TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival (Q34541693)

2 August 2017

TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival (English)

1 reference

Sivaramakrishnan Venkatabalasubramanian

2 August 2017

1 reference

1 reference

S Mohlin

9

0 references

object named as

S Venkatabalasubramanian

5

0 references

author name string

P L Chavali

1

1 reference

2 August 2017

R K R Saini

2

1 reference

2 August 2017

Q Zhai

3

1 reference

2 August 2017

D Vizlin-Hodzic

4

1 reference

2 August 2017

A Hayashi

6

1 reference

2 August 2017

E Johansson

7

1 reference

2 August 2017

Z-j Zeng

8

1 reference

2 August 2017

S Påhlman

10

1 reference

2 August 2017

L Hansford

11

1 reference

2 August 2017

D R Kaplan

12

1 reference

2 August 2017

K Funa

13

1 reference

2 August 2017

language of work or name

1 reference

30 October 2014

1 reference

2 August 2017

Cell Death and Disease

1 reference

2 August 2017

5

1 reference

2 August 2017

e1502

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

start time

1 October 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/cddis.2014.449

0 references

cites work

TLX controls angiogenesis through interaction with the von Hippel-Lindau protein

1 reference

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The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche

7 July 2018

1 reference

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Network modeling of the transcriptional effects of copy number aberrations in glioblastoma

7 July 2018

1 reference

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Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

O2 regulates stem cells through Wnt/β-catenin signalling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation

7 July 2018

1 reference

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Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal

7 July 2018

1 reference

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Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease

7 July 2018

1 reference

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HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

RNAi-mediated downregulation of MMP-2 activates the extrinsic apoptotic pathway in human glioma xenograft cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Involvement of matrix metalloproteinases in the inhibition of cell invasion and migration through the inhibition of NF-[kappa]B by the new synthesized ethyl 2-[N-p-chlorobenzyl-(2'-methyl)]anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOTO1007) in h

7 July 2018

1 reference

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A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus

7 July 2018

1 reference

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Neural stem cells at the crossroads: MMPs may tell the way.

7 July 2018

1 reference

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Neural and cancer stem cells in tumor suppressor mouse models of malignant astrocytoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas

7 July 2018

1 reference

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

7 July 2018

1 reference

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The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

7 July 2018

1 reference

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Paradigms for glycan-binding receptors in cell adhesion.

7 July 2018

1 reference

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HIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Activation of Akt predicts poor outcome in neuroblastoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Notch signalling regulates stem cell numbers in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

The Tlx gene regulates the timing of neurogenesis in the cortex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Development of chromaffin cells depends on MASH1 function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237266

Altered neural cell fates and medulloblastoma in mouse patched mutants

7 July 2018

1 reference

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.449

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.449

Characterization of glycoconjugate antigens in mouse embryonic neural precursor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.449

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.449

Oct-3/4 promotes migration and invasion of glioblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.449

Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25356871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25356871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25356871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.449

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference