins with limited nuclear overhauser effect data

7 July 2018

1 reference

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Protein global fold determination using site-directed spin and isotope labeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048409

Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr

7 July 2018

1 reference

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Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor

7 July 2018

1 reference

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NMR spectroscopic studies of paramagnetic proteins: iron-sulfur proteins.

7 July 2018

1 reference

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Brownian dynamics of cytochrome c and cytochrome c peroxidase association

7 July 2018

1 reference

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Two-dimensional 1H NMR of three spin-labeled derivatives of bovine pancreatic trypsin inhibitor

7 July 2018

1 reference

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Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy

7 July 2018

1 reference

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Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis

7 July 2018

1 reference

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Solution NMR spin relaxation methods for characterizing chemical exchange in high-molecular-weight systems.

7 July 2018

1 reference

Effects of Diffusion on Free Precession in Nuclear Magnetic Resonance Experiments

21 January 2018

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Theoretical study of R(1rho) rotating-frame and R2 free-precession relaxation in the presence of n-site chemical exchange.

21 January 2018

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Accurate measurement of alpha proton chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy

21 January 2018

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Measuring 13Cbeta chemical shifts of invisible excited states in proteins by relaxation dispersion NMR spectroscopy.

21 January 2018

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Enzyme dynamics during catalysis measured by NMR spectroscopy

21 January 2018

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Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair

21 January 2018

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Relaxation Processes in a System of Two Spins

21 January 2018

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Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory.

21 January 2018

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Rational design of faster associating and tighter binding protein complexes.

21 January 2018

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Diffusional encounter of barnase and barstar

21 January 2018

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Visualization of transient ultra-weak protein self-association in solution using paramagnetic relaxation enhancement.

21 January 2018

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Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange.

21 January 2018

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Structural characterization of proteins with an attached ATCUN motif by paramagnetic relaxation enhancement NMR spectroscopy.

21 January 2018

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Direct Observation of Enhanced Translocation of a Homeodomain between DNA Cognate Sites by NMR Exchange Spectroscopy

21 January 2018

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Probing Chemical Shifts of Invisible States of Proteins with Relaxation Dispersion NMR Spectroscopy: How Well Can We Do?

21 January 2018

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Rapid, electrostatically assisted association of proteins

21 January 2018

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12 December 2020

A single-quantum methyl 13C-relaxation dispersion experiment with improved sensitivity

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12 December 2020

Role of electrostatic interactions in transient encounter complexes in protein-protein association investigated by paramagnetic relaxation enhancement

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12 December 2020

Probing structure in invisible protein states with anisotropic NMR chemical shifts

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12 December 2020

Using relaxation dispersion NMR spectroscopy to determine structures of excited, invisible protein states

1 reference

12 December 2020

Binding hot spot in the weak protein complex of physiological redox partners yeast cytochrome C and cytochrome C peroxidase

1 reference

12 December 2020

Visualization of the encounter ensemble of the transient electron transfer complex of cytochrome c and cytochrome c peroxidase

1 reference

12 December 2020

Orienting domains in proteins using dipolar couplings measured by liquid-state NMR: differences in solution and crystal forms of maltodextrin binding protein loaded with beta-cyclodextrin

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12 December 2020

Reweighted atomic densities to represent ensembles of NMR structures

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12 December 2020

Extending the range of amide proton relaxation dispersion experiments in proteins using a constant-time relaxation-compensated CPMG approach

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12 December 2020

Distance measurements in spin-labeled lysozyme

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12 December 2020

Spin labeling of proteins

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12 December 2020

Identifiers

DOI

10.1002/PRO.576

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

21280116