Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach (Q34522027)

2 August 2017

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach (English)

1 reference

2 August 2017

15

Nir Hacohen

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Igor Kramnik

11

object named as

Igor Kramnik

1 reference

2 August 2017

Alexandra-Chloé Villani

5

object named as

Alexandra-Chloé Villani

1 reference

2 August 2017

9

John G Doench

1 reference

2 August 2017

Mark N Lee

1

1 reference

2 August 2017

Matthew Roy

2

1 reference

2 August 2017

Shao-En Ong

3

1 reference

2 August 2017

Philipp Mertins

4

1 reference

2 August 2017

Weibo Li

6

1 reference

2 August 2017

Farokh Dotiwala

7

1 reference

2 August 2017

Jayita Sen

8

1 reference

2 August 2017

Megan H Orzalli

10

1 reference

2 August 2017

David M Knipe

12

1 reference

2 August 2017

Judy Lieberman

13

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2 August 2017

Steven A Carr

14

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2 August 2017

language of work or name

English

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publication date

23 December 2012

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2 August 2017

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2 August 2017

14

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2 August 2017

179-185

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2 August 2017

2

1 reference

https://scigraph.springernature.com/pub.10.1038/ni.2509

2 August 2017

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cites work

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Viral immune modulators perturb the human molecular network by common and unique strategies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

HSP90 inhibition by 17-DMAG reduces inflammation in J774 macrophages through suppression of Akt and nuclear factor-κB pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

How SAMHD1 changes our view of viral restriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

HIV DNA is heavily uracilated, which protects it from autointegration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

DCs and NK cells: critical effectors in the immune response to HIV-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Nucleic acid recognition by the innate immune system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

IFI16 is an innate immune sensor for intracellular DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

ABC50 promotes translation initiation in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Regulation of the innate immune response by threonine-phosphatase of Eyes absent

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

The SET complex acts as a barrier to autointegration of HIV-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Trex1 prevents cell-intrinsic initiation of autoimmunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Targeting the oncogene and kinome chaperone CDC37.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Death by a thousand cuts: granzyme pathways of programmed cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Molecular understanding and modern application of traditional medicines: triumphs and trials.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

5'-Triphosphate RNA is the ligand for RIG-I

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

A genomic and functional inventory of deubiquitinating enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Ipr1 gene mediates innate immunity to tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838897

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

7 July 2018

1 reference

Inhibition of virus multiplication by foreign nucleic acid

21 January 2018

1 reference

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

21 January 2018

1 reference

Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes

21 January 2018

1 reference

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NI.2509

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference