Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders (Q34520722)

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English	Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders (English)

1 reference

Europe PubMed Central

2 August 2017

author name string

Gregory F Oxenkrug

1

1 reference

Europe PubMed Central

2 August 2017

publication date

2 September 2010

1 reference

Europe PubMed Central

2 August 2017

Journal of Neural Transmission

1 reference

Europe PubMed Central

2 August 2017

118

1 reference

Europe PubMed Central

2 August 2017

1

1 reference

Europe PubMed Central

2 August 2017

75-85

1 reference

Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1007/s00702-010-0475-7

0 references

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Interferon-gamma (+874) T/A genotypes and risk of IFN-alpha-induced depression

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Tryptophan kynurenine metabolism as a common mediator of genetic and environmental impacts in major depressive disorder: the serotonin hypothesis revisited 40 years later.

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Kynurenines, neurodegeneration and Alzheimer's disease

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The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities

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Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study

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The extended life span of Drosophila melanogaster eye-color (white and vermilion) mutants with impaired formation of kynurenine

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Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status

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The role of neopterin in atherogenesis and cardiovascular risk assessment.

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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

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7 July 2018

Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites

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7 July 2018

Neopterin, a prognostic marker in human malignancies

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Vitamin B6 is associated with depressive symptomatology in Massachusetts elders

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Helminths and the IBD hygiene hypothesis

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Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease.

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Menopause and the metabolic syndrome: the Study of Women's Health Across the Nation

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Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

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Interferon-gamma Low producer genotype +874 overrepresented in Bacillus Calmette-Guerin nonresponding children

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7 July 2018

Does minocycline have antidepressant effect?

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7 July 2018

Genetic and hormonal regulation of tryptophan kynurenine metabolism: implications for vascular cognitive impairment, major depressive disorder, and aging.

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7 July 2018

Insulin resistance as the underlying cause for the metabolic syndrome

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7 July 2018

1 reference

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7 July 2018

Role of kynurenines in the central and peripheral nervous systems

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Immune-modulating effects of melatonin, N-acetylserotonin, and N-acetyldopamine

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Antioxidant effects of N-acetylserotonin: possible mechanisms and clinical implications.

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The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase

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7 July 2018

Neurokynurenines (NEKY) as common neurochemical links of stress and anxiety

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7 July 2018

THE INHERITANCE OF HIGH DENSITY LIPOPROTEIN DEFICIENCY (TANGIER DISEASE)

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7 July 2018

Immune activation and degradation of tryptophan in coronary heart disease

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7 July 2018

Effects of antidepressants on the production of cytokines

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7 July 2018

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

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7 July 2018

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

Allele frequencies of +874T-->A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians

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7 July 2018

Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.

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7 July 2018

Combined inhibition of indoleamine 2,3-dioxygenase and nitric oxide synthase modulates neurotoxin release by interferon-gamma-activated macrophages

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7 July 2018

Distinct categories of immunologic changes in frail elderly.

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7 July 2018

Comparative effects of oxygen on indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase of the kynurenine pathway

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7 July 2018

Anticonvulsant activity of melatonin against seizures induced by quinolinate, kainate, glutamate, NMDA, and pentylenetetrazole in mice.

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7 July 2018

Inhibition of hepatic tryptophan-2,3-dioxygenase: superior potency of melatonin over serotonin.

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7 July 2018

Kynurenines and anxiety.

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7 July 2018

Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome

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7 July 2018

Misexpression of the white (w) gene triggers male-male courtship in Drosophila

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7 July 2018

Regulation of nitric-oxide synthase mRNA expression by interferon-gamma and picolinic acid

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7 July 2018

Studies on the urinary excretion of xanthurenic acid in diabetics.

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7 July 2018

Brain serotonergic activity and plasma amino acid levels in genetically obese Zucker rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

l-Kynurenine Its synthesis and possible regulatory function in brain

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7 July 2018

Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect

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7 July 2018

Age-associated elevation of hypothalamic, threshold to feedback control, and its role in development, ageine, and disease.

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7 July 2018

Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 1. Norharman and 4-phenylimidazole binding to the enzyme as inhibitors and heme ligands

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

Determination of 3-hydroxykynurenine in human brain and plasma by high-performance liquid chromatography with electrochemical detection. Increased concentrations in hepatic encephalopathy

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7 July 2018

Age-related changes in kynurenic acid production in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

Generation of superoxide by purified brain nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

Abnormal tryptophan metabolism and experimental diabetes by xanthurenic acid (XA)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

Properties and function of indoleamine 2,3-dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

7 July 2018

N-acetylserotonin, melatonin and their derivatives improve cognition and protect against beta-amyloid-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Tryptophan metabolism in vitamin B6-deficient mice

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Association of interferon-gamma +874A polymorphism with reduced long-term inflammatory response in haemodialysis patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

C-reactive protein and neopterin levels in healthy non-obese adults

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Neuroprotective role of minocycline in co-cultures of human fetal neurons and microglia

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Neopterin as a predictor of total and cardiovascular mortality in individuals undergoing angiography in the Ludwigshafen Risk and Cardiovascular Health study.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Microglial activation in schizophrenia and minocycline treatment.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Antagonism of kynurenic acid to anxiogens in mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

5-lipoxygenase as a possible biological link between depressive symptoms and atherosclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Antidepressant-like actions of minocycline combined with several glutamate antagonists

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Kynurenic acid is present in the rat brain and its content increases during development and aging processes

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the Health 2000 study

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Neopterin concentrations in blood donors differ between AB0 blood group phenotypes

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Ramelteon attenuates age-associated hypertension and weight gain in spontaneously hypertensive rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Nitric oxide synthase inhibition prevents acute quinolinate-induced striatal neurotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Transcribing the cross-talk of cytokine-induced tetrahydrobiopterin synthesis in endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Association of interferon-gamma +874(T/A) single nucleotide polymorphism with the rate of tryptophan catabolism in healthy individuals

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Differential effects of lipopolysaccharide on lipid peroxidation in F344N, SHR rats and BALB/c mice, and protection of melatonin and NAS against its toxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Biochemical profile and survival in nonagenarians.

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https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Negative emotions and 3-year progression of subclinical atherosclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Association between serum neopterin, obesity and daytime sleepiness in patients with obstructive sleep apnea

1 reference

https://api.crossref.org/works/10.1007%2FS00702-010-0475-7

21 January 2018

Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

27 October 2018

Twenty-four–hour plasma tryptophan concentrations and ratios are below normal in obese subjects and are not normalized by substantial weight reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

27 October 2018

Factors influencing serum neopterin concentrations in a population of blood donors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026891

27 October 2018

Postnatal blocking of interferon-gamma function prevented atherosclerotic plaque formation in apolipoprotein E-knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Metabolic Syndrome Is Associated With Circulating Adipokines in Older Adults Across a Wide Range of Adiposity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between insulin resistance, body mass and neopterin concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and functional analysis of tryptophan transport in Malpighian tubules of Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased T-helper interferon-gamma-secreting cells in obese children

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of a wide range of urinary amine metabolites using a simple high-performance liquid chromatographic technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[White adipose tissue, inflammation and atherosclerosis]

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of hypercholesterolemia on some aspects of immune pattern in the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-Associated Alterations in Splenic iNOS Regulation: Influence of Constitutively Expressed IFN-γ and Correction Following Supplementation with PPARα Activators or Vitamin E

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bariatric surgery cannot prevent tryptophan depletion due to chronic immune activation in morbidly obese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of nifedipine, Ca(2+) antagonist, on activity of MAO inhibitors, N-acetylserotonin and melatonin in the mouse tail suspension test

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing serum neopterin and beta 2-microglobulin levels in a healthy diverse population

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postmenopausal changes in production of type 1 and type 2 cytokines and the effects of hormone replacement therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma enhances biosynthesis of pterins in peripheral blood mononuclear cells by induction of GTP-cyclohydrolase I activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00702-010-0475-7

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

ResearchGate publication ID

0 references

Sitelinks

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