RTL therapy for multiple sclerosis: a Phase I clinical study. (Q34520672)

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15 February 2020

title

RTL therapy for multiple sclerosis: a Phase I clinical study (English)

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0 references

2

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1

Halina Offner

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15 February 2020

author name string

Gregory G Burrows

series ordinal

3

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15 February 2020

Adolph J Ferro

series ordinal

4

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15 February 2020

Arthur A Vandenbark

series ordinal

5

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publication date

20 October 2010

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Journal of Neuroimmunology

15 February 2020

published in

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volume

231

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issue

1-2

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page(s)

7-14

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Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis.

15 February 2020

cites work

1 reference

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Inhibition of CXCR2 signaling promotes recovery in models of multiple sclerosis

7 July 2018

1 reference

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Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand

7 July 2018

1 reference

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The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

7 July 2018

1 reference

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Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE.

7 July 2018

1 reference

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Chemokines and glial cells: a complex network in the central nervous system.

7 July 2018

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Expression of the chemokine receptors CXCR1 and CXCR2 in rat oligodendroglial cells

7 July 2018

1 reference

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Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation.

7 July 2018

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Regulation of encephalitogenic T cells with recombinant TCR ligands

7 July 2018

1 reference

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Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis

7 July 2018

1 reference

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A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS.

7 July 2018

1 reference

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Activation pathways implicate anti-HLA-DP and anti-LFA-1 antibodies as lead candidates for intervention in chronic berylliosis

27 October 2018

1 reference

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Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch.

27 October 2018

1 reference

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Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation

27 October 2018

1 reference

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Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.

27 October 2018

1 reference

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Design, engineering, and production of human recombinant t cell receptor ligands derived from human leukocyte antigen DR2

27 October 2018

1 reference

12 December 2020

Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells

1 reference

12 December 2020

Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness

1 reference

12 December 2020

Design, engineering and production of functional single-chain T cell receptor ligands

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12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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12 December 2020

Reparixin, an Inhibitor of CXCR2 Function, Attenuates Inflammatory Responses and Promotes Recovery of Function after Traumatic Lesion to the Spinal Cord

1 reference

12 December 2020

10.1016/J.JNEUROIM.2010.09.013

Identifiers

DOI

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15 February 2020

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15 February 2020

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