Notch signalling regulates stem cell numbers in vitro and in vivo (Q28248390)

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Ronen R Leker

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Frank Soldner

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Daniel J Hoeppner

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Rea Ravin

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Steve W Poser

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Maria A Rueger

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Soo-Kyung Bae

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Raja Kittappa

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Ronald D G McKay

Notch signaling: cell fate control and signal integration in development

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language of work or name

English

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publication date

17 August 2006

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published in

Nature

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volume

442

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page(s)

823-6

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issue

7104

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cites work

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The phosphoinositide 3-kinase pathway

21 April 2017

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Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation

21 April 2017

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Phosphorylation and activation of p70s6k by PDK1

21 April 2017

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

21 April 2017

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EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells

21 April 2017

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Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

21 April 2017

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Doublecortin expression levels in adult brain reflect neurogenesis

21 April 2017

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Stats: transcriptional control and biological impact

21 April 2017

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Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

21 April 2017

1 reference

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7 January 2021

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

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7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

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7 January 2021

Multiple routes to astrocytic differentiation in the CNS.

1 reference

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7 January 2021

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Medulloblastoma growth inhibition by hedgehog pathway blockade

1 reference

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7 January 2021

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210.

1 reference

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7 January 2021

The intracerebral application of the PPARgamma-ligand pioglitazone confers neuroprotection against focal ischaemia in the rat brain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Hypoxia requires notch signaling to maintain the undifferentiated cell state

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04940

7 January 2021

Identifiers

DOI

10.1038/NATURE04940

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2370891

1027499816

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2370891

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference