Free-energy cost for translocon-assisted insertion of membrane proteins (Q34621299)

3 August 2017

Free-energy cost for translocon-assisted insertion of membrane proteins (English)

1 reference

3 August 2017

1 reference

3

Klaus Schulten

1 reference

3 August 2017

1

James Gumbart

1 reference

3 August 2017

Christophe Chipot

2

1 reference

PubMed ID

21317362

3 August 2017

language of work or name

English

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publication date

11 February 2011

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

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3 August 2017

108

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3 August 2017

3596-3601

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3 August 2017

9

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On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Hydrophobically stabilized open state for the lateral gate of the Sec translocon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Regulation of the Protein-Conducting Channel by a Bound Ribosome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Protein contents in biological membranes can explain abnormal solvation of charged and polar residues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Insertion of short transmembrane helices by the Sec61 translocon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Translocation of proteins through the Sec61 and SecYEG channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

The lateral gate of SecYEG opens during protein translocation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

The roles of pore ring and plug in the SecY protein-conducting channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Conformational transition of Sec machinery inferred from bacterial SecYE structures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Structure of a complex of the ATPase SecA and the protein-translocation channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

How translocons select transmembrane helices

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Prediction of membrane-protein topology from first principles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

A continuum method for determining membrane protein insertion energies and the problem of charged residues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Distribution of amino acids in a lipid bilayer from computer simulations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Protein translocation across the bacterial cytoplasmic membrane.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Is arginine charged in a membrane?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Position-resolved free energy of solvation for amino acids in lipid membranes from molecular dynamics simulations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Partitioning of amino acid side chains into lipid bilayers: results from computer simulations and comparison to experiment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Membrane protein insertion: the biology-physics nexus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

On the thermodynamic stability of a charged arginine side chain in a transmembrane helix

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Molecular dynamics studies of the archaeal translocon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Scalable molecular dynamics with NAMD

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Recognition of transmembrane helices by the endoplasmic reticulum translocon.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Membrane-protein integration and the role of the translocation channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

X-ray structure of a protein-conducting channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Sec-dependent membrane protein biogenesis: SecYEG, preprotein hydrophobicity and translocation kinetics control the stop-transfer function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

VMD: visual molecular dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

A simple method for displaying the hydropathic character of a protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Molecular code for transmembrane-helix recognition by the Sec61 translocon

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Membrane Insertion of Marginally Hydrophobic Transmembrane Helices Depends on Sequence Context

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

The role of lipid composition for insertion and stabilization of amino acids in membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Titratable Amino Acid Solvation in Lipid Membranes as a Function of Protonation State

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

High‐Temperature Equation of State by a Perturbation Method. I. Nonpolar Gases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Good practices in free-energy calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Mechanism of unassisted ion transport across membrane bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Comparing the polarities of the amino acids: side-chain distribution coefficients between the vapor phase, cyclohexane, 1-octanol, and neutral aqueous solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Competition between neighboring topogenic signals during membrane protein insertion into the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

Structural determinants of lateral gate opening in the protein translocon

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048118

Are Solvation Free Energies of Homogeneous Helical Peptides Additive?

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012758108

The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain

21 January 2018

1 reference

12 December 2020

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

1 reference

12 December 2020

Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes

1 reference

12 December 2020

Competition between neighboring topogenic signals during membrane protein insertion into the ER

1 reference

12 December 2020

Slow translocon gating causes cytosolic exposure of transmembrane and lumenal domains during membrane protein integration

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1012758108

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference

PubMed ID

21317362