Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control (Q34545070)

http://europepmc.org/abstract/PMC/5125522

21 December 2017

review article

1 reference

title

Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control (English)

1 reference

http://europepmc.org/abstract/PMC/5125522

21 December 2017

author

Denes Hnisz

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Richard A. Young

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Daniel S Day

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

0 references

publication date

1 November 2016

1 reference

http://europepmc.org/abstract/PMC/5125522

21 December 2017

published in

Cell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

1188-1200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

Editing DNA Methylation in the Mammalian Genome

5 June 2020

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7 July 2018

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Formation of Chromosomal Domains by Loop Extrusion.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Transcriptional Enhancers: Bridging the Genome and Phenome

7 July 2018

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CTCF Binding Polarity Determines Chromatin Looping.

7 July 2018

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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

7 July 2018

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7 July 2018

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Structural and functional diversity of Topologically Associating Domains

7 July 2018

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Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

7 July 2018

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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

7 July 2018

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CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

7 July 2018

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CTCF/cohesin-binding sites are frequently mutated in cancer

7 July 2018

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Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders

7 July 2018

1 reference

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Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions

7 July 2018

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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

7 July 2018

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Comparative Hi-C reveals that CTCF underlies evolution of chromosomal domain architecture

7 July 2018

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CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

7 July 2018

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Chromatin architecture reorganization during stem cell differentiation.

7 July 2018

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Integrative analysis of 111 reference human epigenomes

7 July 2018

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The selection and function of cell type-specific enhancers

7 July 2018

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Genomic discovery of potent chromatin insulators for human gene therapy

7 July 2018

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7 July 2018

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A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

7 July 2018

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7 July 2018

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7 July 2018

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Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

7 July 2018

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Genome-wide map of regulatory interactions in the human genome

7 July 2018

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Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus

7 July 2018

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The 3D genome in transcriptional regulation and pluripotency

7 July 2018

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Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription

7 July 2018

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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

7 July 2018

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CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.

7 July 2018

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Looping back to leap forward: transcription enters a new era

7 July 2018

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CTCF: an architectural protein bridging genome topology and function

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Transcription factors: from enhancer binding to developmental control

7 July 2018

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Spatial partitioning of the regulatory landscape of the X-inactivation centre

7 July 2018

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

7 July 2018

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Enhancers as information integration hubs in development: lessons from genomics.

7 July 2018

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Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization

7 July 2018

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CTCF-mediated functional chromatin interactome in pluripotent cells

7 July 2018

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Mapping and analysis of chromatin state dynamics in nine human cell types

7 July 2018

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Enhancer function: new insights into the regulation of tissue-specific gene expression

7 July 2018

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Functional and mechanistic diversity of distal transcription enhancers

7 July 2018

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Disruption of genomic neighbourhood at the imprinted IGF2-H19 locus in Beckwith-Wiedemann syndrome and Silver-Russell syndrome

7 July 2018

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Mediator and cohesin connect gene expression and chromatin architecture

7 July 2018

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7 July 2018

Chromosome territories

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An oestrogen-receptor-α-bound human chromatin interactome

7 July 2018

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CTCF: master weaver of the genome

7 July 2018

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The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

7 July 2018

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CTCF-dependent enhancer-blocking by alternative chromatin loop formation

7 July 2018

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Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

7 July 2018

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Divergent transcription from active promoters

7 July 2018

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Chromosome alignment and transvection are antagonized by condensin II.

7 July 2018

1 reference

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CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

7 July 2018

1 reference

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CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

7 July 2018

1 reference

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Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription

7 July 2018

1 reference

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Looping and interaction between hypersensitive sites in the active beta-globin locus

7 July 2018

1 reference

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Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs

7 July 2018

1 reference

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

7 July 2018

1 reference

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Different core promoters possess distinct regulatory activities in the Drosophila embryo

7 July 2018

1 reference

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A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

7 July 2018

1 reference

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Transcriptional activation: a complex puzzle with few easy pieces

7 July 2018

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Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

7 July 2018

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Simian virus 40 tandem repeated sequences as an element of the early promoter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

In vivo sequence requirements of the SV40 early promoter region

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

Developmental regulation of beta-globin gene switching.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

A position-effect assay for boundaries of higher order chromosomal domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

DNA position-specific repression of transcription by a Drosophila zinc finger protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125522

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27863240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

FTO Obesity Variant and Adipocyte Browning in Humans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27863240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromatin compaction by a polycomb group protein complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27863240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2016.10.024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863240%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference