The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling (Q34545176)

2 August 2017

The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling (English)

1 reference

2 August 2017

Dennis Christensen

8

0 references

Stefan Wirtz

Stefan Wirtz

9

0 references

Roland Lang

Roland Lang

13

0 references

Carsten J Kirschning

10

Carsten Kirschning

1 reference

2 August 2017

11

Else Marie Agger

1 reference

Clarissa Prazeres da Costa

2 August 2017

12

Clarissa Prazeres da Costa

1 reference

2 August 2017

Christiane Desel

1

1 reference

2 August 2017

Kerstin Werninghaus

2

1 reference

2 August 2017

Manuel Ritter

3

1 reference

2 August 2017

Katrin Jozefowski

4

1 reference

2 August 2017

Jens Wenzel

5

1 reference

2 August 2017

Norman Russkamp

6

1 reference

2 August 2017

Ulrike Schleicher

7

1 reference

2 August 2017

language of work or name

English

0 references

publication date

7 January 2013

1 reference

2 August 2017

1 reference

2 August 2017

8

1 reference

2 August 2017

e53531

1 reference

2 August 2017

1

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

start time

7 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 July 2018

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Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses

7 July 2018

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Non-canonical inflammasome activation targets caspase-11

7 July 2018

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The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

7 July 2018

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First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses

7 July 2018

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7 July 2018

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Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

7 July 2018

1 reference

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Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

7 July 2018

1 reference

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

7 July 2018

1 reference

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Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation

7 July 2018

1 reference

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Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements

7 July 2018

1 reference

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Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

7 July 2018

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

7 July 2018

1 reference

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The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

7 July 2018

1 reference

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

7 July 2018

1 reference

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NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

7 July 2018

1 reference

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Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

7 July 2018

1 reference

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A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

7 July 2018

1 reference

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

7 July 2018

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In vivo activity of released cell wall lipids of Mycobacterium bovis bacillus Calmette-Guérin is due principally to trehalose mycolates

7 July 2018

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

7 July 2018

1 reference

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

7 July 2018

1 reference

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A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538599

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538599

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

7 July 2018

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

7 July 2018

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Cloning of a new cytokine that induces IFN-gamma production by T cells

7 July 2018

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Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses

7 July 2018

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Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells

21 January 2018

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

21 January 2018

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Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production.

21 January 2018

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Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

21 January 2018

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Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

21 January 2018

1 reference

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The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538599

MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308247

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0053531

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference