Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability (Q34566018)

3 August 2017

Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability (English)

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3 August 2017

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4

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author name string

Zi Yang

series ordinal

1

1 reference

3 August 2017

Joo Y Hong

series ordinal

2

1 reference

3 August 2017

Irina L Derkatch

series ordinal

3

1 reference

3 August 2017

language of work or name

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24 January 2013

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3 August 2017

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3 August 2017

9

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3 August 2017

1

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3 August 2017

e1003236

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Creative Commons Attribution 4.0 International

3 August 2017

start time

24 January 2013

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April 2022 Public Data File from Crossref

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copyrighted

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ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3554615/fullTextXML

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ImageQuant

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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Chaperone networks in protein disaggregation and prion propagation

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Polyglutamine toxicity is controlled by prion composition and gene dosage in yeast

7 July 2018

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An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component

7 July 2018

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A yeast prion, Mod5, promotes acquired drug resistance and cell survival under environmental stress

7 July 2018

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Influence of prion variant and yeast strain variation on prion-molecular chaperone requirements

7 July 2018

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Insight into molecular basis of curing of [PSI+] prion by overexpression of 104-kDa heat shock protein (Hsp104).

7 July 2018

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Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins

7 July 2018

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A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion

7 July 2018

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Molecular chaperone Hsp104 can promote yeast prion generation

7 July 2018

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Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

7 July 2018

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Newly identified prions in budding yeast, and their possible functions

7 July 2018

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[SWI], the prion formed by the chromatin remodeling factor Swi1, is highly sensitive to alterations in Hsp70 chaperone system activity

7 July 2018

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A size threshold limits prion transmission and establishes phenotypic diversity

7 July 2018

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The effects of amino acid composition on yeast prion formation and prion domain interactions

7 July 2018

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Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation

7 July 2018

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Sequestration of essential proteins causes prion associated toxicity in yeast

7 July 2018

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Reciprocal efficiency of RNQ1 and polyglutamine detoxification in the cytosol and nucleus

7 July 2018

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Influence of Hsp70s and their regulators on yeast prion propagation

7 July 2018

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Hsp104 and prion propagation

7 July 2018

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Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates

7 July 2018

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Increased [PSI+] appearance by fusion of Rnq1 with the prion domain of Sup35 in Saccharomyces cerevisiae.

7 July 2018

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Life cycle of yeast prions: propagation mediated by amyloid fibrils

7 July 2018

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A G-protein gamma subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae

7 July 2018

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In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104

7 July 2018

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Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

7 July 2018

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Specificity of the J-protein Sis1 in the propagation of 3 yeast prions

7 July 2018

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Chaperone-dependent amyloid assembly protects cells from prion toxicity

7 July 2018

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Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition

7 July 2018

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Hsp110 chaperones regulate prion formation and propagation in S. cerevisiae by two discrete activities

7 July 2018

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A regulatory role of the Rnq1 nonprion domain for prion propagation and polyglutamine aggregates

7 July 2018

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Insights into the mechanism of prion propagation

7 July 2018

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The role of Sse1 in the de novo formation and variant determination of the [PSI+] prion

7 July 2018

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J-protein co-chaperone Sis1 required for generation of [RNQ+] seeds necessary for prion propagation

7 July 2018

1 reference

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Cell division is essential for elimination of the yeast [PSI+] prion by guanidine hydrochloride.

7 July 2018

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Stress and prions: lessons from the yeast model

7 July 2018

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Nucleotide exchange factors for Hsp70s are required for [URE3] prion propagation in Saccharomyces cerevisiae

7 July 2018

1 reference

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Endocytosis machinery is involved in aggregation of proteins with expanded polyglutamine domains

7 July 2018

1 reference

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Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Prion generation in vitro: amyloid of Ure2p is infectious

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Mechanism of prion propagation: amyloid growth occurs by monomer addition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Conformational variations in an infectious protein determine prion strain differences

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Global analysis of protein localization in budding yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

The mechanisms of [URE3] prion elimination demonstrate that large aggregates of Ure2p are dead-end products.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Yeast [PSI+] Prion Aggregates Are Formed by Small Sup35 Polymers Fragmented by Hsp104

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Analysis of the Generation and Segregation of Propagons: Entities That Propagate the [PSI+] Prion in Yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Interactions among prions and prion "strains" in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Antagonistic interactions between yeast [PSI(+)] and [URE3] prions and curing of [URE3] by Hsp70 protein chaperone Ssa1p but not by Ssa2p

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Prions affect the appearance of other prions: the story of [PIN(+)].

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Mechanism of prion loss after Hsp104 inactivation in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Studying protein dynamics in living cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

The role of Sis1 in the maintenance of the [RNQ+] prion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

The relationship between visible intracellular aggregates that appear after overexpression of Sup35 and the yeast prion-like elements [PSI(+)] and [PIN(+)].

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

[URE3] prion propagation in Saccharomyces cerevisiae: requirement for chaperone Hsp104 and curing by overexpressed chaperone Ydj1p

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Nucleated conformational conversion and the replication of conformational information by a prion determinant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI(+)] of Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

Evidence for a protein mutator in yeast: role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion

7 July 2018

1 reference

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The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

The [URE3] prion is an aggregated form of Ure2p that can be cured by overexpression of Ure2p fragments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554615

A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion

7 July 2018

1 reference

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Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae

7 July 2018

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Prion-inducing domain 2-114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments

7 July 2018

1 reference

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Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

7 July 2018

1 reference

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Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae.

7 July 2018

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[PSI] and [URE3] as yeast prions

7 July 2018

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Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

7 July 2018

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[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae

7 July 2018

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Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

7 July 2018

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Agents that cause a high frequency of genetic change from [psi+] to [psi-] in Saccharomyces cerevisiae

7 July 2018

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Novel proteinaceous infectious particles cause scrapie

7 July 2018

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The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number.

7 July 2018

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Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

7 July 2018

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Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

21 January 2018

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A new perspective on Hsp104-mediated propagation and curing of the yeast prion [PSI (+) ].

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

21 January 2018

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Ψ, A cytoplasmic suppressor of super-suppressor in yeast

21 January 2018

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Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion.

21 January 2018

1 reference

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[PSI(+)] aggregate enlargement in rnq1 nonprion domain mutants, leading to a loss of prion in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Prion protein remodelling confers an immediate phenotypic switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Single mother-daughter pair analysis to clarify the diffusion properties of yeast prion Sup35 in guanidine-HCl-treated [PSI] cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Yeast prion protein New1 can break Sup35 amyloid fibrils into fragments in an ATP-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003236

Hsp70/Hsp90 co-chaperones are required for efficient Hsp104-mediated elimination of the yeast [PSI(+)] prion but not for prion propagation

21 January 2018

1 reference

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Rnq1: an epigenetic modifier of protein function in yeast

27 October 2018

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12 December 2020

[Psi(+)] prion generation in yeast: characterization of the 'strain' difference

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12 December 2020

Supporting the structural basis of prion strains: induction and identification of [PSI] variants

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12 December 2020

The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide

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12 December 2020

Yeast galactose permease is related to yeast and mammalian glucose transporters

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12 December 2020

Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein

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12 December 2020

Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae

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12 December 2020

The yeast [PSI+] prion: making sense of nonsense

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12 December 2020

Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM

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12 December 2020

10.1371/JOURNAL.PGEN.1003236

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference