The Lkb1 metabolic sensor maintains haematopoietic stem cell survival (Q34568200)

3 August 2017

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival (English)

1 reference

3 August 2017

14

Nabeel Bardeesy

0 references

Borja Saez

Borja Saez

6

0 references

Francesco Ferrari

Francesco Ferrari

10

0 references

Orian S Shirihai

Orian S Shirihai

12

0 references

David T Scadden

13

David T Scadden

1 reference

3 August 2017

Sushma Gurumurthy

1

1 reference

3 August 2017

Stephanie Z Xie

2

1 reference

3 August 2017

Brinda Alagesan

3

1 reference

3 August 2017

Judith Kim

4

1 reference

3 August 2017

Rushdia Z Yusuf

5

1 reference

3 August 2017

Alexandros Tzatsos

7

1 reference

3 August 2017

Fatih Ozsolak

8

1 reference

3 August 2017

Patrice Milos

9

1 reference

3 August 2017

Peter J Park

11

1 reference

3 August 2017

Nabeel Bardeesy

14

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 December 2010

1 reference

3 August 2017

1 reference

3 August 2017

468

1 reference

3 August 2017

659-663

1 reference

3 August 2017

7324

1 reference

https://scigraph.springernature.com/pub.10.1038/nature09572

3 August 2017

0 references

cites work

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

7 July 2018

Direct RNA sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Bmi1 regulates mitochondrial function and the DNA damage response pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

LKB1; linking cell structure and tumor suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Self-eating and self-killing: crosstalk between autophagy and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

The LKB1 tumor suppressor negatively regulates mTOR signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

A ubiquitin-like system mediates protein lipidation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Inducible gene targeting in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09572

IFNalpha activates dormant haematopoietic stem cells in vivo.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037591

Restoration of p53 function leads to tumour regression in vivo

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09572

inferred from DOI database lookup

7 January 2021

based on heuristic

Advances in measuring cellular bioenergetics using extracellular flux

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09572

inferred from DOI database lookup

7 January 2021

based on heuristic

A scaling normalization method for differential expression analysis of RNA-seq data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09572

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE09572

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference